Zobrazeno 1 - 10
of 565
pro vyhledávání: '"N. Kalia"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 539 (2024)
Iontophoresis enables the non-invasive transdermal delivery of moderately-sized proteins and the needle-free cutaneous delivery of antibodies. However, simple descriptors of protein characteristics cannot accurately predict the feasibility of iontoph
Externí odkaz:
https://doaj.org/article/5ec28ca5df9548cb9630fa6ca029346e
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 202 (2024)
The objective of this study was to investigate the cutaneous delivery of cannabidiol (CBD) from aqueous formulations developed for the targeted local treatment of dermatological conditions. CBD was formulated using a proprietary colloidal drug delive
Externí odkaz:
https://doaj.org/article/6fa8ab52351d4ca7add5c97bb0ed1f85
Autor:
Solene Masloh, Anne Chevrel, Maxime Culot, Anaëlle Perrocheau, Yogeshvar N. Kalia, Samuel Frehel, Rémi Gaussin, Fabien Gosselet, Simon Huet, Magali Zeisser Labouebe, Leonardo Scapozza
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 116 (2024)
Biotherapeutics exhibit high efficacy in targeted therapy, but their oral delivery is impeded by the harsh conditions of the gastrointestinal (GI) tract and limited intestinal absorption. This article presents a strategy to overcome the challenges of
Externí odkaz:
https://doaj.org/article/4b4bcb36b0234098a1e1c6b287e87672
Publikováno v:
In International Journal of Pharmaceutics August 2023
Autor:
Si Gou, Alexandre Porcello, Eric Allémann, Denis Salomon, Patrick Micheels, Olivier Jordan, Yogeshvar N. Kalia
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1708 (2023)
Most marketed HA-based dermal fillers use chemical cross-linking to improve mechanical properties and extend their lifetime in vivo; however, stiffer products with higher elasticity require an increased extrusion force for injection in clinical pract
Externí odkaz:
https://doaj.org/article/ec30232833104a73a21b75dc44767ef9
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1278 (2023)
The aim of this study was to investigate whether subtle differences in molecular properties affected polymeric micelle characteristics and their ability to deliver poorly water-soluble drugs into the skin. D-α-tocopherol-polyethylene glycol 1000 was
Externí odkaz:
https://doaj.org/article/38fe936befc0493fb034c74dbe7c5fc7
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1832 (2022)
The intact porcine eye globe model was used to demonstrate that transscleral iontophoresis could deliver a small protein, cytochrome c (Cyt c), to the posterior segment and to investigate post-iontophoretic biodistribution in the different ocular com
Externí odkaz:
https://doaj.org/article/4ac62058b87d432699d193925f23dd86
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 271 (2022)
Lack of accurate diagnosis and the use of formulations designed to address the poor aqueous solubility of antifungal agents, but not optimized for delivery, contribute to unsatisfactory outcomes for topical treatment of cutaneous mycoses. The objecti
Externí odkaz:
https://doaj.org/article/f06823b638634d7da0fcbf7bc4392f0f
Autor:
Aditya R. Darade, Maria Lapteva, Thomas Hoffmann, Markus Mandler, Achim Schneeberger, Yogeshvar N. Kalia
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 151 (2022)
In vitro transcribed messenger ribonucleic acid (mRNA) constitutes an emerging therapeutic class with several clinical applications. This study presents a systematic comparison of different technologies—intradermal injection, microneedle injection,
Externí odkaz:
https://doaj.org/article/cfab142b19084cf8a3e36d8e21030cd0
Publikováno v:
Targeted Drug Delivery. :349-387