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Isolation, structure, and functional elucidation of a modified pentapeptide, cysteine protease inhibitor (CPI-2081) from Streptomyces species 2081 that exhibit inhibitory effect on cancer cell migration

Autor: P. R. Rajamohanan, Gopal C. Kundu, Sushma Gaikwad, N. C. Jima, Goutam Chakraborty, Sudarsan Tamang, Mohamad I. Khan, Jay Prakash Singh

Publikováno v: Journal of medicinal chemistry. 53(14)

Cysteine proteases play an important role in cell migration and tumor metastasis. Therefore, their inhibitors are of colossal interest, having potential to be developed as effective antimetastatic drugs for tumor chemotherapy. Traditionally, secondar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87240fc9515527a6f1c399380e878653
https://pubmed.ncbi.nlm.nih.gov/20552970

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Akademický článek

Isolation, Structure, and Functional Elucidation of a Modified Pentapeptide, Cysteine Protease Inhibitor (CPI-2081) from Streptomyces Species2081 that Exhibit Inhibitory Effect on Cancer Cell Migration.

Autor: Jay Prakash Singh, Sudarsan Tamang, P. R. Rajamohanan, N. C. Jima, Goutam Chakraborty, Gopal C. Kundu, Sushma M. Gaikwad, Mohamad I. Khan

Publikováno v: Journal of Medicinal Chemistry; Jul2010, Vol. 53 Issue 14, p5121-5128, 8p

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