Zobrazeno 1 - 10
of 10
pro vyhledávání: '"N. C. Luetteke"'
Autor:
Eric P. Sandgren, D. C. Lee, Richard D. Palmiter, Ralph L. Brinster, N. C. Luetteke, Ting Hu Qiu
Publikováno v:
Molecular and Cellular Biology. 13:320-330
To characterize the effect(s) of transforming growth factor alpha (TGF alpha) during multistage carcinogenesis, we examined tumor development in pancreas and liver of transgenic mice that coexpressed TGF alpha with either viral (simian virus 40 T ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96369e9bd744f09949927e426f0182d8
https://doi.org/10.1128/mcb.13.1.320-330.1993
https://doi.org/10.1128/mcb.13.1.320-330.1993
Autor:
K G Nelson, K Ross, D C Lee, Nancy L. Bossert, B E Eitzman, N C Luetteke, John A. McLachlan, Tsuneo Takahashi
Publikováno v:
Endocrinology. 131:1657-1664
To better understand the role of peptide growth factors in sex steroid hormone-mediated growth of the female reproductive tract, the effect of estrogen on the expression of transforming growth factor-alpha (TGF alpha) in mouse uterus was investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8954b21cb0cfebda75349693494ca7ef
https://doi.org/10.1210/endo.131.4.1396310
https://doi.org/10.1210/endo.131.4.1396310
Autor:
E A, Berkowitz, K B, Seroogy, J A, Schroeder, W E, Russell, E P, Evans, R F, Riedel, H K, Phillips, C A, Harrison, D C, Lee, N C, Luetteke
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(9)
The spontaneous mouse waved 1 (wa1) mutation is allelic with the transforming growth factor alpha (TGF-alpha) gene and produces phenotypes similar to those of TGF-alpha knockout mice. Here, we show that TGF-alpha mRNA and protein levels are measurabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e083164b8833c3aacf01034ada81e69
https://pubmed.ncbi.nlm.nih.gov/8877107
https://pubmed.ncbi.nlm.nih.gov/8877107
Publikováno v:
Molecular carcinogenesis. 15(3)
Transforming growth factor-alpha (TGF alpha), a member of the epidermal growth factor receptor ligand family, has been implicated in the regeneration and transformation of liver. Our recent development of mice that are homozygous for a disrupted TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d1031d47a0ab51d146b057e40063d6d
https://pubmed.ncbi.nlm.nih.gov/8597531
https://pubmed.ncbi.nlm.nih.gov/8597531
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 4(3)
Transgenic mice overexpressing transforming growth factor alpha (TGF-alpha) under control of the metallothionein promoter had, on average, 20% reductions in body and carcass weights compared to nontransgenic littermates. This loss resulted from signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b780dfb3b1fd14c74a3becd208aff21
https://pubmed.ncbi.nlm.nih.gov/8466858
https://pubmed.ncbi.nlm.nih.gov/8466858
To characterize the effect(s) of transforming growth factor alpha (TGF alpha) during multistage carcinogenesis, we examined tumor development in pancreas and liver of transgenic mice that coexpressed TGF alpha with either viral (simian virus 40 T ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8984cf89898117d520cc2b9ee7fb7b2
Publikováno v:
Cancer treatment and research. 63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea5774544f124ede29e2ede1533804fc
https://pubmed.ncbi.nlm.nih.gov/1363359
https://pubmed.ncbi.nlm.nih.gov/1363359
Autor:
N C, Luetteke, D C, Lee
Publikováno v:
Seminars in cancer biology. 1(4)
Transforming growth factor alpha (TGF alpha) is a 6 kDa polypeptide mitogen that interacts with the epidermal growth factor receptor and activates its intrinsic tyrosine kinase. The mature 50 amino acid TGF alpha is released from a 159 or 160 amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6cb401a9697914776b75c61e5008c92
https://pubmed.ncbi.nlm.nih.gov/2103501
https://pubmed.ncbi.nlm.nih.gov/2103501
Publikováno v:
Oncogene. 5(8)
TGF alpha is one member of a family of soluble growth factors that are derived from integral-membrane precursors. The mature form of TGF alpha is released from its transmembrane precursor (proTGF alpha) by a protease that, in many tumor cells, is ine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b60661312705d819c1e8fc1652784eb3
https://pubmed.ncbi.nlm.nih.gov/2392325
https://pubmed.ncbi.nlm.nih.gov/2392325
Autor:
N C, Luetteke, G K, Michalopoulos
Publikováno v:
Cancer research. 45(12 Pt 1)
Serum-free medium conditioned by confluent cultures of JM1 of JM2 rat hepatocellular carcinoma cells stimulated DNA synthesis in primary cultures of adult rat hepatocytes in a dose-dependent, saturable manner and in the absence of epidermal growth fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4a50529b9841d3f28c2cc4e1da6552b
https://pubmed.ncbi.nlm.nih.gov/2998598
https://pubmed.ncbi.nlm.nih.gov/2998598