Zobrazeno 1 - 9
of 9
pro vyhledávání: '"N. G. Ranen"'
Autor:
Anne Elizabeth Rosser, C. K. ffrench-Constant, Russell L. Margolis, John R. Hodges, J. Leggo, Christopher A. Ross, Adam Rosenblatt, Mark W. Becher, M. Sherr, M. V. Wagster, Mary L. Franz, N. G. Ranen, O. C. Stine, David C. Rubinsztein, Margaret H. Abbott
Publikováno v:
Neurology. 51:215-220
OBJECTIVE: To describe characteristics of gene-negative patients with clinical features of Huntington's disease (HD), exploring likely etiologies. BACKGROUND: When a direct gene test became definitive for diagnosis of HD, we discovered a number of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7000c0cb008002c3465e2e65fad45eaf
https://doi.org/10.1212/wnl.51.1.215
https://doi.org/10.1212/wnl.51.1.215
Publikováno v:
The Journal of Neuropsychiatry and Clinical Neurosciences. 8:338-340
Sertraline, a selective serotonin reuptake inhibitor, was used to treat two consecutive cases of genetically confirmed Huntington's disease in which severe irritability and aggressiveness required inpatient admission. The complete cessation of aggres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227fd21f871d8afdc17be4b5f059ee5c
https://doi.org/10.1176/jnp.8.3.338
https://doi.org/10.1176/jnp.8.3.338
Autor:
Elizabeth H. Aylward, Candace Young, Jason Brandt, Laura Krafft, Ann Marie Codori, Phillip R. Slavney, N G Ranen, Michael Magdalinski, Jeffrey R. Campodonico
Publikováno v:
Journal of the International Neuropsychological Society : JINS. 4(5)
Recent studies have detected basal ganglia atrophy in clinically asymptomatic persons with the genetic mutation that causes Huntington's disease (HD). Whether reductions in caudate and putamen volume on MRI scans are associated with changes in cognit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495dcc76ab2d36bd0045c774c6de5752
https://pubmed.ncbi.nlm.nih.gov/9745236
https://pubmed.ncbi.nlm.nih.gov/9745236
Autor:
M. L. Franz, P. S. Harper, Jayne Leggo, Mark W. Becher, M. Sherr, M. H. Abbott, J. C. Macmillan, L. Barron, M. Porteous, David C. Rubinsztein, O. C. Stine, M. V. Wagster, Christopher A. Ross, N. G. Ranen
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 12(4)
Dentatorubral and pallidoluysian atrophy (DRPLA) is an autosomal dominant disorder that clinically overlaps with Huntington's disease (HD) and manifests combinations of chorea, myoclonus, seizures, ataxia, and dementia. DRPLA is caused by a CAG tripl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b07c55e9cba65279fa78458c38d599c
https://pubmed.ncbi.nlm.nih.gov/9756163
https://pubmed.ncbi.nlm.nih.gov/9756163
Autor:
Susan E. Folstein, Jason Brandt, Leslie Day, Joseph T. Coyle, Carol E. Peyser, Marshal F. Folstein, M. Sherr, Christopher A. Ross, N G Ranen, Frederick W. Bylsma
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 11(5)
One hundred patients with clinically diagnosed Huntington's disease (HD) were randomized to either idebenone, an antioxidant and enhancer of oxidative metabolism, or placebo, in a 1-year, double-blind, parallel-group study aimed at slowing the rate o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca23b89bcd6d6d1d0e9c9080ec20c811
https://pubmed.ncbi.nlm.nih.gov/8866496
https://pubmed.ncbi.nlm.nih.gov/8866496
Autor:
N G, Ranen, O C, Stine, M H, Abbott, M, Sherr, A M, Codori, M L, Franz, N I, Chao, A S, Chung, N, Pleasant, C, Callahan
Publikováno v:
American journal of human genetics. 57(3)
Huntington disease (HD) is an autosomal dominant degenerative disorder caused by an expanded and unstable trinucleotide repeat (CAG)n in a gene (IT-15) on chromosome 4. HD exhibits genetic anticipation--earlier onset in successive generations within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4788d46dfa50645449f574e8af4dff45
https://pubmed.ncbi.nlm.nih.gov/7668287
https://pubmed.ncbi.nlm.nih.gov/7668287
Publikováno v:
The Journal of neuropsychiatry and clinical neurosciences. 6(2)
The authors review the records of 6 patients with Huntington's disease (HD) who received electroconvulsive therapy (ECT) for depression. Five patients met criteria for major depression and 1 for bipolar disorder, depressed. None of the patients had r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367dd880015aef5adf5ec25569d9f2aa
https://pubmed.ncbi.nlm.nih.gov/8044037
https://pubmed.ncbi.nlm.nih.gov/8044037
Autor:
Russell L. Margolis, O.C. Stine, Molly V. Wagster, W.S. Young, N G Ranen, Gabriele Schilling, M.L. Franz, Christopher A. Ross, Susan E. Folstein, Xiaohai Li, Shihua Li, John C. Hedreen, M. H. Abbott
Publikováno v:
Neuron. 11(5)
Huntington's Disease (HD) is notable for selective neuronal vulnerability in the basal ganglia and cerebral cortex. We have investigated in human and rodent tissues the expression of the gene (IT15) whose mutation causes HD. IT15 is widely expressed,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d13d4a2b18f8908387420de8deb07c
https://pubmed.ncbi.nlm.nih.gov/8240819
https://pubmed.ncbi.nlm.nih.gov/8240819
Autor:
N G Ranen
Publikováno v:
Electroencephalography and Clinical Neurophysiology. 98:227
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42cabcadb596d6daa87e5aab3eec6b22
https://doi.org/10.1016/s0013-4694(96)90292-8
https://doi.org/10.1016/s0013-4694(96)90292-8