Apolipoprotein M and Risk of Type 2 Diabetes

Autor: Anne Tybjærg-Hansen, Christina Christoffersen, N. Dalila, Stefan Hajny, M. Christoffersen, Lars Nielsen

Publikováno v: Hajny, S, Christoffersen, M, Dalila, N, Nielsen, L B, Tybjærg-Hansen, A & Christoffersen, C 2020, ' Apolipoprotein M and Risk of Type 2 Diabetes ', Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 9, pp. 3046-3057 . https://doi.org/10.1210/clinem/dgaa433

Context Recent studies have discovered a role of apolipoprotein M (apoM) in energy metabolism, and observational analyses in humans suggest an association with type 2 diabetes. The causal relationship remains however elusive. Objective To investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cdf54d9dc050ae2413fcf569ed9fae
https://doi.org/10.1210/clinem/dgaa433

Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome

Autor: Joel T. Haas, Jan Albert Kuivenhoven, Justina C. Wolters, Andrzej J. Rzepiela, Mathilde Varret, Ann Verhaegen, Valérie Carreau, Szymon Stoma, Anne Philippi, Alaa Othman, Jerome Robert, N. Dalila, Belle V. van Rosmalen, An Verrijken, Arnold von Eckardstein, Bart van de Sluis, Silvija Radosavljevic, Paolo Zanoni, Simon F. Norrelykke, Roger Meier, M. Yalcinkaya, Bart Staels, Andreas Geier, Lucia Rohrer, Michael Stebler, Michele Visentin, Antoine Rimbert, Catherine Boileau, Antonio Gallo, Melinde Wijers, Nicolette C. A. Huijkman, Steve E. Humphries, Jonas Weyler, Freerk van Dijk, Michaela Keel, Srividya Velagapudi, Jean-Pierre Rabès, Marieke Smit, Anne Tybjærg-Hansen, Adriaan van der Graaf, Luisa Vonghia, Yara Abou-Khalil, Sven Francque, Grigorios Panteloglou, Marta Futema, Luc Van Gaal

Publikováno v: Zanoni, P, Panteloglou, G, Othman, A, Haas, J T, Meier, R, Rimbert, A, Futema, M, Khalil, Y A, Norrelykke, S F, Rzepiela, A J, Stoma, S, Stebler, M, Van Dijk, F, Wijers, M, Wolters, J C, Dalila, N, Huijkman, N C A, Smit, M, Gallo, A, Carreau, V, Philippi, A, Rabès, J P, Boileau, C, Visentin, M, Vonghia, L, Weyler, J, Francque, S, Verrijken, A, Verhaegen, A, Van Gaal, L, Van Der Graaf, A, Van Rosmalen, B V, Robert, J, Velagapudi, S, Yalcinkaya, M, Keel, M, Radosavljevic, S, Geier, A, Tybjaerg-Hansen, A, Varret, M, Rohrer, L, Humphries, S E, Staels, B, Van De Sluis, B, Kuivenhoven, J A & Von Eckardstein, A 2022, ' Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome ', Circulation Research, vol. 130, no. 1, pp. 80-95 . https://doi.org/10.1161/CIRCRESAHA.120.318141
Circulation Research
Circulation Research, 2022, 130 (1), pp.80-95. ⟨10.1161/CIRCRESAHA.120.318141⟩
Circulation research
Circulation research, 130(1), 80-95. LIPPINCOTT WILLIAMS & WILKINS

Background: The LDLR (low-density lipoprotein receptor) in the liver is the major determinant of LDL-cholesterol levels in human plasma. The discovery of genes that regulate the activity of LDLR helps to identify pathomechanisms of hypercholesterolem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7252f24e599e74af7d4245ca33b8f0
https://curis.ku.dk/portal/da/publications/posttranscriptional-regulation-of-the-human-ldl-receptor-by-the-u2spliceosome(80ba810e-1e80-4fb5-8616-1532e1482dba).html

Identification and Replication of Six Loci Associated With Gallstone Disease

Autor: Helene Gellert‐Kristensen, Sune Fallgaard Nielsen, Stefan Stender, Anne Tybjærg-Hansen, N. Dalila, Børge G. Nordestgaard

Publikováno v: Hepatology. 70:597-609

Gallstone disease is a common complex disease that confers a substantial economic burden on society. The genetic underpinnings of gallstone disease remain incompletely understood. We aimed to identify genetic associations with gallstone disease using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb30580212cc2b8286b82ed6fe99b1d
https://doi.org/10.1002/hep.30313

Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans

Autor: Bart van de Sluis, Geesje M. Dallinga-Thie, Richard J. Sinke, Federico Oldoni, N. Dalila, Jan Albert Kuivenhoven, Justina C. Wolters, Julian C. van Capelleveen, David Y. Hui, Joerg Heeren, Kees Hovingh, Ruth Frikke-Schmidt, Anne Tybjærg-Hansen

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology, 38(7), 1440-1453. Lippincott Williams and Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, thrombosis, and vascular biology, 38(7), 1440-1453. LIPPINCOTT WILLIAMS & WILKINS

Supplemental Digital Content is available in the text.
Objective— Studies into the role of LRP1 (low-density lipoprotein receptor–related protein 1) in human lipid metabolism are scarce. Although it is known that a common variant in LRP1 (rs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611b23945be51ee53072762048899bc5
https://doi.org/10.1161/atvbaha.117.310309

Molybdenum Disulfide (MoS2)/Gold Nanoparticles (AuNPs)-based Field-effect Transistor for C-reactive Protein Detection: Early Diagnosis of Cardiovascular Disease

Autor: N. Dalila R., M. K. Md Arshad, Subash C. B. Gopinath, M. Nuzaihan M. N., C. Ibau, Iswary Letchuman

Publikováno v: 2019 IEEE International Conference on Sensors and Nanotechnology.

C-reactive protein (C-RP), a biomarker for inflammatory validation associated with cardiovascular disease (CVD). Major infection or severe trauma trigger the activation of this protein in the patient's blood. In this paper, the conventional field-eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::369c459883963e3c6e9dbecf8d79e4c4
https://doi.org/10.1109/sensorsnano44414.2019.8940056