Výsledky vyhledávání - "N. Dayanthi Perera"

Akademický článek

Oxidative stress differentially impacts apical and basolateral secretion of angiogenic factors from human iPSC-derived retinal pigment epithelium cells

Autor: Lisheng Chen, N. Dayanthi Perera, Athanasios J. Karoukis, Kecia L. Feathers, Robin R. Ali, Debra A. Thompson, Abigail T. Fahim

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract The retinal pigment epithelium (RPE) is a polarized monolayer that secretes growth factors and cytokines towards the retina apically and the choroid basolaterally. Numerous RPE secreted proteins have been linked to the pathogenesis of age-re

Externí odkaz: https://doaj.org/article/6ff88f32799141fea6e94fdb2912f7c1

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Detailed clinical characterisation, unique features and natural history of autosomal recessive RDH12-associated retinal degeneration

Autor: N Dayanthi Perera, Kari H. Branham, Robin R. Ali, Mark E. Pennesi, Abigail T. Fahim, Michel Michaelides, Neruban Kumaran, John R. Heckenlively, Debra A. Thompson, Kecia L. Feathers, Zaina Ibrahim Bouzia, Mauricio E Vargas, Andrew R. Webster, Kelly Z. Young, Naheed W. Khan

Publikováno v: British Journal of Ophthalmology. :bjophthalmol-2018

BackgroundDefects in retinol dehydrogenase 12 (RDH12) account for 3.4%–10.5 % of Leber congenital amaurosis and early-onset severe retinal dystrophy (EOSRD) and are a potential target for gene therapy. Clinical trials in inherited retinal diseases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b72912521f6cdc023a3b24f8dd3c3636
https://doi.org/10.1136/bjophthalmol-2018-313580

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