Zobrazeno 1 - 6
of 6
pro vyhledávání: '"N. James Skill"'
Publikováno v:
Journal of Medical Ethics. 44:782-786
Academic health centres have historically treated patients with the most complex of diseases, served as training grounds to teach the next generations of physicians and fostered an innovative environment for research and discovery. The physicians who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eee1292cc7bf85ce49c93416e6ea919
https://doi.org/10.1136/medethics-2016-103937
https://doi.org/10.1136/medethics-2016-103937
Autor:
Melissa E Vickers, Robert E. Saint, N. James Skill, Marie Fisher, Timothy S. Johnson, Richard A. Jones, Ian G. C. Coutts, Martin Griffin, Zoe Hau, John L. Haylor, A. Meguid El Nahas
Publikováno v:
Journal of the American Society of Nephrology. 18:3078-3088
Progressive tissue fibrosis is involved in debilitating diseases that affect organs including the lungs, liver, heart, skin, and kidneys. Recent evidence suggests that tissue transglutaminase, an enzyme that crosslinks proteins, may be involved in ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc452d85b254a226c04143bfd3c80357
https://doi.org/10.1681/asn.2006070690
https://doi.org/10.1681/asn.2006070690
Autor:
Ahmed F. El-Koraie, N. James Skill, Melvin Njloma, Timothy S. Johnson, Nahed M. Baddour, Martin Griffin, A. Meguid El Nahas, Ahmed G. Adam
Publikováno v:
Journal of the American Society of Nephrology. 14:2052-2062
Experimental renal scarring indicates that tissue transglutaminase (tTg) may be associated with the accumulation of extracellular matrix (ECM), both indirectly via TGF-beta1 activation and directly by the formation of epsilon(gamma-glutamyl) lysine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196c2369e083ecc0629f396036b921d8
https://doi.org/10.1097/01.asn.0000079614.63463.dd
https://doi.org/10.1097/01.asn.0000079614.63463.dd
Autor:
Martin Griffin, Toru Sanai, Nigel Mould, Marie Fisher, N. James Skill, Mathew F. Jamie, John L. Haylor, A. Meguid El Nahas, Timothy S. Johnson
Publikováno v:
Laboratory Investigation. 81:705-716
Diabetic nephropathy (DN) is characterized by an early, progressive expansion and sclerosis of the glomerular mesangium leading to glomerulosclerosis. This is associated with parallel fibrosis of the renal interstitium. In experimental renal scarring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c092bf7becdba6fa600d3e7fc5c6447
https://doi.org/10.1038/labinvest.3780279
https://doi.org/10.1038/labinvest.3780279
Autor:
Graham L. Thomas, John L. Haylor, Julie A. Douthwaite, A. Meguid El Nahas, N. James Skill, Timothy S. Johnson, Simon Oldroyd, Martin Griffin
Publikováno v:
Europe PubMed Central
Aston Research Explorer
Aston Research Explorer
It was recently demonstrated that renal tissue transglutaminase (tTg) protein and its catalytic product the epsilon(gamma-glutamyl) lysine protein cross-link are significantly increased in the subtotal (5/6) nephrectomy model (SNx) of renal fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d20d212b0dd3cee394ebc654afa95e
https://pubmed.ncbi.nlm.nih.gov/10505691
https://pubmed.ncbi.nlm.nih.gov/10505691
Publikováno v:
Journal of Medical Ethics; Nov2018, Vol. 44 Issue 11, p782-786, 5p