Zobrazeno 1 - 10
of 15
pro vyhledávání: '"N. Craig Goodman"'
Autor:
Denis J. Meerdink, David K. Glover, N. Craig Goodman, Joel Linden, George A. Beller, Rajan A. G. Patel, Alexis Broisat, Mirta Ruiz, Hasan K. Kabul, Christopher M. Kramer
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 297:H637-H642
This study was undertaken to determine whether the myocardial infarct-sparing effect of ATL-146e, a selective adenosine A2A receptor agonist, persists without a rebound effect for at least 48 h and to determine the optimal duration of ATL-146e treatm
Autor:
Sanjiv Kaul, Marco Pascotto, Ananda R. Jayaweera, N. Craig Goodman, Antonio Micari, Jiri Sklenar
Publikováno v:
Journal of Ultrasound in Medicine. 25:1009-1019
OBJECTIVE We tested the hypothesis that the cyclic variation in ultrasonic myocardial integrated backscatter (IBS) is due to cardiac contraction-induced changes in the number of patent myocardial microvessels. METHODS We performed experiments in open
Publikováno v:
Journal of the American College of Cardiology. 40(1):167-174
ObjectivesWe hypothesized that, although the effects of dipyridamole and dobutamine on myocardial blood volume (MBV) and mean microbubble velocity (VEL) are different, the magnitude of perfusion deficit during both forms of stress is the same because
Autor:
Elizabeth Le, Sanjiv Kaul, William D. Spotnitz, Robert A. Pelberg, Jian Ping Bin, N. Craig Goodman
Publikováno v:
Journal of the American Society of Echocardiography. 14:1047-1056
In chronic coronary artery disease, resting myocardial dysfunction can exist despite normal resting transmural myocardial blood flow (MBF). We hypothesized that this phenomenon occurs because of diminished endocardial MBF reserve. MBF (measured with
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 279:H3058-H3064
In the setting of chronic coronary stenoses, percent wall thickening (%WT) both at rest and during catecholamine stimulation can be abnormal despite normal resting myocardial blood flow (MBF). We hypothesized that this phenomenon is related to abnorm
Publikováno v:
The Journal of Arthroplasty. 14:481-487
The spray application of cryo-based fibrin sealant was evaluated for reducing hemorrhage in a complex, anticoagulated canine model of knee joint arthroplasty. Nine heparinized dogs underwent bilateral knee arthroplasty under tourniquet control with e
Autor:
N. Craig Goodman, Gustavo Camarano, Ananda R. Jayaweera, Jiri Sklenar, Suad Ismail, Sanjiv Kaul
Publikováno v:
Circulation. 94:1430-1440
Background We hypothesized that microvascular reserve is a better indicator of the extent of viable myocardium postinfarction than contractile reserve, especially in the presence of a residual stenosis of the infarct-related artery. Methods and Resul
Autor:
N. Craig Goodman, Jian Ping Bin, Howard Leong-Poi, Sanjiv Kaul, D. Elizabeth Le, Eric R. Powers
Publikováno v:
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 14(2)
Background The mechanism by which transmyocardial revascularization (TMR) offers clinical benefit is controversial. We hypothesized that TMR ameliorates ischemia by reversing paradoxical catecholamine-induced vasoconstriction. Methods and Results Chr
Publikováno v:
Circulation. 105(2)
Background — Currently, the detection of noncritical coronary stenoses requires some form of stress. We hypothesized that these stenoses can be detected at rest without recourse to stress by assessing adaptive changes that occur distally in the mic
Publikováno v:
The American journal of physiology. 276(2)
The controversy regarding the mechanism(s) of left ventricular (LV) dysfunction in chronic coronary artery disease is, in part, related to the lack of an appropriate animal model for this condition. We have developed such a model by placing Ameroid c