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Autor:
Apirat Chaikuad, A. E. Pedersen, F. A. Sløk, Stefan Knapp, L. K. Petersen, N. J. V. Hansen, A. B. Christensen, P. Blakskjær, M. Kořínek, J. Dietvorst, J. Holmkvist, Sandra Röhm, L. K. Larsen
Publikováno v:
MedChemComm. 7:1332-1339
A highly specific and potent (7 nM cellular IC50) inhibitor of p38α kinase was identified directly from a 12.6 million membered DNA-encoded small molecule library. This was achieved using the high fidelity yoctoReactor technology (yR) for preparing