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Akademický článek

Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction

Autor: A. E. Firth, B. W. Jagger, H. M. Wise, C. C. Nelson, K. Parsawar, N. M. Wills, S. Napthine, J. K. Taubenberger, P. Digard, J. F. Atkins

Publikováno v: Open Biology, Vol 2, Iss 10 (2012)

Programmed ribosomal frameshifting is used in the expression of many virus genes and some cellular genes. In eukaryotic systems, the most well-characterized mechanism involves –1 tandem tRNA slippage on an X_XXY_YYZ motif. By contrast, the mechanis

Externí odkaz: https://doaj.org/article/1012ec0bdaff4c22823ce4a2101b064a

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Drop-off during ribosome hopping

Autor: A J, Herr, N M, Wills, C C, Nelson, R F, Gesteland, J F, Atkins

Publikováno v: Journal of molecular biology. 311(3)

Ribosomes bypass a 50 nucleotide non-coding segment of mRNA between the two open reading frames of bacteriophage T4 gene 60 in order to synthesize a topoisomerase subunit. While nearly all ribosomes appear to initiate bypassing, only 50 % resume tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7b43c5d883e87600e0756870e274dd2
https://pubmed.ncbi.nlm.nih.gov/11492998

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Reported translational bypass in a trpR'-lacZ' fusion is accounted for by unusual initiation and +1 frameshifting

Autor: N M, Wills, J A, Ingram, R F, Gesteland, J F, Atkins

Publikováno v: Journal of molecular biology. 271(4)

I. Benhar and H. Engelberg-Kulka reported that a 55 nucleotide translational bypass occurs in decoding a fusion of the Escherichia coli tryptophan repressor, trpR, and lacZ genes. The start of the bypass occurred in the trpR gene and coding resumed i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::113e22116dafccfdaed1c132b528617f
https://pubmed.ncbi.nlm.nih.gov/9281421

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