Zobrazeno 1 - 4
of 4
pro vyhledávání: '"N. Lynn Kelly"'
Publikováno v:
Experimental Cell Research. 312:2347-2357
Dysregulation of apoptosis is involved in a wide spectrum of disease ranging from proliferative to degenerative disorders. An emerging area of study in apoptosis is the critical contribution of the endoplasmic reticulum (ER) in both mitochondrial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb984271c8eaf50f69a2b9e6b237218
https://doi.org/10.1016/j.yexcr.2006.03.027
https://doi.org/10.1016/j.yexcr.2006.03.027
Autor:
N. Lynn Kelly, Robert G. Korneluk, Audrey Brewster, Herman H. Cheung, Martine St. Jean, Shawn T. Beug, Shaomeng Wang
Publikováno v:
The Journal of biological chemistry. 285(52)
Smac mimetic compounds (SMCs) potentiate TNFα-mediated cancer cell death by targeting the inhibitor of apoptosis (IAP) proteins. In addition to TNFα, the tumor microenvironment is exposed to a number of pro-inflammatory cytokines, including IL-1β.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641816b430dd69402a65353e4cdb7a2e
https://pubmed.ncbi.nlm.nih.gov/20956527
https://pubmed.ncbi.nlm.nih.gov/20956527
Autor:
N. Lynn Kelly, Constance Craig, Shingo Toji, Michael W. McBurney, Peter Liston, Damiano Conte, Toshiaki Miyazaki, Katsuyuki Tamai, Robert G. Korneluk, Wai Gin Fong
Publikováno v:
Nature cell biology. 3(2)
The inhibitors of apoptosis (IAPs) suppress apoptosis through the inhibition of the caspase cascade and thus are key proteins in the control of cell death. Here we have isolated the protein XIAP-associated factor 1 (XAF1) on the basis of its ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba2901ec06872ff7a2c41ce501c0431
https://pubmed.ncbi.nlm.nih.gov/11175744
https://pubmed.ncbi.nlm.nih.gov/11175744
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