Zobrazeno 1 - 10
of 32
pro vyhledávání: '"N. Bostijn"'
Publikováno v:
European Journal of Pharmaceutical Sciences. 132:106-117
Recently, an innovative continuous manufacturing technology for a pharmaceutical oral suspension was proposed, based on two consecutive mixing units. A limitation of this technology is the need to dissolve or disperse powder-based raw materials in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe23a5ac768c8afbe72841e4ba0ecb8
https://doi.org/10.1016/j.ejps.2019.02.036
https://doi.org/10.1016/j.ejps.2019.02.036
Publikováno v:
European Journal of Pharmaceutical Sciences. 123:576-583
The aim of this study was to investigate the applicability of an innovative continuous manufacturing system for semi-solid and liquid pharmaceutical formulations. A commercially available pharmaceutical oral suspension was selected as model formulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef84a50f47f34b91f23c3dd6d80cc97a
https://doi.org/10.1016/j.ejps.2018.08.015
https://doi.org/10.1016/j.ejps.2018.08.015
Autor:
Valérie Vanhoorne, Jens Dhondt, Edina Szabó, N. Bostijn, T. De Beer, Alexander Ryckaert, W. Dhondt, Chris Vervaet, B. Van Snick
Publikováno v:
INTERNATIONAL JOURNAL OF PHARMACEUTICS
In this study, the volumetric and gravimetric feeding behavior of 15 pharmaceutical powders on a low feed rate feeder was correlated with their material properties through a multivariate approach. The powders under investigation differ substantially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7aa8dbfc98beef105f59b445482d55
https://biblio.ugent.be/publication/8610747
https://biblio.ugent.be/publication/8610747
Autor:
Jurgen Vercruysse, J.P. Remon, Chris Vervaet, Ingmar Nopens, Y. Vander Heyden, T. De Beer, N. Bostijn, F. De Leersnyder, Valérie Vanhoorne, P. Cappuyns, Michael Ghijs, Maxim Verstraeten, I. Van Assche, Eric Ziemons, H. Bekaert
Although twin screw granulation has already been widely studied in recent years, only few studies addressed the subsequent continuous drying which is required after wet granulation and still suffers from a lack of detailed understanding. The latter i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb0822b74b755af8ab5bec43f65a002
https://biblio.vub.ac.be/vubir/breakage-and-drying-behaviour-of-granules-in-a-continuous-fluid-bed-dryer-influence-of-process-parameters-and-wet-granule-transfer(dc984a9c-aba6-4be0-9765-b2625559cd7e).html
https://biblio.vub.ac.be/vubir/breakage-and-drying-behaviour-of-granules-in-a-continuous-fluid-bed-dryer-influence-of-process-parameters-and-wet-granule-transfer(dc984a9c-aba6-4be0-9765-b2625559cd7e).html
Publikováno v:
ANALYTICA CHIMICA ACTA
UltraViolet (UV) spectroscopy was evaluated as an innovative Process Analytical Technology (PAT) - tool for the in-line and real-time quantitative determination of low-dosed active pharmaceutical ingredients (APIs) in a semi-solid (gel) and a liquid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7082cace9f5c65a36d383bad47319a05
https://hdl.handle.net/1854/LU-8556792
https://hdl.handle.net/1854/LU-8556792
Autor:
J.P. Remon, Jurgen Vercruysse, Mafalda C. Sarraguça, João A. Lopes, Ana Filipa Silva, N. Bostijn, F. De Leersnyder, Chris Vervaet, T. De Beer, Maxim Verstraeten, Margot Fonteyne, Valérie Vanhoorne
Publikováno v:
International journal of pharmaceutics. 528(1-2)
A multivariate statistical process control (MSPC) strategy was developed for the monitoring of the ConsiGma™-25 continuous tablet manufacturing line. Thirty-five logged variables encompassing three major units, being a twin screw high shear granula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f4d9e90cc41d1464eec265902e0830
https://pubmed.ncbi.nlm.nih.gov/28583334
https://pubmed.ncbi.nlm.nih.gov/28583334
Autor:
Pieter Rombouts, Valérie Vanhoorne, N. Bostijn, Chris Vervaet, T. De Beer, J.P. Remon, Lutz Nuhn, G. Verstraete, W. Grymonpré, S.Van Herck
Publikováno v:
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Since the concept of continuous processing is gaining momentum in pharmaceutical manufacturing, a thorough understanding on how process and formulation parameters can impact the critical quality attributes (CQA) of the end product is more than ever r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc3dac35cd15b0e261e305d70c9f523
https://biblio.ugent.be/publication/8550662
https://biblio.ugent.be/publication/8550662
PAT-based batch statistical process control of a manufacturing process for a pharmaceutical ointment
Publikováno v:
European Journal of Pharmaceutical Sciences. 136:104946
In this study, a process analytical technology (PAT)-based batch statistical process control (BSPC) model was developed for the laboratory-scale manufacturing process of a commercially available pharmaceutical ointment. The multivariate BSPC model wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705765843b61270e176c5ca5eaf4dbab
https://doi.org/10.1016/j.ejps.2019.05.024
https://doi.org/10.1016/j.ejps.2019.05.024
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Akademický článek
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