Zobrazeno 1 - 10
of 29
pro vyhledávání: '"N. Cosma"'
Autor:
A. Nemali, N. Vockert, D. Berron, A. Maas, R. Yakupov, O. Peters, D. Gref, N. Cosma, L. Preis, J. Priller, E. Spruth, S. Altenstein, A. Lohse, K. Fliessbach, O. Kimmich, I. Vogt, J. Wiltfang, N. Hansen, C. Bartels, B.H. Schott, F. Maier, D. Meiberth, W. Glanz, E. Incesoy, M. Butryn, K. Buerger, D. Janowitz, M. Ewers, R. Perneczhy, B. Rauchmann, L. Burow, S. Teipel, I. Kilimann, D. Göerß, M. Dyrba, C. Laske, M. Munk, C. Sanzenbacher, S. Müller, A. Spottke, N. Roy, M. Heneka, F. Brosseron, S. Roeske, L. Dobisch, A. Ramirez, P. Dechent, K. Scheffler, L. Kleineidam, S. Wolfsgruber, M. Wagner, F. Jessen, E. Duzel, G. Ziegler
Neuroimaging markers based on Magnetic Resonance Imaging (MRI) combined with various other measures (such as informative covariates, vascular risks, brain activity, neuropsychological test etc.,) might provide useful predictions of clinical outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb8ed193a1004a3a8eac9bbc48252c3
https://doi.org/10.1101/2022.03.14.484226
https://doi.org/10.1101/2022.03.14.484226
Akademický článek
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Akademický článek
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Autor:
Gregory N. Cosma, William E. Achanzar, Jiangyue Wu, Lauro Minimo, Carolyn F. Moyer, Mark S. Kirby, Mark D. Gorrell, Nicole D. Ordway, Laura Rosini-Marthaler, Russell Gullo, Kristina D. Chadwick, Eric. B. Harstad, Jonathan S. Rosenblum
Publikováno v:
Regulatory Peptides. 186:26-35
Dipeptidyl peptidases (DPPs) are proteolytic enzymes that regulate many physiological systems by degrading signaling peptides. DPP8 and DPP9 are distinct from DPP4 in sequence, cellular localization and expression levels, thus implying distinct funct
Autor:
George G. Harrigan, Glenn H. Cantor, Gary L. Cockerell, Robert A. Roth, Patricia E. Ganey, Roy H. Bible, Gregory N. Cosma, James P. Luyendyk, Alan P. Breau, Jane F. Maddox, Royston Goodacre
Publikováno v:
Toxicology and Applied Pharmacology. 212:35-44
Idiosyncratic liver injury occurs in a small fraction of people on certain drug regimens. The cause of idiosyncratic hepatotoxicity is not known; however, it has been proposed that environmental factors such as concurrent inflammation initiated by ba
Autor:
Robert A. Roth, Gregory N. Cosma, William B. Mattes, Lyle D. Burgoon, Patricia E. Ganey, James P. Luyendyk, Timothy R. Zacharewski, Jane F. Maddox
Publikováno v:
Toxicological Sciences. 80:203-213
Studies in rats have demonstrated that modest underlying inflammation can precipitate idiosyncratic-like liver injury from the histamine 2-receptor antagonist, ranitidine (RAN). Coadministration to rats of nonhepatotoxic doses of RAN and the inflamma
Publikováno v:
European Neuropsychopharmacology. 24:S194-S195
Autor:
Gregory N. Cosma, Mark A. Dominick, John C. Kozlosky, William E. Achanzar, Carolyn F. Moyer, Russell Gullo, James W. Rhodes, Bruce D. Car, James J. Burgun, Laura T. Marthaler, Michele H. French, Linda Watson, Melvin R. White, William R. Foster, Shen-Jue Chen
Publikováno v:
Toxicology and applied pharmacology. 223(3)
We previously reported prevention of urolithiasis and associated rat urinary bladder tumors by urine acidification (via diet acidification) in male rats treated with the dual peroxisome proliferator-activated receptor (PPAR)alpha/gamma agonist muragl
Autor:
Royston Goodacre, Roxanne H LaPlante, Greg N Cosma, George G. Harrigan, James P. Luyendyk, Jane F. Maddox, Patricia E. Ganey, Gary L. Cockerell, Robert A. Roth
Publikováno v:
Toxicology letters. 146(3)
An evaluation of high-throughput Fourier-transform infrared spectroscopy (FT-IR) as a technology that could support a "metabonomics" component in toxicological studies of drug candidates is presented. The hypothesis tested in this study was that FT-I
Autor:
Robert A. Roth, Gregory N. Cosma, Patricia E. Ganey, Gary L. Cockerell, Jane F. Maddox, James P. Luyendyk
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 307(1)
Drug idiosyncrasy is an adverse event of unknown etiology that occurs in a small fraction of people taking a drug. Some idiosyncratic drug reactions may occur from episodic decreases in the threshold for drug hepatotoxicity. Previous studies in rats