Zobrazeno 1 - 10
of 28
pro vyhledávání: '"N. Kolyasnikova"'
Autor:
A. A. Abdullina, E. V. Vasileva, V. S. Kudrin, V. B Narkevich, T. A. Gudasheva, K. N. Kolyasnikova, G. I. Kovalev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 3-10 (2020)
Effects of chronic cycloprolylglycine (CPG) and its analogues GZK-001 and GZK-002 treatment at the doses 1 and 2 mg/kg on levels of monoamines and their metabolites in BALB/c mice brain were determined by HPLC. Neurochemical data demonstrated that an
Externí odkaz:
https://doaj.org/article/914ecee0968d48a68f6126a699bf813d
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 25-29 (2020)
In the study of strutural and intracellular distribution of cyclo-t-prolylglycine (CPG) in brain rats in experiments on mongrel white male rats, it was found that CPG determined more in the hippocampus and cerebral cortex with predominant localizatio
Externí odkaz:
https://doaj.org/article/dd7b85a4066b425faa5a125fc1c13f9e
Autor:
T. A. Antipova, K. N. Kolyasnikova, Y. S. Volkova, P. I. Antipov, E. A. Kuznetsova, S. V. Nikolaev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 31-36 (2019)
Resume. Previously in the Zakusov Institute of Pharmacology the linear substituted glyproline GZK-111, N-phenylacetyl-glycyl-L-proline ethyl ester, which is capable to convert into the neuropeptide cyclo-prolylglycine (CPG) in biological media and di
Externí odkaz:
https://doaj.org/article/b17cb99daa53436a9ff3ed2882996661
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 26-29 (2017)
We have studied neuroprotective effect of L-cycloprolylglycine (L-CPG) in vitro experiments. It is shown that L-CPG has neuroprotective effect in the conditions an oxidative stress, glutamate and 6-hydroxydopamine toxicity.
Externí odkaz:
https://doaj.org/article/8e9139a0618f4bd583e116700dffbe59
Autor:
E. A. Ivanova, I. G. Kapitsa, N. N. Zolotov, E. A. Valdman, A. V. Nepoklonov, K. N. Kolyasnikova, T. A. Voronina
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 9-12 (2016)
In two animaL modeLs of parkinsonian syndrome - induced by 1-methyL-4-phenyL-1,2,3,6-tetrahydropiridine (MPTP) in C57BL/6 mice and 6-hydroxidopamine (6-OHDA) in rats noveL antiparkinsonian drug hemantane was shown to reduce the increase of brain Leve
Externí odkaz:
https://doaj.org/article/1a792802021e45d2a1e8e9ec8ebd5cd2
Autor:
A. A. Litvin, G. B. Kolyvanov, P. O. Bochkov, R. V. Shevchenko, A. L. Podol’ko, K. N. Kolyasnikova, V. P. Zherdev
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:310-313
Autor:
K. N. Kolyasnikova, P. Yu. Povarnina, E. A. Kuznetsova, A. G. Alyaeva, T. A. Gudasheva, S. B. Seredenin
Publikováno v:
Pharmaceutical Chemistry Journal. 55:1015-1018
Autor:
A. L. Podol'ko, K. N. Kolyasnikova, P. O. Bochkov, R. V. Shevchenko, V. P. Zherdev, A. A. Litvin, G. B. Kolyvanov, O. Yu. Kravtsova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:618-621
Autor:
A. L. Podol'ko, A. A. Litvin, G. B. Kolyvanov, P. O. Bochkov, K. N. Kolyasnikova, V. P. Zherdev, R. V. Shevchenko
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:298-302
Publikováno v:
Pharmaceutical Chemistry Journal. 54:642-646
The optimal synthetic scheme for the potential nootropic drug GZK-111 (N-phenylacetylglycyl-L-proline ethyl ester) was developed. Three synthetic schemes were tested, each of which included the following steps: 1) esterification of L-proline; 2) prep