Zobrazeno 1 - 10
of 49
pro vyhledávání: '"N. K. Golovanova"'
Autor:
N. V. Prokazova, E. V. Gracheva, N. K. Golovanova, V. S. Shishkina, N. N. Samovilova, G. F. Piksina
Publikováno v:
Biomeditsinskaya Khimiya. 59:459-468
Using blood monocytes and lymphocytes from atherosclerotic patients and healthy subjects we have investigated activity of GM3 synthase, cellular levels of ganglioside GM3 and its role in monocyte adhesion to cultured human umbilical vein endothelial
Autor:
Reginald S. A. Lord, Yuri V. Bobryshev, Weiping Cao, Eugene E. Efremov, N. N. Samovilova, Nina V. Prokazova, E. V. Gracheva, Masaki Saito, Dinh T. Tran, Alexander Y. Sobolev, Jinhua Lu, Yulia V. Yurchenko, N. K. Golovanova
Publikováno v:
Atherosclerosis. 184:63-71
We have previously demonstrated that amounts of ganglioside GM3 are markedly higher in human atherosclerotic lesions compared to that in non-diseased arterial tissue. Because the fatty acid composition of GM3 in blood plasma low density lipoproteins
Publikováno v:
Biochemistry (Moscow). 67:1230-1234
Sialidase activity has been determined in homogenates of human aortic intima by measuring the amount of GM1 formed during the incubation of ganglioside GD1a with the tissue homogenates. Areas with atherosclerotic lesions as well as adjacent areas wit
Autor:
Nina V. Prokazova, E. V. Gracheva, Yuri V. Bobryshev, Reginald S. A. Lord, N. D. Zvezdina, N. K. Golovanova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1535(2):87-99
Earlier we reported that atherosclerotic plaques contain cells which were specifically and very intensively stained with anti-GM3 antibodies although no GM3 positive cells were detected in the normal non-diseased arterial intima. Because of their lip
Autor:
Eduard Tararak, O. P. Il'inskaya, E. V. Gracheva, N. N. Samovilova, N. K. Golovanova, N. V. Prokazova
Publikováno v:
Biochemistry (Moscow). 66:397-401
Sialyltransferase activity has been determined in Golgi membrane fractions isolated from atherosclerotic and normal intima of human aorta by measuring the transfer of N-acetylneuraminic acid (NeuAc) from CMP-NeuAc to asialofetuin. The asialofetuin-si
GANGLIOSIDE-MEDIATED METABOLIC SYNCHRONIZATION OF PROTEIN SYNTHESIS ACTIVITY IN CULTURED HEPATOCYTES
Autor:
V. Y. Brodsky, N. K. Golovanova, Nina V. Prokazova, Novikova Te, N. D. Zvezdina, Fateeva Vi, Nechaeva Nv, Inna G. Gvasava
Publikováno v:
Cell Biology International. 24:211-222
An ultradian oscillation of protein synthesis was detected by synchronization of metabolic activity in rat hepatocyte cultures. This oscillation occurs in dense cultures in fresh medium, but not in sparse ones. Metabolic synchronization of sparse cul
Autor:
Valentina L Sadovskaya, Nina V. Prokazova, Reginald S. A. Lord, N. D. Zvezdina, Yuri V. Bobryshev, E. V. Gracheva, N. K. Golovanova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1361:287-294
Immunohistochemical examination showed that sections of intimal atherosclerotic plaques contained cells and cell clusters as well as areas of extracellular matrix specifically stained with antibodies against ganglioside GM3. No immunohistochemical st
Publikováno v:
Biochemistry. Biokhimiia. 74(3)
Metabolism, topology, and possible mechanisms for regulation of the ganglioside GM3 content in the cell are reviewed. Under consideration are biological functions of GM3, such as involvement in cell differentiation, proliferation, oncogenesis, and ap
Autor:
Nina V. Prokazova, N. K. Golovanova, E. V. Gracheva, Igor Rybalkin, Svetlana V. Kashirina, Elena R. Andreeva, T. N. Vlasik, Tat’yana Gurskaya, N. N. Samovilova, Alexander Shevelev
Publikováno v:
Molecular and cellular biochemistry. 330(1-2)
In previous studies, we showed that ganglioside levels (GM3 being the main ganglioside) in human aortic intima isolated from atherosclerotic lesions were 5 times greater compared to intima from non-diseased vascular areas. Recently, we found that GM3
Autor:
A. A. Korotaeva, E. V. Gracheva, Elena R. Andreeva, N. K. Golovanova, Nina V. Prokazova, N. N. Samovilova
Publikováno v:
Biochemistry. Biokhimiia. 72(8)
Agonists of cellular receptors, such as receptor tyrosine kinases, G protein-coupled receptors, cytokine receptors, etc., activate phospholipases (C(gamma), C(beta), A(2), D), sphingomyelinase, and phosphatidylinositol-3-kinase. This produces active