Zobrazeno 1 - 8
of 8
pro vyhledávání: '"N. L. Nadon"'
Autor:
John H. Morrison, Carol A. Barnes, Kevin M. Kelly, N. L. Nadon, Eric M. Blalock, Olivier Thibault
Publikováno v:
Epilepsy Research. 68:5-20
Basic principles of the neurobiology of aging were reviewed within selected topic areas chosen for their potential relevance to epileptogenesis in the aging brain. The availability of National Institute on Aging-supported aged mouse and rat strains a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debaf24920f9dae3bf713c677b33fe64
https://doi.org/10.1016/j.eplepsyres.2005.07.015
https://doi.org/10.1016/j.eplepsyres.2005.07.015
Autor:
Kay L. Medina, N. L. Nadon, C.-J. Doersen, Michael D. Rohrer, Jeffrey M. Gimble, Linda F. Thompson, D. A. Lade
Publikováno v:
Calcified Tissue International. 67:449-454
The 6093 line of transgenic mice exhibits altered bone development as a result of an insertional mutation by the transgene. Female transgenic mice show a marked kyphosis as early as 2 weeks of age. Vertebrae from female mice have lower total bone are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a46be3d45979ce08d5d44d92814564
https://doi.org/10.1007/s002230001186
https://doi.org/10.1007/s002230001186
Autor:
N L Nadon, S. M. Jamshedur Rahman, M Franklin, Regina Resta, Thomas B. Knudsen, Scott W. Hooker, Linda F. Thompson, Aletha B. Laurent
Publikováno v:
Journal of Clinical Investigation. 99:676-683
The adenosine producing enzyme ecto-5'-nucleotidase (5'-NT) is not normally expressed during thymocyte development until the medullary stage. To determine whether earlier expression would lead to adenosine accumulation and/or be deleterious for thymo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000f10d1af0fcff55f870e5dadaa97d0
https://doi.org/10.1172/jci119211
https://doi.org/10.1172/jci119211
Autor:
N L, Nadon
Publikováno v:
The Journal of comparative neurology. 416(2)
Transgenic mice were produced that carry a construct encoding a mutant form of the DM20 isoform of myelin proteolipid protein. The transgene is under the direction of the human Plp gene promoter, which has previously been shown to direct tissue-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86cd2c4274863cf8f34c20c15be0449a
https://pubmed.ncbi.nlm.nih.gov/10581470
https://pubmed.ncbi.nlm.nih.gov/10581470
Publikováno v:
Journal of neuroscience research. 47(3)
A point mutation in exon 3 of the proteolipid protein (PLP) gene of the myelin-deficient (md) rat leads to a failure of oligodendrocyte maturation and early death of oligodendrocytes, resulting in dysmyelination. It has been suggested that an alterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27866102f8596cf73978038801cf656e
https://pubmed.ncbi.nlm.nih.gov/9039648
https://pubmed.ncbi.nlm.nih.gov/9039648
Publikováno v:
Developmental neuroscience. 19(4)
We previously showed that the jimpy-4J mouse mutation is located on the X chromosome, in or closely linked to the proteolipid protein (Plp) gene. The phenotype is characterized by the most severe hypomyelination of any of the naturally occurring myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7412b50899de749561ab7c388783b8f
https://pubmed.ncbi.nlm.nih.gov/9215879
https://pubmed.ncbi.nlm.nih.gov/9215879
Autor:
Michael R. Wells, Katharine F. Lunn, Charles K. Csiza, N. L. Nadon, R. L. Hoffman, Ian D. Duncan
Publikováno v:
Journal of neurocytology. 24(10)
This study has examined cellular and molecular aspects of glial cell function in a newly described long-lived myelin deficient rat mutant. In contrast to the shorter-lived mutants which died at 25-30 days, the longer-lived mutant rats lived to 75-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa64f48abebfb468b9b56e1eaa9835a
https://pubmed.ncbi.nlm.nih.gov/8586995
https://pubmed.ncbi.nlm.nih.gov/8586995
Autor:
N. L. Nadon, Ian D. Duncan
Publikováno v:
Journal of neuroscience research. 41(1)
The proteolipid proteins play a major role in the structure of the CNS myelin sheath, but they have also been implicated in the oligodendrocyte development leading to myelination. Mutations in the PLP gene result in severe dysmyelination and a paucit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c3f557549c5f65fde330a293dcb7b8
https://pubmed.ncbi.nlm.nih.gov/7674382
https://pubmed.ncbi.nlm.nih.gov/7674382