Zobrazeno 1 - 10
of 199
pro vyhledávání: '"N. Kucharczyk"'
Autor:
Vicky N Kucharczyk, Jerry W. Spears, Terry E Engle, Hyungchul Han, K. Sellins, Emmanuel Caldera, S. L. Archibeque, Brittney Weigel, John J. Wagner
Publikováno v:
Journal of Animal Science. 97:1852-1864
Eight crossbred steers (BW 719.0 ± 65.0 kg) with ruminal and duodenal cannulae were used to examine the effect of trace mineral (TM) source on digestibility; ruminal and duodenal solubility of Cu, Zn, and Mn; and in vitro release of Cu, Zn, and Mn f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985beaa3e2db272e2c0653abd0b4fd19
https://doi.org/10.1093/jas/skz072
https://doi.org/10.1093/jas/skz072
Publikováno v:
Epilepsia. 37:15-18
We studied the distribution of felbamate (FBM) in rat brain using a br ain imaging scanner to analyze thaw-mount autoradiographs. After intravenous injection of 14 C FBM in rats, the autoradiograph distribution of isotope labeling patterns in brain w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420a8beb637d7d5e542215f5bed7cfd0
https://doi.org/10.1111/j.1528-1157.1996.tb00505.x
https://doi.org/10.1111/j.1528-1157.1996.tb00505.x
Autor:
S. Krantic, Jean-Paul Vilaine, Jean-Luc Fauchere, Philip Janiak, C. Guyard, N. Kucharczyk, Christophe Thurieau, A Pillon
Publikováno v:
European Journal of Medicinal Chemistry. 30:115-122
Summary We report on the synthesis and pharmacological properties of a new series of somatostatin analogs. Two lower homologs of lysine, 2,3-diaminopropanoic acid and 2,4-diaminobutyric acid, were prepared and used for cyclization via amide formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a88de2853e12c6fc446c22c9c3274de
https://doi.org/10.1016/0223-5234(96)88216-x
https://doi.org/10.1016/0223-5234(96)88216-x
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 614:285-292
An automated, internal standard high-performance liquid chromatographic method for the simultaneous quantitation of felbamate and its three metabolites in adult and neonatal rat brain and heart tissue homogenates was developed and validated. The homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e8ecde77278492bceef6e9e7296df1
https://doi.org/10.1016/0378-4347(93)80320-4
https://doi.org/10.1016/0378-4347(93)80320-4
Publikováno v:
Biopharmaceutics & Drug Disposition. 14:233-244
The plasma concentrations and relative bioavailability of azelastine hydrochloride (AZ) and its desmethyl metabolite (DAZ) after a single and 10 once-a-day oral doses of 2.5 mg kg-1 AZ were determined in adult male and female and pediatric male and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b37375237a9b4a4c44c537b2c69b061
https://doi.org/10.1002/bdd.2510140306
https://doi.org/10.1002/bdd.2510140306
Publikováno v:
Biomedical Chromatography. 7:7-11
Analytical methods have been developed for the simultaneous quantitation of azelastine (AZ) and desmethylazelastine (DAZ) in guinea pig plasma and lung tissue. The methods require a 1.00 mL plasma sample and a minimum 0.100 g lung sample. Both method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ccc4cd9aa86ee77d0603677892ebeb
https://doi.org/10.1002/bmc.1130070103
https://doi.org/10.1002/bmc.1130070103
Autor:
William Diamantis, K K Wong, K. Nolan, N. Kucharczyk, J. Pivonka, C. N. Langevin, N. Chand, V E Adusumalli, R. D. Sofia, J. K. Wichmann
Publikováno v:
Allergy. 48:19-24
The correlation between the antiasthma activity of azelastine and the concentrations of azelastine and its major metabolite, desmethylazelastine, in the blood and lung were investigated in guinea pigs. Blood and lung tissue samples collected at 15 mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3cb77a0fe65239173f48dfe953d8db
https://doi.org/10.1111/j.1398-9995.1993.tb02170.x
https://doi.org/10.1111/j.1398-9995.1993.tb02170.x
Autor:
N. Kucharczyk
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 612:71-76
A model for the lower limit of quantitation for biomedical chromatographic assays is proposed. It is based on the IUPAC definition for the limit of detection and can be estimated from assay calibration data. It has been applied to ten different sets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9836d1db9c053d394b2a9d87cf609a
https://doi.org/10.1016/0378-4347(93)80369-f
https://doi.org/10.1016/0378-4347(93)80369-f
Autor:
J M, Henlin, J A, Boutin, N, Kucharczyk, C, Desmet-Beaufort, A, Loynel, M, Bertrand, A, Genton, G C, Tucker, G, Atassi, J L, Fauchére
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 57(2)
A complete 331,776-member library of tetrapeptides made of 24 amino acid building blocks was synthesized robotically on solid phase and subjected to a deconvolution based on the inhibitory potency of the sublibraries in a HPLC assay of the S-farnesyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b1f2299c2e701ecfd423804f82dd603
https://pubmed.ncbi.nlm.nih.gov/11168892
https://pubmed.ncbi.nlm.nih.gov/11168892
Publikováno v:
Bone. 18(1)
The anabolic effect of parathyroid hormone (PTH) on bone is partly due to a stimulation of osteoblast proliferation. The PTH signal is transduced by the pathways of adenylyl cyclase (AC)/protein kinase (PK) A and phospholipase C/PKC/Ca++. There is st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c280abc1518a693e66bd7b7307be918
https://pubmed.ncbi.nlm.nih.gov/8717538
https://pubmed.ncbi.nlm.nih.gov/8717538