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Publikováno v:
Antimicrob Agents Chemother
Candida auris has been shown to have a high risk of skin colonization in hospitalized patients, possibly contributing to nosocomial spread. In a guinea pig skin model, animals were evaluated for clinical appearance, tissue fungal burden, histology, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d34164f4581caecc502d5a38238ec8
https://doi.org/10.1128/aac.00854-20
https://doi.org/10.1128/aac.00854-20
Autor:
Mahmoud A. Ghannoum, David Angulo, Christopher L. Hager, Katyna Borroto-Esoda, Stephen Barat, R. Wilson, Lisa Long, N. Isham
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Ibrexafungerp (formerly SCY-078), a novel glucan synthase inhibitor with oral availability, was evaluated for activity against Candida glabrata . The susceptibility of clinical strains to ibrexafungerp was determined by microdilution and time-kill as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fc1cc079d6bf6d20f2933eda456fa6
https://doi.org/10.1128/aac.01510-19
https://doi.org/10.1128/aac.01510-19
Publikováno v:
Antimicrob Agents Chemother
Ibrexafungerp (formerly SCY-078), a novel glucan synthase inhibitor with oral availability, was evaluated for activity against Candida glabrata. The susceptibility of clinical strains to ibrexafungerp was determined by microdilution and time-kill ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e724013d5d5312ea34b983909d2ce344
https://pubmed.ncbi.nlm.nih.gov/31570395
https://pubmed.ncbi.nlm.nih.gov/31570395
Autor:
N. Isham, Steve Wring, David Angulo, Katyna Borroto-Esoda, Lisa Long, Stephen Barat, Emily L Larkin, Mahmoud A. Ghannoum
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Ibrexafungerp (IBX) (formerly SCY-078) is a novel glucan synthase inhibitor whose oral availability is being evaluated for efficacy against vulvovaginal candidiasis (VVC). Bioavailability and in vitro activity are important efficacy indicators, but a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2681493c90d5ce4c1a79b96b4377cdd3
https://doi.org/10.1128/aac.02611-18
https://doi.org/10.1128/aac.02611-18
Autor:
Masaru Miyagi, Mahmoud A. Ghannoum, Christopher Hager, N. Isham, Jyotsna Chandra, Kory P Schrom, Thomas S. McCormick
Publikováno v:
mBio
mBio, Vol 10, Iss 2, p e00338-19 (2019)
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e00338-19 (2019)
mBio, Vol 10, Iss 2 (2019)
The effects of diversity of the gut microbiome on inflammation have centered mainly on bacterial flora. Recent research has implicated fungal species and their interactions with other organisms in the inflammatory process. New ways to restore microbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5f9ebda59db8be8a06e297bdf04c10
https://doi.org/10.1128/mbio.00338-19
https://doi.org/10.1128/mbio.00338-19
Autor:
Krzysztof Appelt, Pranab K. Mukherjee, Gino J DiSciullo, Jyotsna Chandra, Mahmoud A. Ghannoum, N. Isham, Lisa Long
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
Central-line-associated bloodstream infections are increasingly recognized to be associated with intraluminal microbial biofilms, and effective measures for the prevention and treatment of bloodstream infections remain lacking. This report evaluates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b937654b910c75f41845bca9d6fafc
https://doi.org/10.1128/aac.00722-18
https://doi.org/10.1128/aac.00722-18
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology
Frontiers in Microbiology
The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c975fd8296717ce0770acc99829ba3a
https://www.frontiersin.org/article/10.3389/fmicb.2018.01459/full
https://www.frontiersin.org/article/10.3389/fmicb.2018.01459/full
Autor:
N. Isham, Jyotsna Chandra, Gino J DiSciullo, Pranab K. Mukherjee, Mahmoud A. Ghannoum, Lisa Long, Krzysztof Appelt
Central line associated bloodstream infections (CLABSIs) are increasingly recognized to be associated with intralumenal microbial biofilms, and effective measures for the prevention and treatment of BSI remain lacking. This report evaluates a new com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd59cf63a2edef6c54bbf9e400e5bea6
Autor:
David Angulo, Lisa Long, N. Isham, Stephen Barat, Katyna Borroto-Esoda, Mahmoud A. Ghannoum, R. Sherif, Emily L Larkin
Publikováno v:
Antimicrobial Agents and Chemotherapy
Invasive aspergillosis remains a major cause of death among the immunocompromised population and those receiving long-term immunosuppressive therapy. In light of increased azole resistance, variable outcomes with existing echinocandin monotherapy and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6f5e98a957ce2e91dd28ec985413f4
https://pubmed.ncbi.nlm.nih.gov/29610204
https://pubmed.ncbi.nlm.nih.gov/29610204