The use of multi-domain patient reported outcome measures for detecting clinical disease progression in multiple sclerosis

Autor: Bernard M. J. Uitdehaag, E. Coerver, C. A. A. van ‘t Hullenaar, N. F. Kalkers, Z. van Kempen, Marcus W. Koch, E. M. M. Strijbis, Joep Killestein

Publikováno v: van ‘t Hullenaar, C A A, Coerver, E, Kalkers, N F, van Kempen, Z, Koch, M, Uitdehaag, B M J, Killestein, J & Strijbis, E M M 2021, ' The use of multi-domain patient reported outcome measures for detecting clinical disease progression in multiple sclerosis ', Multiple Sclerosis and Related Disorders, vol. 55, 103165 . https://doi.org/10.1016/j.msard.2021.103165
Multiple Sclerosis and Related Disorders, 55:103165. Elsevier

Objective: Patient reported outcome measures (PROMs) are especially relevant in times of increased interest in telehealth but little is known about their relation to functional disability measures. Methods: We assessed 248 people with MS at baseline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812e0b7869e35dabec86a953738064ab
https://pubmed.ncbi.nlm.nih.gov/34404022

Responder rates to fampridine differ between clinical subgroups of MS patients and patient reported outcome influences treatment decision making

Autor: N. F. Kalkers, K. H. Lam, B.M.J. Uitdehaag, C.E.P. van Munster, Joep Killestein, L. Kaya

Publikováno v: van Munster, C E P, Kaya, L, Lam, K H, Kalkers, N F, Killestein, J & Uitdehaag, B M J 2020, ' Responder rates to fampridine differ between clinical subgroups of MS patients and patient reported outcome influences treatment decision making ', Multiple Sclerosis and Related Disorders, vol. 38, 101489, pp. 101489 . https://doi.org/10.1016/j.msard.2019.101489
Multiple Sclerosis and Related Disorders, 38:101489. Elsevier

Background: Fampridine is an effective treatment to improve ambulation for some multiple sclerosis (MS) patients. Remarkable discrepancies exist between responder rates in clinical trials and the proportion of patients continuing treatment in clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849edaf756579a95e515c886867280d3
https://research.vumc.nl/en/publications/859d403a-0678-45ac-88fb-fe9a54b90f66

Differences in cognitive impairment of relapsing remitting, secondary, and primary progressive MS

Autor: I. E. W. Reuling, L.M.J. de Sonneville, V. de Groot, Chris H. Polman, N. F. Kalkers, Stephan C. J. Huijbregts

Publikováno v: Scopus-Elsevier
Huijbregts, S C J, Kalkers, N F, de Sonneville, L M J, de Groot, V, Reuling, I E W & Polman, C H 2004, ' Differences in cognitive impairment of relapsing remitting secondary and primary progressive MS ', Neurology, vol. 63, no. 2, pp. 335-339 . https://doi.org/10.1212/01.WNL.0000129828.03714.90
Huijbregts, S C J, Kalkers, N F, De Sonneville, L M J, De Groot, V, Reuling, I E W & Polman, C H 2004, ' Differences in cognitive impairment of relapsing remitting, secondary, and primary progressive MS ', Neurology, vol. 63, no. 2, pp. 335-339 . https://doi.org/10.1212/01.WNL.0000129828.03714.90
Neurology, 63(2), 335-339. American Academy of Neurology
Neurology, 63(2), 335-339. Lippincott Williams and Wilkins

Objective: To investigate the cognitive skills of patients with relapsing remitting multiple sclerosis (RRMS), secondary progressive MS (SPMS), and primary progressive MS (PPMS) relative to healthy control subjects and to assess whether there is hete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369f08e5eb2f16bec32c26bae8a8e28d
https://doi.org/10.1212/01.wnl.0000129828.03714.90

Anxiety and depression influence the relation between disability status and quality of life in multiple sclerosis

Autor: J. B. De Boer, F. G. A. Van Der Meche, P.A. van Doorn, Rogier Q. Hintzen, N. F. Kalkers, Jan Passchier, A. C. J. W. Janssens

Publikováno v: Multiple Sclerosis, 9, 397-403. SAGE Publications Ltd

Disability status, depression and anxiety are important determinants of quality of life (Q oL) in patients with multiple sclerosis (MS). We investigated whether anxiety and depression influence the relation between disability status and Q oL in our c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4246f6ab2aa352b2fa4293aaf219b87e
https://hdl.handle.net/1765/70533

Brain atrophy in multiple sclerosis

Autor: N. F. Kalkers, B.M.J. Uitdehaag, H. Vrenken, Chris H. Polman, Frederik Barkhof

Publikováno v: Multiple Sclerosis, 8(5), 410-414. SAGE Publications
Kalkers, N F, Vrenken, H, Uitdehaag, B M J, Polman, C H & Barkhof, F 2002, ' Brain atrophy in multiple sclerosis : Impact of lesions and of damage of whole brain tissue ', Multiple Sclerosis, vol. 8, no. 5, pp. 410-414 . https://doi.org/10.1191/1352458502ms833oa

Introduction: In multiple sclerosis (MS), brain atrophy measurement on magnetic resonance imaging (MRI) reflects overall tissue loss, especially demyelination and axonal loss. We studied which factor contributes most to the development of brain atrop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edb41e8a4e2db32894e3814c9140589
https://doi.org/10.1191/1352458502ms833oa