Zobrazeno 1 - 10
of 71
pro vyhledávání: '"N. M. Smol'nikova"'
Publikováno v:
Pharmaceutical Chemistry Journal. 41:399-402
The reproductive toxicity of the complex plant preparation Rumalaya was studied in experiments on white mongrel rats. Rumalaya at doses of 400 and 2000 mg/kg given via the intragastric route with simultaneous application of cream to the skin was foun
Autor:
A V, Sorokina, S V, Alekseeva, E P, Nemova, L P, Kovalenko, N M, Smol'nikova, E V, Shipaeva, O V, Shreder, I A, Miroshkina, S A, Diukova, N O, Daugel'-Dauge, A V, Kulakova, L G, Kolik, A D, Durnev, S B, Seredenin
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(6)
Preclinical safety investigations of newly synthesized dipeptide compound GB-115 (amide N-phenylhexanoyl-glycyl-L-tryptophan), an antagonist of cholecystokinin receptors, were performed. No animals were lost after GB-115 acute oral administration at
Publikováno v:
Bulletin of experimental biology and medicine. 145(4)
A new anxiolytic afobazole (1-100 mg/kg perorally, Russia) dose-dependently abolished the embryotoxic and teratogenic effects of cyclophosphamide and reduced the range of induced malformations in outbred albino rats. Our results suggest that afobazol
Autor:
Tsirenina Ml, Nemova Ep, N. M. Smol'nikova, Ushakov An, A. B. Kampov-Polevoi, S. V. Krapivin, T. A. Gudasheva, Savchenko Nm, S. S. Trofimov, E. I. Mel'nik, R. U. Ostrovskaya
Publikováno v:
Bulletin of Experimental Biology and Medicine. 110:1664-1667
Autor:
S. S. Trofimov, E. V. Kravchenko, T. A. Voronina, Nemova Ep, R. U. Ostrovskaya, N. M. Smol'nikova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 121:396-398
The use of piracetam from the 8th to the 20th day of postnatal development prevents disruption of the elaboration of the conditioned bilateral avoidance reflex in the shuttle box in mature male offspring of rats which had received ethanol intragastra
Autor:
A D, Durnev, N M, Smol'nikova, E P, Nemova, E A, Val'dman, N I, Avdiunina, B M, Piatin, S B, Seredenin
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 66(6)
Himantane introduced via a gastric tube to pregnant rats in a dose of 10, 30, 50, and 100 mg/kg produced a dose-dependent embryotoxic and teratogenic action. An analysis of the experimental results and published data suggests that the embryotoxicity
Autor:
Kutepova Oa, N. A. Bondarenko, E. V. Kravchenko, R. U. Ostrovskaya, Nemova Ep, N. M. Smol'nikova, T. A. Voronina, S. S. Trofimov
Publikováno v:
Bulletin of Experimental Biology and Medicine. 115:45-47
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 59(6)
The effect of lithium hydroxybutyrate on the development of the fetus and offsprings was studied on a model of alcohol intoxication of male rats. Under such conditions lithium hydroxybutyrate relieved completely the negative action of alcohol on the
Autor:
S S, Trofimov, R U, Ostrovskaia, N M, Smol'nikova, E V, Kravchenko, E P, Nemova, T A, Voronina
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 121(4)
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 59(2)
To study the effect of perinatal alcoholization and its withdrawal on cognitive functions of rats, 25% ethanol solution was administered intragastrically: (1) over the whole period of the rat pregnancy in a dose of 5 g/kg/day; (2) from the Ist day of