Výsledky vyhledávání - "N. I. Krutetskaya"

Pyrazole Derivative Attenuates Store-Dependent Ca2+ Entry in Rat Peritoneal Macrophages

Autor: Z. I. Krutetskaya, L. S. Milenina, N. I. Krutetskaya, V. G. Antonov

Publikováno v: Cell and Tissue Biology. 15:293-300

Store-dependent Ca2+ entry is a ubiquitous mechanism of regulated Ca2+ entry into eukaryotic cells. It is activated upon depletion of intracellular Ca2+ stores and is involved in the regulation of a wide range of cellular processes. To elucidate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50e77b61a8a6cc450e6ae796b9f99dd6
https://doi.org/10.1134/s1990519x21030068

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The Sigma-1 Receptor Ligand Chlorpromazine Attenuates Store-Dependent Ca2+ Entry in Peritoneal Macrophages

Autor: Z. I. Krutetskaya, V. G. Antonov, N. I. Krutetskaya, L. S. Milenina

Publikováno v: Biophysics. 66:77-83

Using Fura-2AM, a fluorescent Ca2+ indicator, we have shown for the first time that sigma-1 receptor antagonist - neuroleptic chlorpromazine - significantly inhibits the store-dependent Ca2+ entry induced by immunomodulators glutoxim as well as molix

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8d0e292ab96bb756eb05977e9680580
https://doi.org/10.1134/s0006350921010115

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The Sigma-1 Receptor Ligands Chlorpromazine and Trifluoperazine Inhibit Na+ Transport in Frog Skin Epithelium

Autor: A. V. Melnitskaya, V. G. Antonov, Z. I. Krutetskaya, N. I. Krutetskaya

Publikováno v: Biophysics. 65:784-787

Using the voltage-clamp technique, it has been shown for the first time that the neuroleptic drugs chlorpromazine and trifluoperazine, which act as sigma-1 receptor antagonists, attenuate Na+ transport in the frog skin epithelium. The results suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::835ce0fd01c537a8fcfe2ca95c61d8e8
https://doi.org/10.1134/s0006350920050115

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Sigma-1 Receptor Ligands Chlorpromazine and Trifluoperazine Attenuate Ca

Autor: L S, Milenina, Z I, Krutetskaya, V G, Antonov, N I, Krutetskaya

Publikováno v: Cell and tissue biology. 16(3)

Sigma-1 receptors are ubiquitous multifunctional ligand-regulated molecular chaperones in the endoplasmic reticulum membrane with a unique history, structure, and pharmacological profile. Sigma-1 receptors bind ligands of different chemical structure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed00cb5580fbfd760d253d051746725a
https://pubmed.ncbi.nlm.nih.gov/35668825

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