Zobrazeno 1 - 10
of 12
pro vyhledávání: '"N. L. Koryagina"'
Publikováno v:
Journal of Analytical Chemistry. 77:1664-1668
Publikováno v:
Journal of Analytical Chemistry. 76:1029-1042
The review considers and summarizes separation and preconcentration methods used in the determination of toxicants of the 1st hazard class, namely, organophosphorus nerve agents (a group of Vx isomers, sarin, cyclosarin, soman, and tabun) and blister
Publikováno v:
Analitika i kontrol` (Analytics and control); Том 25, № 2 (2021); P. 110-116
Аналитика и контроль; Том 25, № 2 (2021); P. 110-116
Аналитика и контроль; Том 25, № 2 (2021); P. 110-116
A rapid, unified, highly sensitive and selective procedure for bis(2-chloroethyl)sulfide (sulfur mustard, SM) determination in matrices with high sorption activity using gas chromatography-tandem mass-spectrometry (GC-MS/MS) was developed. Ceramic ti
Autor:
N. L. Koryagina, A. S. Radilov, G. V. Karakashev, T. I. Aliushina, E. I. Savel’eva, N. S. Khlebnikova
Publikováno v:
Journal of Analytical Chemistry. 74:1341-1348
A procedure for the determination of phosphonylated tyrosine, a marker of exposure to organophosphorus nerve agents, in dried blood plasma spot (DBS) samples by means of liquid chromatography/tandem high-resolution mass spectrometry was developed. Th
Autor:
A. S. Radilov, E. I. Savel’eva, N. L. Koryagina, A. I. Ukolov, N. S. Khlebnikova, M. D. Shachneva
Publikováno v:
Journal of Analytical Chemistry. 73:1269-1274
Features of the electron and chemical ionization mass spectra of derivatives of N-[2-[(hydroxyethyl)thio]ethyl]-DL-valine (НЕТЕ-Val)—a biomarker of sulfur mustard—recorded by GC–MS and GC–MS/MS are studied. The retention indices of the st
Publikováno v:
Journal of Analytical Chemistry. 73:1209-1216
A unified procedure is proposed for the determination of thiodiglycol (TDG) and its oxide (TDGO) as markers of exposure to sulfur mustard in biomedical samples (urine, blood plasma, hairs) by gas chromatography–electron ionization mass spectrometry
Autor:
N. S. Khlebnikova, Nikolay V. Goncharov, A. S. Radilov, N. L. Koryagina, D. S. Prokofieva, E. S. Ukolova, E. I. Savelieva, G. V. Karakashev
Publikováno v:
Toxicological Review. :8-16
The effect of the Pelixim antidote on the possibility to detect markers of G type nerve agents sarin and soman was studies in bio probes obtained in an acute in vivo experiment after exposure of rats to organophosphorus nerve agents in doses of 0.5LD
Autor:
A. S. Radilov, A. I. Ukolov, G. V. Karakashev, E. S. Ukolova, N. L. Koryagina, E. I. Savel’eva, N. S. Khlebnikova
Publikováno v:
Journal of Analytical Chemistry. 71:1309-1318
The potentials of different chromatography–mass spectrometry methods for the determination of alkyl methylphosphonic acids (AMPAs)—the chemical markers of nerve agents in urine—are compared. The gas chromatography–mass spectrometry (GC–MS)
Publikováno v:
Pharmaceutical Chemistry Journal. 50:548-552
The need to screen the kinetic characteristics of pharmaceuticals in early development stages is justified. The advantages and limitations of cassette dosing in pharmacokinetic investigations are discussed. The dose and the presence or absence of pha
Autor:
A. S. Radilov, N. S. Khlebnikova, E. I. Savel’eva, G. V. Karakashev, E. A. Murashko, V. N. Babakov, Ya. A. Dubrovskii, A. I. Ukolov, V. Yu. Koneva, V. A. Kopeikin, E. S. Ukolova, N. L. Koryagina
Publikováno v:
Journal of Analytical Chemistry. 71:849-859
A comparative study of the efficiency of procedures for the determination of the biomarkers of organophosphorus agents (OPAs) in blood plasma was performed. It was found that the gas chromatography–mass spectrometry determination of OPAs reactivate