Zobrazeno 1 - 10
of 110
pro vyhledávání: '"N. E. Kuz'Mina"'
Publikováno v:
Безопасность и риск фармакотерапии, Vol 12, Iss 3, Pp 352-360 (2024)
INTRODUCTION. This work continues the authors’ earlier study on gelatine capsule contamination with elemental impurities, which resulted in proposing a list of elements for standardisation. To ensure the safe use of medicinal products in this dosag
Externí odkaz:
https://doaj.org/article/b07df57a9a314a898e37d8a27a8fc8bf
Publikováno v:
Безопасность и риск фармакотерапии, Vol 12, Iss 2, Pp 230-240 (2024)
INTRODUCTION. Gelatine capsules are an essential dosage form used for many medicinal products. Gelatine capsules are subject to quality control in accordance with the requirements of the general monograph on capsules of the State Pharmacopoeia of the
Externí odkaz:
https://doaj.org/article/e31fef8c1b1f421eb55058f4a7914402
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 4, Pp 578-585 (2023)
Scientific relevance. Hypromellose phthalate is a component of enteric coatings used to modify active substance release from oral medicinal products in the small intestine. The release rate directly depends on the non-stoichiometric composition of th
Externí odkaz:
https://doaj.org/article/7d2a36939aac476a926fb266eacaef3d
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 3, Pp 403-410 (2023)
Scientific relevance. Zinc quantification in insulin active substances and preparations by atomic absorption spectrometry requires a sample preparation procedure using hydrochloric acid, a narcotic and psychotropic precursor. The exclusion of precurs
Externí odkaz:
https://doaj.org/article/38b472db14ad46658470955801ccd1dd
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 3, Pp 433-441 (2023)
Scientific relevance. Laminariae thalli are a native herbal preparation used to prevent or treat multiple diseases. To achieve the optimal effect, this herbal preparation is usually taken for several weeks or months. The control of Laminariae thalli
Externí odkaz:
https://doaj.org/article/792fa7c0bff5497b89899336e34190e7
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 3, Pp 394-402 (2023)
Scientific relevance. Zinc content is a quality attribute of insulin products. The State Pharmacopoeia of the Russian Federation requires that it should be determined by flame atomic absorption spectrometry (FAAS). However, many pharmaceutical manufa
Externí odkaz:
https://doaj.org/article/66dbf859792942679a148519eeb451f9
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 3, Pp 385-393 (2023)
Scientific relevance. Hypromellose phthalate is used in enteric coatings for oral medicinal products. The proportion of phthalate groups in the polymer is standardised because it has a significant effect on solubility. Whereas, the molecular mass of
Externí odkaz:
https://doaj.org/article/7825b42082a24a59acff8c71688c56d7
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 2-1, Pp 283-291 (2023)
Gentamicin sulfate is a broad-spectrum bactericidal aminoglycoside antibiotic produced by Micromonospora purpurea and used in clinical practice as an active substance containing a mixture of gentamicins C1 and C2. Gentamicin content is a standardised
Externí odkaz:
https://doaj.org/article/75457c13cba246b387d95fa761141c97
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 2, Pp 206-215 (2023)
Kelp can accumulate large quantities of arsenic compounds even in the absence of considerable environmental pollution. A substantial difference in toxicity between organic and inorganic arsenic compounds makes the form of arsenic relevant for the ris
Externí odkaz:
https://doaj.org/article/1169ab3a1c7f4aff88a460d2589a141d
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 2, Pp 154-172 (2023)
Brown seaweeds (Laminariaceae) vary considerably in the content of toxic and essential elements; these variations depend on the taxonomic group and geographical factors. Seaweeds are extensively used in the food industry and widely applied in medicin
Externí odkaz:
https://doaj.org/article/fde1e7d941d54b7dbd40d331d5621dcc