Zobrazeno 1 - 3
of 3
pro vyhledávání: '"N. K. Ossina"'
Autor:
N. K. Ossina, L. T. Volova, P. A. Lebedev, I. A. Shafieva, E. I. Pugachev, S. A. Goncharenko, S. I. Kuznetsov, O. A. Gusyakova, G. N. Svetlova
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 897-904 (2024)
Currently, gouty arthritis is considered as a polygenic multifactorial autoinflammatory disease caused by activation of the NOD (nucleotide-binding domain) -like protein receptor 3 inflammasome NLRP3. The two cytokines IL-1β and IL-18 are considered
Externí odkaz:
https://doaj.org/article/3b0c34c471cf4bb68546721cdedfce49
Autor:
N. K Ossina, E. I Pugachev, I. A Kolyadenko, V. V Pryazhkina, E. G Shakurov, E. V Orlov, L. T Volova
Publikováno v:
Genes & Cells. 16:43-48
To achieve greater clinical relevance of the newly discovered compounds, modern drug discovery requires disease-targeted assays based on human cells. The specific aim of this study was to design and develop a new cell-based assay for screening of com
Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression
Autor:
J D Knight, L D Tomei, M C Kiefer, V C Powers, E M Shekhtman, S R Umansky, N K Ossina, J R Gilbert, Angela Cannas, P A Fitzpatrick
Publikováno v:
The Journal of biological chemistry. 272(26)
Interferon (IFN)-gamma increases the sensitivity of tumor cell lines, many of which are p53 mutants, to tumor necrosis factor-alpha-mediated and anti-Fas antibody-mediated cell death. To better understand the mechanism of IFN-gamma action in modulati