Zobrazeno 1 - 10
of 541
pro vyhledávání: '"N. Koenig"'
Autor:
Dawn C. Matthews, Jefferson W. Kinney, Aaron Ritter, Randolph D. Andrews, Erin N. Toledano Strom, Ana S. Lukic, Lauren N. Koenig, Carolyn Revta, Howard M. Fillit, Kate Zhong, Babak Tousi, James B. Leverenz, Howard H. Feldman, Jeffrey Cummings
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION The “A/T/N” (amyloid/tau/neurodegeneration) framework provides a biological basis for Alzheimer's disease (AD) diagnosis and can encompass additional changes such as inflammation (“I”). A spectrum of T/N/I imaging and pl
Externí odkaz:
https://doaj.org/article/928ea7d24f9142e28dbc79c4984a4006
Autor:
Tara L. Hogenson, Hao Xie, William J. Phillips, Merih D. Toruner, Jenny J. Li, Isaac P. Horn, Devin J. Kennedy, Luciana L. Almada, David L. Marks, Ryan M. Carr, Murat Toruner, Ashley N. Sigafoos, Amanda N. Koenig-Kappes, Rachel L.O. Olson, Ezequiel J. Tolosa, Cheng Zhang, Hu Li, Jason D. Doles, Jonathan Bleeker, Michael T. Barrett, James H. Boyum, Benjamin R. Kipp, Amit Mahipal, Joleen M. Hubbard, Temperance J. Scheffler Hanson, Gloria M. Petersen, Surendra Dasari, Ann L. Oberg, Mark J. Truty, Rondell P. Graham, Michael J. Levy, Mojun Zhu, Daniel D. Billadeau, Alex A. Adjei, Nelson Dusetti, Juan L. Iovanna, Tanios S. Bekaii-Saab, Wen Wee Ma, Martin E. Fernandez-Zapico
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
BACKGROUND A patient-derived organoid (PDO) platform may serve as a promising tool for translational cancer research. In this study, we evaluated PDO’s ability to predict clinical response to gastrointestinal (GI) cancers.METHODS We generated PDOs
Externí odkaz:
https://doaj.org/article/f973dfbdbe53458f81a1c8da0742e768
Autor:
Holly C. Sucharski, Emma K. Dudley, Jordan Williams, Revati Dewal, Kristin I. Stanford, Peter J. Mohler, Sara N. Koenig
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 423- (2022)
Externí odkaz:
https://doaj.org/article/e81bd78984ae4eef8bd5e30953d4160d
Autor:
Tyler L. Stevens, Heather R. Manring, Michael J. Wallace, Aaron Argall, Trevor Dew, Peter Papaioannou, Steve Antwi-Boasiako, Xianyao Xu, Stuart G. Campbell, Fadi G. Akar, Maegen A. Borzok, Thomas J. Hund, Peter J. Mohler, Sara N. Koenig, Mona El Refaey
Publikováno v:
Cells, Vol 11, Iss 19, p 3049 (2022)
Arrhythmogenic cardiomyopathy (ACM) is an inherited disorder characterized by fibro-fatty infiltration with an increased propensity for ventricular arrhythmias and sudden death. Genetic variants in desmosomal genes are associated with ACM. Incomplete
Externí odkaz:
https://doaj.org/article/63890685f8b04fc6b2be5d434329bc0f
Autor:
Lauren N. Koenig, Lena M. McCue, Elizabeth Grant, Parinaz Massoumzadeh, Catherine M. Roe, Chengjie Xiong, Krista L. Moulder, Liang Wang, Allyson R. Zazulia, Peggy Kelly, Aylin Dincer, Aiad Zaza, Joshua S. Shimony, Tammie L.S. Benzinger, John C. Morris
Publikováno v:
NeuroImage: Clinical, Vol 29, Iss , Pp 102553- (2021)
Introduction: Stroke and Alzheimer disease share risk factors and often co-occur, and both have been reported to have a higher prevalence in African Americans as compared to non-Hispanic whites. However, their interaction has not been established. Th
Externí odkaz:
https://doaj.org/article/af7dfab371d44d4f8e646e1003beca0d
Autor:
Lauren N. Koenig, Gregory S. Day, Amber Salter, Sarah Keefe, Laura M. Marple, Justin Long, Pamela LaMontagne, Parinaz Massoumazada, B. Joy Snider, Manasa Kanthamneni, Cyrus A. Raji, Nupur Ghoshal, Brian A. Gordon, Michelle Miller-Thomas, John C. Morris, Joshua S. Shimony, Tammie L.S. Benzinger
Publikováno v:
NeuroImage: Clinical, Vol 26, Iss , Pp - (2020)
Introduction: Volumetric biomarkers for Alzheimer disease (AD) are attractive due to their wide availability and ease of administration, but have traditionally shown lower diagnostic accuracy than measures of neuropathological contributors to AD. Our
Externí odkaz:
https://doaj.org/article/7eb1e21ee44f424e90fd20f0cc37cf41
Autor:
Mona El Refaey, Sara Coles, Hassan Musa, Tyler L. Stevens, Michael J. Wallace, Nathaniel P. Murphy, Steve Antwi-Boasiako, Lindsay J. Young, Heather R. Manring, Jerry Curran, Michael A. Makara, Kelli Sas, Mei Han, Sara N. Koenig, Michel Skaf, Crystal F. Kline, Paul M. L. Janssen, Federica Accornero, Maegen A. Borzok, Peter J. Mohler
Publikováno v:
Cells, Vol 11, Iss 4, p 665 (2022)
Zonula occludens-1 (ZO-1) is an intracellular scaffolding protein that orchestrates the anchoring of membrane proteins to the cytoskeleton in epithelial and specialized tissue including the heart. There is clear evidence to support the central role o
Externí odkaz:
https://doaj.org/article/d47c3a9ebc0644c4ae6fa10f1b9d22da
Publikováno v:
Antibiotics, Vol 10, Iss 7, p 855 (2021)
The synthesis and biological activity of several novel nitrothiazole, nitrobenzothiazole, and nitrofuran containing antimicrobial agents for the eradication of biofilm-forming Gram-negative and Gram-positive pathogens is described. Nitazoxanide (NTZ)
Externí odkaz:
https://doaj.org/article/0692aa6dc17c485bb7f97a8cf5e8404d
Autor:
Stephanie LaHaye, Uddalak Majumdar, Jun Yasuhara, Sara N. Koenig, Adrianna Matos-Nieves, Rahul Kumar, Vidu Garg
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 6 (2019)
Congenital heart defects affect ∼2% of live births and often involve malformations of the semilunar (aortic and pulmonic) valves. We previously reported a highly penetrant GATA4 p.Gly296Ser mutation in familial, congenital atrial septal defects and
Externí odkaz:
https://doaj.org/article/cbba6851e3e94a3985c35f1b29905da0
Autor:
T. M. Ayodele Adesanya, Melanie Russell, Ki Ho Park, Xinyu Zhou, Matthew A. Sermersheim, Kristyn Gumpper, Sara N. Koenig, Tao Tan, Bryan A. Whitson, Paul M. L. Janssen, Joy Lincoln, Hua Zhu, Jianjie Ma
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 4 (2019)
Background The aortic valve of the heart experiences constant mechanical stress under physiological conditions. Maladaptive valve injury responses contribute to the development of valvular heart disease. Here, we test the hypothesis that MG53 (mitsug
Externí odkaz:
https://doaj.org/article/357819996e0645e08a54cd77afbb8427