Zobrazeno 1 - 10
of 29
pro vyhledávání: '"N. Ekwuribe"'
Autor:
Kenneth D. James, Nnochiri N. Ekwuribe
Publikováno v:
Tetrahedron. 58:5905-5908
The racemic antiandrogen bicalutamide is the leading antiandrogen used for the treatment of prostate cancer. The (R)-isomer possesses virtually all of the activity, but both isomers are metabolized by the liver. A convenient synthetic route to the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5d4f030ffc22ce82a64d34eda9cbaaa
https://doi.org/10.1016/s0040-4020(02)00560-4
https://doi.org/10.1016/s0040-4020(02)00560-4
Autor:
Nnochiri N. Ekwuribe, Kenneth D. James
Publikováno v:
Synthesis. 2002:850-852
A short, efficient synthesis of the non-steroidal antiandrogen (R,S)-bicalutamide is presented. This new route generates bicalutamide in only two steps with an overall yield of 73%. The key step is a 1,2 addition of a methyl sulfone to a keto-amide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e608f4d89f63a1de4363888e9f16d1e
https://doi.org/10.1055/s-2002-28508
https://doi.org/10.1055/s-2002-28508
Autor:
Nnochiri N. Ekwuribe, Kenneth D. James
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061d9a22b1328d1c17bef7bd2e9dcc89
https://doi.org/10.1002/chin.200239092
https://doi.org/10.1002/chin.200239092
Autor:
Rodger A. Liddle, Nnochiri N. Ekwuribe, Steven R. Vigna, D. C. McVey, Jennifer Riggs-Sauthier
Publikováno v:
Digestive diseases and sciences. 50(3)
A new compound, APAZA, consisting of a molecule of 5-aminosalicylic acid linked to one molecule of 4-aminophenylacetic acid by an azo bond, was testedfor its ability to inhibit acute colitis in rats caused by Clostridium difficile toxin A. When admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9c1e5b175845b2c825cd1c6bb0bef8
https://pubmed.ncbi.nlm.nih.gov/15810644
https://pubmed.ncbi.nlm.nih.gov/15810644
Autor:
John A. Schirger, John C. Burnett, Kenneth D. James, Mark A. Miller, Fernando L. Martin, Alessandro Cataliotti, Navdeep B. Malkar, Nnoch N. Ekwuribe, Horng H. Chen
Publikováno v:
American Journal of Hypertension. 18:A247-A247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4dd0fe6b40c242ca7e25a8c9db36b4a
https://doi.org/10.1016/j.amjhyper.2005.03.674
https://doi.org/10.1016/j.amjhyper.2005.03.674
Autor:
E. Giuffr, Lorenzo Malatino, P. Belluardo, G. Raspa, J. C. Burnett, N. N. Ekwuribe, L. Bonaiuto, M. A. Miller, H. H. Chen, P. Noto, Kenneth D. James, J. A. Schirger, E. Maugeri, Cataliotti, G. Orlando
Publikováno v:
High Blood Pressure & Cardiovascular Prevention. 12:164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f547079a41b76c1d51be660279c85404
https://doi.org/10.2165/00151642-200512030-00059
https://doi.org/10.2165/00151642-200512030-00059
Autor:
Lisa C. Costello-Boerrigter, Guido Boerrigter, Alessandro Cataliotti, Nnoch N. Ekwuribe, Horng H. Chen, John C. Burnett, Kenneth D. James, Navdeep B. Malkar, Mark A. Miller, John A. Schirger, Fernando L. Martin
Publikováno v:
Journal of Cardiac Failure. 10:S47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8488b6222846ee42fb577cae870dfbc1
https://doi.org/10.1016/j.cardfail.2004.06.103
https://doi.org/10.1016/j.cardfail.2004.06.103
Publikováno v:
The Journal of Organic Chemistry. 47:4341-4344
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be586d0012f789ee8eaf4f76684de4ec
https://doi.org/10.1021/jo00143a035
https://doi.org/10.1021/jo00143a035
Publikováno v:
Tetrahedron Letters. 20:4025-4028
The novel thermolytic rearrangement of prop-2-ynyl N-Oxides to hydroxylamine O-allenyl ethers has been examined by deuterium labeling. Product analysis by gc-eims and by cims has shown the reaction to proceed by a concerted cyclic transition state.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc4f6b0714b1164e93b7acefa2d0ed27
https://doi.org/10.1016/s0040-4039(01)86494-7
https://doi.org/10.1016/s0040-4039(01)86494-7
Autor:
Robert J. Linhardt, E. A. Balazs, D. J. Wedlock, G. O. Phillips, A. Leshchiner, R. S. Langer, R. J. Linhardt, C. L. Cooney, G. Fitzgerald, A. Grant, S. E. Lasker, J. C. Lormeau, J. Choay, J. Goulay, M. T. Goulay-Heir, M. A. Goulay-Heir, G. Goulay-Heir, M. Petitou, D. B. Soll, S. E. Harrison, L. L. Teng, A. G. Walton, R. V. Sparer, N. Ekwuribe, J. K. Borchardt, J. W. Bracke, K. Thacker, P. Brocklehurst, A. S. Ferguson, L. K. Gordon, H. Hayes, S. Inoue, H. Yamamoto, A. M. Nonomura, R. Pappo, J. M. Schweid, A. H. Cohee, A. F. Dec, L. K. Shay, S. E. Reiter, L. Turrisi, I. Umezawa, K. Komiyama, D. Williams, D. M. Munnecke, R. T. Zahradnik, K. Arizono, M. Terasawa, M. Nobutoki, L. C. A. Bergwitz, R. G. L. Osterlund, C. Brain, B. Johnston, L. G. Brooker, T. S. Chang, L. J. Zientek, A. Viniguaz, I. Chibata, T. Tosa, S. Takamatsu, D. F. Doehnert, A. S. Hill, D. P. Gaehring, J. V. Scanlon, G. D. Hansen, K. M. E. Hellsten, R. L. Horion, R. B. Kennedy, R. S. Kohn, A. J. Kruger, J. K. Johnson, W. Y. Kuu, V. K. Larsson, J. F. Mezzino, L. Y. Chuang, J. Michnowski, Y. Miyashiro, M. Ogawa, Y. Yamazaki, S. Igarasi, K. Morimoto, S. Nochumson, M. A. Pellico, R. J. Purinton, F. Reinhardt, K. Sakata, H. Imai, A. J. Sensabaugh, D. C. Crepps, W. Y. Rice, G. W. Fearrington, J. L. Shim, Y. Shimohiro, T. Ohnishi, E. Simon, H. Stuhler, E. Krempl, D. T. Su, K. Szendrei, E. Minker, Z. Re, L. Koch, L. Wolf, E. Szijj, M. Re, M. Trop, D. C. Tunc, T. Ueda, M. Vellini, R. B. Wallace, K. Watanabe, S. Yoshikawa, S. Futami, R. H. Wunder
Publikováno v:
Applied Biochemistry and Biotechnology. 12:177-197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85e331276b6ca19c54786cc792be5bad
https://doi.org/10.1007/bf02798421
https://doi.org/10.1007/bf02798421