Zobrazeno 1 - 10
of 63
pro vyhledávání: '"N. K. Rushmere"'
Autor:
Carmen W. van den Berg, Matheus de F Fernandes Pedrosa, B. Paul Morgan, Danielle Paixão-Cavalcante, N. K. Rushmere, Rute M. Gonçalves-de-Andrade, Denise V. Tambourgi, Matheus Ferracini
Publikováno v:
Molecular Immunology. 41:831-840
Loxoscelism is the clinical condition produced by the venom of spiders belonging to the genus Loxosceles, which can be observed as two well-defined clinical variants: cutaneous loxoscelism and systemic or viscerocutaneous loxoscelism. We have recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c7f92caf80578c85d4673306242a395
https://doi.org/10.1016/j.molimm.2004.03.027
https://doi.org/10.1016/j.molimm.2004.03.027
Autor:
Julia Margaret Wendy Gee, Janice Mary Knowlden, Bryan Paul Morgan, John F.R. Robertson, Robert Ian Nicholson, Maureen Elaine Harper, N. K. Rushmere
Publikováno v:
International Journal of Cancer. 108:930-936
We have examined the relative mRNA expression of the complement (C) regulatory proteins CD59, CD55 and CD46 in RNA isolated from 50 primary breast cancer specimens using a semiquantitative RT-PCR approach. Having normalized the mRNA expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec965d1c4eb60f2b33e7825ea72a447f
https://doi.org/10.1002/ijc.11606
https://doi.org/10.1002/ijc.11606
Autor:
N. K. Rushmere, B. Paul Morgan, Stephen D. Lawn, Julia E. Rey-Nores, Emmanuel LeBouder, Eduardo Schiffrin, Pascual Ferrara, Michael Affolter, George E. Griffin, Mario O. Labéta, Martin Grigorov
Publikováno v:
The Journal of Immunology. 171:6680-6689
Dysregulation of the initial, innate immune response to bacterial infection may lead to septic shock and death. Toll-like receptors (TLRs) play a crucial role in this innate immune response, and yet the regulatory mechanisms controlling microbial-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c360fbebee7d1a088648225a712d50b3
https://doi.org/10.4049/jimmunol.171.12.6680
https://doi.org/10.4049/jimmunol.171.12.6680
Publikováno v:
The American Journal of Pathology. 157:905-918
This study investigated the capacity of neurons and astrocytes to spontaneously activate the complement system and control activation by expressing complement regulators. Human fetal neurons spontaneously activated complement through the classical pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e19eb2923210412fb6b691f034a8746
https://doi.org/10.1016/s0002-9440(10)64604-4
https://doi.org/10.1016/s0002-9440(10)64604-4
Publikováno v:
Immunology. 99:326-332
This report describes the engineering, expression, purification and functional characterization of a soluble recombinant form of murine CD59 (srMoCD59). We report the expression in Chinese hamster ovary (CHO) cells of a modified mouse CD59 cDNA that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf6f02f0381f02cc9a6f63f44d10047a
https://doi.org/10.1046/j.1365-2567.2000.00936.x
https://doi.org/10.1046/j.1365-2567.2000.00936.x
Publikováno v:
Biochemical Journal. 341:821-829
Molecular cloning of mouse decay accelerating factor (DAF; CD55) predicted two forms of the molecule, one transmembrane (TM) and the other glycosylphosphatidylinositol (GPI)-anchored; these are encoded by separate genes termed Daf-GPI and Daf-TM. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65657b98a0c3087b4b9e729f5fa8f9df
https://doi.org/10.1042/bj3410821
https://doi.org/10.1042/bj3410821
Publikováno v:
Biochemical Society Transactions. 26:49-54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf5083d51a1374a7ad6e86f8246f88b
https://doi.org/10.1042/bst0260049
https://doi.org/10.1042/bst0260049
Publikováno v:
Biochemistry. 36:9423-9428
CD59 is a widely distributed membrane-bound glycoprotein that inhibits the formation of the cytolytic membrane attack complex (MAC) of complement on host cells. CD59 from different species varies in its capacity to inhibit heterologous complement, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac948b8fbbff03b179bd651ba5c98e3
https://doi.org/10.1021/bi970832i
https://doi.org/10.1021/bi970832i
Autor:
Catherine M. Abbott, Shelagh Boyle, J. Fantes, Muriel Lee, Andreas Schedl, Jill Kent, Martin B. Powell, Veronica van Heyningen, Wendy A. Bickmore, N. K. Rushmere
Publikováno v:
Genomics. 42:260-267
We describe the localization of the gene encoding reticulocalbin, a Ca 2+ -binding protein of the endoplasmic reticulum, on human chromosome 11p13 midway between the WT1 and the PAX6 genes and show that it is hemizygously deleted in WAGR individuals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825667ff498fd2e650e7697c6c5db8cb
https://doi.org/10.1006/geno.1997.4706
https://doi.org/10.1006/geno.1997.4706
Publikováno v:
Immunology. 90:640-646
This study reports the expression and functional characterization of the rat analogue of the human complement regulatory molecule CD59. We here describe the expression in chinese hamster ovary (CHO) cells of rat CD59 and a modified rat CD59 in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78f9afb5ccbef63655ecf5b45610bda
https://doi.org/10.1046/j.1365-2567.1997.00200.x
https://doi.org/10.1046/j.1365-2567.1997.00200.x