Zobrazeno 1 - 10
of 23
pro vyhledávání: '"N. Catherine Hogan"'
Publikováno v:
Journal of Controlled Release. 258:73-80
Intradermal immunization of mice against hepatitis B surface antigen (HBsAg) using a novel real-time controlled jet injector was assessed by comparison with intradermal and subcutaneous injection of antigen using a 27G needle and syringe. Three doses
Autor:
Andrew J. Taberner, Poul M. F. Nielsen, N. Catherine Hogan, Rhys M. J. Williams, Ian W. Hunter, Bryan P. Ruddy
Publikováno v:
IEEE Transactions on Biomedical Engineering. 63:1099-1106
Objective: A jet injector is a device that can be used to deliver liquid drugs through the skin using a fluid jet, without the use of a needle. Most jet injectors are designed and used for the delivery of inviscid liquids, and are not optimized for t
Autor:
Poul M. F. Nielsen, Ian W. Hunter, James W. McKeage, Kieran A. Brennan, Bryan P. Ruddy, Andrew J. Taberner, N. Catherine Hogan, Geehoon Park
Publikováno v:
EMBC
The effect of varying velocity during jet injection on the dispersion of fluid into tissue is investigated using a custom-built X-ray imaging system. Injections are performed into ex-vivo porcine abdominal tissue using a voice coil actuated injection
Publikováno v:
EMBC
A rigid, compact, multi-piece ampoule has been designed and fabricated as a platform to conveniently house different nozzle inserts one at a time to offer increased jet consistency and functional flexibility. Three different nozzle geometries that re
Publikováno v:
EMBC
Controllable jet injection could provide a fast, repeatable method for delivery of small volume, high viscosity drugs to the dermis. We have developed a compact, lightweight jet injector that uses a small commercial rotary motor and differential scre
Publikováno v:
EMBC
The effects of the dispersion pattern of a needle-free jet injector are explored. The shape of the jets were compared using a high-speed video camera and jet injections of collimated and dispersed fluid jets with a Lorentz-force actuated jet injector
Publikováno v:
EMBC
A nonlinear, sliding mode adaptive controller was created for a needle-free jet injection system. The controller was based on a simplified lumped-sum parameter model of the jet-injection mechanics. The adaptive control scheme was compared to a curren
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 211
We present a novel method of quickly acquiring dermal interstitial fluid (ISF) samples using a Lorentz-force actuated needle-free jet injector. The feasibility of the method is first demonstrated on post-mortem porcine tissue. The jet injector is use
Publikováno v:
Analytical Chemistry. 77:5129-5134
We have developed an instrument for monitoring real-time PCR using fluorescence anisotropy, enabling an assay chemistry in which the fluorescence from a labeled primer elucidates amplification. The instrument holds the sample temperature constant to
Publikováno v:
ISBI