Zobrazeno 1 - 6
of 6
pro vyhledávání: '"N. I. Mekhtieva"'
Autor:
N. I. Mekhtieva
Publikováno v:
Опухоли женской репродуктивной системы, Vol 14, Iss 4, Pp 24-34 (2019)
The article considers the modern methods of diagnosis and treatment of primary operable breast cancer depending on molecular biological profile of the tumor.
Externí odkaz:
https://doaj.org/article/930fdc9e4bc44af1af15f56008a4ea75
Autor:
L. N. Lyubchenko, M. G. Filippova, N. I. Mekhtieva, T. A. Shendrikova, A. V. Semaynikhina, A. V. Snegovoy
Publikováno v:
Сибирский онкологический журнал, Vol 16, Iss 6, Pp 73-85 (2017)
Tamoxifen is a drug of choice for endocrine therapy of hormone receptor- positive breast cancer in women of reproductive age. The metabolic activity of tamoxifen is determined by the activity of the CYP2D6 enzyme encoded by the CYP2D6 gene: under the
Externí odkaz:
https://doaj.org/article/64baadb816a64651805d477569a71e27
Autor:
L. N. Lyubchenko, M. G. Filippova, T. A. Shendrikova, L. G. Zhukova, N. I. Mekhtieva, O. V. Krokhina, S. M. Portnoy
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 3, Pp 57-66 (2017)
Tamoxifen is the drug of choice for endocrine therapy of hormone receptor- positive breast cancer in women in the reproductive period. The metabolic activity of tamoxifen is determined by the activity of the enzyme CYP2D6, encoded by the gene of the
Externí odkaz:
https://doaj.org/article/5df6a982317c425dbed172d493dee4f0
Publikováno v:
Bone and soft tissue sarcomas, tumors of the skin. 13:39-47
Background. Standard treatment for hormone receptor-positive breast cancer includes long-term hormone therapy. However, treatment efficacy varies even in homogeneous groups of patients. Tamoxifen is metabolized in the liver, resulting in the producti
Publikováno v:
Voprosy onkologii. 51(3)
Publikováno v:
Voprosy onkologii. 51(3)
The reports deals with the data on repeat large-scale dissection of soft-tissue sarcoma following non-radical removal in 23 patients (13 males and 10 females , aged 14-75; mean age 42+/-30.2 yrs). Repeat surgery was carried out 3-6 weeks after primar