Zobrazeno 1 - 10
of 105
pro vyhledávání: '"N. Butterfield"'
Autor:
Daniela S. Aliaga Goltsman, Lisa M. Alexander, Jyun-Liang Lin, Rodrigo Fregoso Ocampo, Benjamin Freeman, Rebecca C. Lamothe, Andres Perez Rivas, Morayma M. Temoche-Diaz, Shailaja Chadha, Natalie Nordenfelt, Owen P. Janson, Ian Barr, Audra E. Devoto, Gregory J. Cost, Cristina N. Butterfield, Brian C. Thomas, Christopher T. Brown
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Programmable, RNA-guided nucleases are diverse enzymes that have been repurposed for biotechnological applications. Here, the authors mine an extensive genome-resolved metagenomics database and identified uncharacterized families of RNA-guided, compa
Externí odkaz:
https://doaj.org/article/7663af1aa1e14736809578ccd16ebe1a
Autor:
John J. Millichap, Cynthia L. Harden, Dennis J. Dlugos, Jacqueline A. French, Noam N. Butterfield, Celene Grayson, Ernesto Aycardi, Simon N. Pimstone
Publikováno v:
Epilepsia Open, Vol 6, Iss 1, Pp 38-44 (2021)
Abstract Literature review of patients with KCNQ2 developmental and epileptic encephalopathy (KCNQ2‐DEE) reveals, based on 16 reports including 139 patients, a clinical phenotype that includes age‐ and disease‐specific stereotyped seizures. The
Externí odkaz:
https://doaj.org/article/19ac3bfee377407aa43fcd3590325a6b
Autor:
Rebecca C. Lamothe, Meghan D. Storlie, Diego A. Espinosa, Rachel Rudlaff, Patrick Browne, Jason Liu, Andres Rivas, Audra Devoto, Jennifer Oki, Ashcon Khoubyari, Daniela S. Aliaga Goltsman, Jyun-Liang Lin, Cristina N. Butterfield, Christopher T. Brown, Brian C. Thomas, Gregory J. Cost
Publikováno v:
The CRISPR Journal.
Autor:
Matthew R. Olm, Cristina N. Butterfield, Alex Copeland, T. Christian Boles, Brian C. Thomas, Jillian F. Banfield
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT In this study, strain-resolved metagenomics was used to solve a mystery. A 6.4-Mbp complete closed genome was recovered from a soil metagenome and found to be astonishingly similar to that of Delftia acidovorans SPH-1, which was isolated in
Externí odkaz:
https://doaj.org/article/131b6608c9964b34aaf3fa17cf8896f5
Akademický článek
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Autor:
Brian C. Thomas, Christopher T. Brown, Audra E. Devoto, Lisa Alexander, Daniela S. Aliaga Goltsman, Cristina N. Butterfield, Justine B. Albers, Jason Liu
Publikováno v:
The CRISPR Journal
Cas12a enzymes are quickly being adopted for use in a variety of genome-editing applications. These programmable nucleases are part of adaptive microbial immune systems, the natural diversity of which has been largely unexplored. Here, we identified
Autor:
Cristina N. Butterfield, Zhou Li, Peter F. Andeer, Susan Spaulding, Brian C. Thomas, Andrea Singh, Robert L. Hettich, Kenwyn B. Suttle, Alexander J. Probst, Susannah G. Tringe, Trent Northen, Chongle Pan, Jillian F. Banfield
Publikováno v:
PeerJ, Vol 4, p e2687 (2016)
Annually, half of all plant-derived carbon is added to soil where it is microbially respired to CO2. However, understanding of the microbiology of this process is limited because most culture-independent methods cannot link metabolic processes to the
Externí odkaz:
https://doaj.org/article/53e34cf41ce2444096f56351db78bc59
Autor:
Spencer Diamond, Cristina N. Butterfield, Alexander Crits-Christoph, Brian C. Thomas, Jillian F. Banfield
Publikováno v:
Nature, vol 558, iss 7710
Crits-Christoph, A; Diamond, S; Butterfield, CN; Thomas, BC; & Banfield, JF. (2018). Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis. Nature, 558(7710), 440-444. doi: 10.1038/s41586-018-0207-y. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/86p2r24g
Crits-Christoph, A; Diamond, S; Butterfield, CN; Thomas, BC; & Banfield, JF. (2018). Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis. Nature, 558(7710), 440-444. doi: 10.1038/s41586-018-0207-y. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/86p2r24g
© 2018 Macmillan Publishers Ltd., part of Springer Nature. In soil ecosystems, microorganisms produce diverse secondary metabolites such as antibiotics, antifungals and siderophores that mediate communication, competition and interactions with other
Akademický článek
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Autor:
Cristina N. Butterfield, Meghan D. Storlie, Diego A. Espinosa, Brian C. Thomas, Gregory J. Cost, Andres Rivas, Rebecca C. Lamothe, Lisa Alexander, Daniela S. Aliaga Goltsman, Christopher T. Brown
Publikováno v:
Blood. 138:3984-3984
Gene-editing technology has revolutionized molecular therapeutics, enabling DNA-engineering-based approaches to treat disease. Despite this, development of medicines using gene editing has been hampered by technological, immunological, and legal limi