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pro vyhledávání: '"N. Kutinová Canová"'
Publikováno v:
Physiological Research. :S715-S722
Development of a new dug is a very lengthy and highly expensive process since only preclinical, pharmacokinetic, pharmacodynamic and toxicological studies include a multiple of in silico, in vitro, in vivo experimentations that traditionally last sev
Publikováno v:
Physiol Res
Development of a new dug is a very lengthy and highly expensive process since only preclinical, pharmacokinetic, pharmacodynamic and toxicological studies include a multiple of in silico, in vitro, in vivo experimentations that traditionally last sev
Autor:
A, Skotnicová, G, Boubínová, Z, Boštíková, Š, Dušková, M, Šulc, N, Kutinová-Canová, J, Mráz, P, Hodek
Publikováno v:
Physiol Res
Dihydromyricetin (DHM) is a natural flavonoid showing several health promoting effects such as protective activity during severe alcohol intoxication. The mechanism underlying the effects of DHM on alcohol metabolism is virtually unknown. The present
Akademický článek
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Publikováno v:
Physiological research. 66(3)
Sirtuin activating compounds (STACs) attenuate various type of liver insults through mechanisms which are not fully understood. In the present study, we investigated the ameliorative potential of quercetin (natural polyphenol) and SRT1720 (synthetic
Publikováno v:
Scopus-Elsevier
This mini-review highlights our and others’ experience about in vitro and in vivo models that are being used to follow up events of liver injuries under various hepatotoxic agents and potential hepatoprotective drugs. Due to limitations of the outc
Publikováno v:
Cell Biology and Toxicology. 23:337-354
Increased cytosolic calcium ([Ca2+] i ) and nitric oxide (NO) are suggested to be associated with apoptosis that is a main feature of many liver diseases and is characterized by biochemical and morphological features. We sought to investigate the eve
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
The present review is intended to focus on naturally occurring cytoprotective agents such as resveratrol (trans-3,4’,5-trihydroxystilbene) and other related compounds, probably with similar molecular mechanisms of action and high capacity to find a
Autor:
Kameníková L, N Kutinová-Canová, Hassan Farghali, Potmesil P, Zdeněk Zídek, Eva Kmoníčková, Hodis J
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Certain liver metabolic diseases point to the presence of disturbances in glycogen deposition. Epinephrine raises the cAMP level that activates protein kinase A leading to the activation of phosphorylase and glycogen breakdown. In the present report,
Publikováno v:
Zeitschrift für Gastroenterologie. 43