A Novel Analytical Method for the Estimation of Solriamfetol in Plasma Samples by Lc-Ms/Ms

Autor: Ratnakumari Perina., N Kannappan, P Premkumar

Publikováno v: International Journal of Life Science and Pharma Research.

Solriamfetol is a selective dopamine and norepinephrine reuptake inhibitor with wake‐promoting effects. The aim of the present study is to develop a rapid, sensitive and reliable method for the estimation of Solriamfetol in plasma samples using LC-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3318a6aed55dfe9c2e433484a54fc57
https://doi.org/10.22376/ijpbs/lpr.2021.11.5.l129-138

Synthesis of some novel 3- (4-ethoxyphenyl) -5- (4-substituted) -4,5-dihydro-1H-pyrazole derivatives as potent antioxidant agents

Autor: Kalaichelvan V K, T. Subburaju, B. Lakshminarayanan, N. Kannappan

Publikováno v: International Journal of Research in Pharmaceutical Sciences. 11:1571-1577

Pyrazolines are the most useful heterocyclic moiety in Pharmaceutical and Chemical fields and as the most potential molecules for the design of new chemical entities. Nitrogen-containing heterocyclic compounds, pyrazolines and their derivatives showe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99aa909ac1d8714a728a5548e07f2752
https://doi.org/10.26452/ijrps.v11i2.2035

Ethoxylated Head of Chalcones as a New Class of Multi‐Targeted MAO Inhibitors

Autor: Giuseppe Felice Mangiatordi, Bijo Mathew, Hoon Kim, Jae Pil Lee, Seung Cheol Baek, Orazio Nicolotti, Thillainayagam Subburaju, B. Lakshminarayanan, N. Kannappan

Publikováno v: ChemistrySelect 4 (2019): 6614–6619. doi:10.1002/slct.201901093
info:cnr-pdr/source/autori:Lakshminarayanan, Balasubramanian; Baek, Seung Cheol; Lee, Jae Pil; Kannappan, Nagappan; Mangiatordi, Giuseppe Felice; Nicolotti, Orazio; Subburaju, Thillainayagam; Kim, Hoon; Mathew, Bijo/titolo:Ethoxylated Head of Chalcones as a New Class of Multi-Targeted MAO Inhibitors/doi:10.1002%2Fslct.201901093/rivista:ChemistrySelect/anno:2019/pagina_da:6614/pagina_a:6619/intervallo_pagine:6614–6619/volume:4

A series of eleven ethoxysubstituted chalcones (E1-E11) were synthesized and investigated for their inhibitory potential towards human recombinant monoamine oxidase A and B (hMAO-A and hMAO-B, respectively) and acetylcholinesterase (AChE). IC50 value

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eebaa95508fd609d480bac1648f61f1
https://doi.org/10.1002/slct.201901093

DEVELOPMENT AND VALIDATION OF RP-UPLC METHOD FOR SIMULTANEOUS ESTIMATION OF CARVEDILOL AND HYDROCHLOROTHIAZIDE IN PHARMACEUTICAL DOSAGE FORM

Autor: N. Kannappan, G Sivakamasundari

Publikováno v: International Research Journal Of Pharmacy. 9:23-26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9e7aef45f0fe33c7231983203b243ad
https://doi.org/10.7897/2230-8407.09221

[6]-Shogaol, a dietary phenolic compound, induces oxidative stress mediated mitochondrial dependant apoptosis through activation of proapoptotic factors in Hep-2 cells

Autor: N. Kannappan, Govindhan Annamalai, Suresh Kathiresan

Publikováno v: Biomedicine & Pharmacotherapy. 82:226-236

Ginger (Zingiber officinale) is a well-known herb used in ethnomedicine. [6]-shogaol, a phenolic nature is a major constituent of ginger. In this study, we investigated the anticancer activity of [6]-shogaol in Laryngeal cancer (Hep-2) cells. We demo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4603cb5e465436baf34f4a265a6254da
https://doi.org/10.1016/j.biopha.2016.04.044