Zobrazeno 1 - 10
of 134
pro vyhledávání: '"N. Harty"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Filovirus-host interactions play important roles in all stages of the virus lifecycle. Here, we identify LATS1/2 kinases and YAP, key components of the Hippo pathway, as critical regulators of EBOV transcription and egress. Specifically, we
Externí odkaz:
https://doaj.org/article/23875c06d84b41d29612e95e37cfb856
Autor:
Ariel Shepley-McTaggart, Jingjing Liang, Yang Ding, Marija A Djurkovic, Valeriia Kriachun, Olena Shtanko, Oriol Sunyer, Ronald N Harty
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011595 (2023)
Ebola (EBOV) and Marburg viruses (MARV) cause severe hemorrhagic fever associated with high mortality rates in humans. A better understanding of filovirus-host interactions that regulate the EBOV and MARV lifecycles can provide biological and mechani
Externí odkaz:
https://doaj.org/article/fbe473186be64d29a4b95c1fd33611c7
Autor:
Elizabeth Rybakovsky, Katherine M. DiGuilio, Mary Carmen Valenzano, Sophie Geagan, Kaithlyn Pham, Ronald N. Harty, James M. Mullin
Publikováno v:
Physiological Reports, Vol 11, Iss 7, Pp n/a-n/a (2023)
Abstract Using the 16HBE 14o‐ human airway epithelial cell culture model, calcitriol (Vitamin D) was shown to improve barrier function by two independent metrics – increased transepithelial electrical resistance (TER) and reduced transepithelial
Externí odkaz:
https://doaj.org/article/97551726850c4e4787451875ffb06e47
Autor:
Ariel Shepley-McTaggart, Cari A Sagum, Isabela Oliva, Elizabeth Rybakovsky, Katie DiGuilio, Jingjing Liang, Mark T Bedford, Joel Cassel, Marius Sudol, James M Mullin, Ronald N Harty
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0251955 (2021)
Newly emerged SARS-CoV-2 is the cause of an ongoing global pandemic leading to severe respiratory disease in humans. SARS-CoV-2 targets epithelial cells in the respiratory tract and lungs, which can lead to amplified chloride secretion and increased
Externí odkaz:
https://doaj.org/article/2040963e947d4968bd423ee2b28d9917
Autor:
Ziying Han, Shantoshini Dash, Cari A Sagum, Gordon Ruthel, Chaitanya K Jaladanki, Corbett T Berry, Michael P Schwoerer, Nina M Harty, Bruce D Freedman, Mark T Bedford, Hao Fan, Sachdev S Sidhu, Marius Sudol, Olena Shtanko, Ronald N Harty
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008231 (2020)
Ebola (EBOV) and Marburg (MARV) are members of the Filoviridae family, which continue to emerge and cause sporadic outbreaks of hemorrhagic fever with high mortality rates. Filoviruses utilize their VP40 matrix protein to drive virion assembly and bu
Externí odkaz:
https://doaj.org/article/2b5a06ea5c4348918068392abc239b3c
Autor:
Elizabeth Rybakovsky, Katherine M. DiGuilio, Mary Carmen Valenzano, Sophie Geagan, Kaithlyn Pham, Ronald N. Harty, James M. Mullin
Publikováno v:
Physiological Reports. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d131f94d49fc257e8de4185e84eb629
https://doi.org/10.14814/phy2.15592
https://doi.org/10.14814/phy2.15592
Autor:
Francisco Castillo, Carles Corbi-Verge, Javier Murciano-Calles, Adela M. Candel, Ziying Han, Manuel Iglesias-Bexiga, Javier Ruiz-Sanz, Philip M. Kim, Ronald N. Harty, Jose C. Martinez, Irene Luque
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
instname
instname
This research has been financed by grants BIO2016-78746-C2-1-R and PID2020-112895RB-100 from the Spanish Ministry of Education and Science (I.L.) including AEI/FEDER EU funds. R.N.H. was funded in part by National Institutes of Health grants AI138052
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1877c791c8c0c7dec7de3cd2d1417ad5
https://doi.org/10.1016/j.ijbiomac.2022.03.010
https://doi.org/10.1016/j.ijbiomac.2022.03.010
Autor:
Ariel Shepley-McTaggart, Michael Patrick Schwoerer, Cari A. Sagum, Mark T. Bedford, Chaitanya K. Jaladanki, Hao Fan, Joel Cassel, Ronald N. Harty
Publikováno v:
Viruses, Vol 13, Iss 2, p 288 (2021)
Filoviruses Ebola (EBOV) and Marburg (MARV) are devastating high-priority pathogens capable of causing explosive outbreaks with high human mortality rates. The matrix proteins of EBOV and MARV, as well as eVP40 and mVP40, respectively, are the key vi
Externí odkaz:
https://doaj.org/article/c5e17d7de27d46759d5f3ea2744a9919
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(2)
The filovirus VP40 protein directs virion egress, which is regulated either positively or negatively by select VP40–host interactions. We demonstrate that host BAG3 and HSP70 recognize VP40 as a client and inhibit the egress of VP40 virus-like part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cf8e49bbcc8f0a05610a3e361bf243
https://pubmed.ncbi.nlm.nih.gov/36598950
https://pubmed.ncbi.nlm.nih.gov/36598950
Autor:
J.A. Aguilar, A. Anker, P. Allison, S. Archambault, P. Baldi, S.W. Barwick, J.J. Beatty, J. Beise, D. Besson, A. Bishop, E. Bondarev, O. Botner, S. Bouma, S. Buitink, M. Cataldo, C.C. Chen, C.H. Chen, P. Chen, Y.C. Chen, T. Choi, B.A. Clark, W. Clay, Z. Curtis-Ginsberg, A. Connolly, L. Cremonesi, P. Dasgupta, J. Davies, S. de Kockere, K.D. de Vries, C. Deaconu, M.A. DuVernois, J. Flaherty, E. Friedman, R. Gaior, G. Gaswint, C. Glaser, A. Hallgren, S. Hallmann, Y.-B. Ham, J.C. Hanson, N. Harty, B. Hendricks, K.D. Hoffman, E. Hong, C. Hornhuber, S.Y. Hsu, L. Hu, J.J. Huang, M.-H. Huang, K. Hughes, A. Ishihara, G. Jee, J. Jung, A. Karle, J.L. Kelley, S.R. Klein, S.A. Kleinfelder, J. Kim, K.-C. Kim, M.-C. Kim, I. Kravchenko, R. Krebs, Y. Ku, C.Y. Kuo, K. Kurusu, Hyuck-Jin Kwon, R. Lahmann, H. Landsman, U. Latif, C. Lee, C.-H. Leung, C.-J. Li, J. Liu, T.-C. Liu, M.-Y. Lu, K. Madison, J. Mammo, K. Mase, S. McAleer, T. Meures, Z.S. Meyers, K. Michaels, M. Mikhailova, K. Mulrey, J. Nam, R.J. Nichol, G. Nir, A. Nelles, A. Novikov, A. Nozdrina, E. Oberla, B. Oeyen, J. Osborn, Y. Pan, H. Pandya, M.P. Paul, C. Persichilli, C. Pfendner, I. Plaisier, N. Punsuebsay, L. Pyras, R. Rice-Smith, J. Roth, D. Ryckbosch, O. Scholten, D. Seckel, M.F.H. Seikh, Y.-S. Shiao, B.-K. Shin, A. Shultz, D. Smith, D. Southall, J. Tatar, J. Torres, S. Toscano, D. Tosi, J. Touart, D.J. Van Den Broeck, N. van Eijndhoven, G.S. Varner, A.G. Vieregg, M.-Z. Wang, S.-H. Wang, Y.H. Wang, C. Welling, D.R. Williams, S. Wissel, C. Xie, S. Yoshida, R. Young, L. Zhao, A. Zink
Publikováno v:
Astroparticle Physics, 145, 1-18
Astroparticle Physics, 145, pp. 1-18
Astroparticle Physics, 145, pp. 1-18
Contains fulltext : 287339.pdf (Publisher’s version ) (Closed access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af19e6598f118197ed5377c020a426e
http://hdl.handle.net/2066/287339
http://hdl.handle.net/2066/287339
