Study of the Antiviral Activity of Adamantane-Containing Chemical Compounds

Autor: I. I. LYUBIMOV, E. I. ISAEVA, E. N. VETROVA, A. V. LAVROVA, N. M. GRETSKAYA, I. V. SERKOV, V. V. BEZUGLOV, G. A. GALEGOV

Publikováno v: Антибиотики и Химиотерапия, Vol 67, Iss 7-8, Pp 19-23 (2022)

Influenza and coronavirus infections are especially dangerous due to being capable of causing pandemics and clinical complications in the nervous and cardiovascular systems, as well as exacerbation of chronic diseases (diabetes mellitus, heart failur

Externí odkaz: https://doaj.org/article/f4c5a02268b04f86937c6332c7f0f56e

Neuroprotective action of amidic neurolipins in models of neurotoxicity on the culture of human neural-like cells SH-SY5Y

Autor: M. G. Akimov, A. M. Ashba, E. V. Fomina-Ageeva, N. M. Gretskaya, N. F. Myasoedov, V. V. Bezuglov

Publikováno v: Доклады Академии наук. 485:625-628

It was established that in neurodegeneration models in the human neuron-like cell line SH-SY5Y, amide derivatives of arachidonic and docosahexaenoic acids were inactive in experiments with MPP+ and CoCl2 but protected from H2O2. The protective activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8a14ee52c5a83ca16f53a0cd3b95379
https://doi.org/10.31857/s0869-56524855625-628

[STUDYING NEUROPROTECTIVE ACTIVITY OF GABA CONJUGATE WITH ARACHIDONIC ACID UNDER CONDITIONS OF LOCAL PERMANENT BRAIN ISCHEMIA IN RATS]

Autor: N R, Mirzoyan, N G, Hostikyan, A G, Stepanyan, A A, Akopyan, K B, Alikhanyan, V S, Meliksetyan, N A, Bagdasaryan, N M, Gretskaya, V V, Bezuglov

Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia. 78(6)

We have studied the effect of a GABA conjugate with arachidonic acid (AA) on the morphological state of rat brain tissues after left median cerebral artery occlusion. The results showed that a 6- and 12-day course administration of the GABA - AA conj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c7df2fe05dc1d3ba95b1fd7f6b7a30b
https://pubmed.ncbi.nlm.nih.gov/26292507

N-acyl-dopamines: novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo

Autor: T, Bisogno, D, Melck, Bobrov MYu, N M, Gretskaya, V V, Bezuglov, L, De Petrocellis, V, Di Marzo

Publikováno v: Biochemical journal (Lond., 1984) 351 (2000): 817–824. doi:10.1042/0264-6021:3510817
info:cnr-pdr/source/autori:Bisogno T, Melck D, Bobrov MYu, Gretskaya NM, Bezuglov VV, De Petrocellis L, Di Marzo V./titolo:N-acyl-dopamines: novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo/doi:10.1042%2F0264-6021:3510817/rivista:Biochemical journal (Lond., 1984)/anno:2000/pagina_da:817/pagina_a:824/intervallo_pagine:817–824/volume:351

We reported previously that synthetic amides of polyunsaturated fatty acids with bioactive amines can result in substances that interact with proteins of the endogenous cannabinoid system (ECS). Here we synthesized a series of N-acyl-dopamines (NADAs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b267fc7aa9026d2cde3765c42e700c23
https://publications.cnr.it/doc/196918