Zobrazeno 1 - 10
of 12
pro vyhledávání: '"N. J. Philpott"'
Abnormal cytogenetic clones in patients with aplastic anaemia: response to immunosuppressive therapy
Autor:
Judith C. W. Marsh, Jill Hows, N. J. Philpott, Christine J. Harrison, C. G. Geary, Edward C. Gordon-Smith
Publikováno v:
British Journal of Haematology. 104:271-274
We report the response to immunosuppressive therapy with antithymocyte globulin (ATG) and cyclosporin or oxymetholone in 13 cases of aplastic anaemia (AA) with an abnormal cytogenetic clone detected at or sometime after diagnosis. Blood and bone marr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d042e9e7ed5ac524a33f3e0c3c4307
https://doi.org/10.1046/j.1365-2141.1999.01187.x
https://doi.org/10.1046/j.1365-2141.1999.01187.x
Publikováno v:
British Journal of Haematology. 96:240-247
Fanconi's anaemia (FA) is characterized by increased spontaneous and induced chromosome fragility. This has been widely regarded to be due to a defect in DNA crosslink repair, because of the sensitivity of cells to known DNA crosslinking agents such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ae9a4cfb8dc024b7670805afb0a74a
https://doi.org/10.1046/j.1365-2141.1997.d01-2023.x
https://doi.org/10.1046/j.1365-2141.1997.d01-2023.x
Autor:
Edward C. Gordon-Smith, M. Westby, A. J. C. Turner, Frances M. Gibson, Angus G. Dalgleish, N. J. Philpott, Judith C. W. Marsh, John Scopes
Publikováno v:
Blood. 87:2244-2251
The detection and quantitation of apoptotic cells is becoming increasingly important in the investigation of the role of apoptosis in cellular proliferation and differentiation. The pathogenesis of hematologic disorders such as aplastic anemia and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2907e371721e4340daca57aba8d7921
https://doi.org/10.1182/blood.v87.6.2244.bloodjournal8762244
https://doi.org/10.1182/blood.v87.6.2244.bloodjournal8762244
Abnormal cytogenetic clones in patients with aplastic anaemia: response to immunosuppressive therapy
Publikováno v:
British journal of haematology. 104(2)
We report the response to immunosuppressive therapy with antithymocyte globulin (ATG) and cyclosporin or oxymetholone in 13 cases of aplastic anaemia (AA) with an abnormal cytogenetic clone detected at or sometime after diagnosis. Blood and bone marr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6d97487392855eb8338c235049b06b5
https://pubmed.ncbi.nlm.nih.gov/10050707
https://pubmed.ncbi.nlm.nih.gov/10050707
Publikováno v:
British journal of haematology. 97(1)
The mechanism of release of CD34+ cells into the peripheral blood (PB) after mobilization treatment with chemotherapy and/or growth factors is not clearly understood. Growth factors may induce increased proliferation and self renewal within the stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453e54aa44106dd07c40bd560cde8105
https://pubmed.ncbi.nlm.nih.gov/9136957
https://pubmed.ncbi.nlm.nih.gov/9136957
Autor:
Toon Min, G. J. Swansbury, Jennifer Treleaven, Daniel Catovsky, Melissa Dainton, N. J. Philpott, M. O. Elebute, R. L. Powles, Martin Gore
Publikováno v:
British journal of haematology. 93(4)
With the increasing use of chemotherapy for many different primary malignancies, secondary or therapy-related acute myeloid leukaemias (AML) and myelodysplastic syndromes (MDS) are becoming more common. The risk of developing sAML has been estimated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a7953281a16700a2e475d84048279c
https://pubmed.ncbi.nlm.nih.gov/8703821
https://pubmed.ncbi.nlm.nih.gov/8703821
Autor:
N J, Philpott, A J, Turner, J, Scopes, M, Westby, J C, Marsh, E C, Gordon-Smith, A G, Dalgleish, F M, Gibson
Publikováno v:
Blood. 87(6)
The detection and quantitation of apoptotic cells is becoming increasingly important in the investigation of the role of apoptosis in cellular proliferation and differentiation. The pathogenesis of hematologic disorders such as aplastic anemia and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd581fc7782a273655fb7726595b8831
https://pubmed.ncbi.nlm.nih.gov/8630384
https://pubmed.ncbi.nlm.nih.gov/8630384
Publikováno v:
Experimental hematology. 23(14)
We have quantitated apoptotic cells by flow cytometry in human bone marrow (BM) and peripheral blood (PB) from normal donors and aplastic anemia (AA) patients, using the fluorescent DNA-binding dye 7-amino actinomycin D (7AAD). No significant differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e938e23f20a0eeb3d4f80eb850fbe1d5
https://pubmed.ncbi.nlm.nih.gov/8542959
https://pubmed.ncbi.nlm.nih.gov/8542959
Autor:
N J, Philpott, J C, Marsh, T O, Kumaran, A, Yardumian, M, Lawler, S R, McCann, E C, Gordon-Smith
Publikováno v:
Bone marrow transplantation. 14(1)
We present a patient who was diagnosed as suffering from Fanconi anaemia at the age of 36 years. At the time of diagnosis his bone marrow showed features of pre-leukaemic transformation. He received an allogeneic bone marrow transplant (BMT) from his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::803067d3f81a8a0fab943f801af5b4e0
https://pubmed.ncbi.nlm.nih.gov/7951104
https://pubmed.ncbi.nlm.nih.gov/7951104