Zobrazeno 1 - 10
of 309
pro vyhledávání: '"N. Agar"'
Autor:
Md Amin Hossain, Richa Sarin, Daniel P Donnelly, Brandon C Miller, Alexandra Weiss, Luke McAlary, Svetlana V Antonyuk, Joseph P Salisbury, Jakal Amin, Jeremy B Conway, Samantha S Watson, Jenifer N Winters, Yu Xu, Novera Alam, Rutali R Brahme, Haneyeh Shahbazian, Durgalakshmi Sivasankar, Swathi Padmakumar, Aziza Sattarova, Aparna C Ponmudiyan, Tanvi Gawde, David E Verrill, Wensheng Yang, Sunanda Kannapadi, Leigh D Plant, Jared R Auclair, Lee Makowski, Gregory A Petsko, Dagmar Ringe, Nathalie Y R Agar, David J Greenblatt, Mary Jo Ondrechen, Yunqiu Chen, Justin J Yerbury, Roman Manetsch, S Samar Hasnain, Robert H Brown, Jeffrey N Agar
Publikováno v:
PLoS Biology, Vol 22, Iss 1, p e3002462 (2024)
Mutations in the gene encoding Cu-Zn superoxide dismutase 1 (SOD1) cause a subset of familial amyotrophic lateral sclerosis (fALS) cases. A shared effect of these mutations is that SOD1, which is normally a stable dimer, dissociates into toxic monome
Externí odkaz:
https://doaj.org/article/ae0b075acaa84b09a950667731983ac1
Autor:
Anya B. Zhong, Isabella H. Muti, Stephen J. Eyles, Richard W. Vachet, Kristen N. Sikora, Cedric E. Bobst, David Calligaris, Sylwia A. Stopka, Jeffery N. Agar, Chin-Lee Wu, Mari A. Mino-Kenudson, Nathalie Y. R. Agar, David C. Christiani, Igor A. Kaltashov, Leo L. Cheng
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The status of metabolomics as a scientific branch has evolved from proof-of-concept to applications in science, particularly in medical research. To comprehensively evaluate disease metabolomics, multiplatform approaches of NMR combining with mass sp
Externí odkaz:
https://doaj.org/article/5cfbe20407d341d4a29f4d0281cf00e6
Autor:
Nathalie Y.R. Agar, Fiona M. Fennessy, Clare M. Tempany, Massimo Loda, Jeffrey N. Agar, Sankha S. Basu, Sudeepa Syamala, Begona G.C. Lopez, Paolo Chetta, Giorgia Zadra, Elizabeth C. Randall
S1. Segmentation map of a subset of lower Gleason tissue specimens, demonstrates regional differences between tumor and normal tissue, and between the two different Gleason grades S2. Example MALDI ion images of 2 long chain acylcarnitine species S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c624948c3a7fb3b5d8b559f9a9ee0b
https://doi.org/10.1158/1541-7786.22512570.v1
https://doi.org/10.1158/1541-7786.22512570.v1
Autor:
Nathalie Y.R. Agar, Fiona M. Fennessy, Clare M. Tempany, Massimo Loda, Jeffrey N. Agar, Sankha S. Basu, Sudeepa Syamala, Begona G.C. Lopez, Paolo Chetta, Giorgia Zadra, Elizabeth C. Randall
Diagnosis of prostate cancer is based on histologic evaluation of tumor architecture using a system known as the “Gleason score.” This diagnostic paradigm, while the standard of care, is time-consuming, shows intraobserver variability, and provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62f2ea0bf35c3250bec50cbf954ecc9c
https://doi.org/10.1158/1541-7786.c.6540276.v1
https://doi.org/10.1158/1541-7786.c.6540276.v1
Akademický článek
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Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Heatmap of mRNA sequencing data, highlighting the activated genes within pathways for glycolysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec4ac3c1a25630a9b6272798dfc6aec
https://doi.org/10.1158/0008-5472.22424722.v1
https://doi.org/10.1158/0008-5472.22424722.v1
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Glioblastoma (GBM) is increasingly recognized as a disease involving dysfunctional cellular metabolism. GBMs are known to be complex heterogeneous systems containing multiple distinct cell populations and are supported by an aberrant network of blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8cc9e0b4bcc12f4c9a655a7f9d4396
https://doi.org/10.1158/0008-5472.c.6511855.v1
https://doi.org/10.1158/0008-5472.c.6511855.v1
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Heatmap of mRNA sequencing data, highlighting the activated genes within pathways for fatty acid metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50814cd38c71005c9cbcca89250a65b2
https://doi.org/10.1158/0008-5472.22424725.v1
https://doi.org/10.1158/0008-5472.22424725.v1
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Annotated peaklists from MALDI FT ICR MSI data, including measured m/z, possible identification according to Lipid Maps database and associated Δppm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29eaee5645a82589104e91d2e93d5b7a
https://doi.org/10.1158/0008-5472.22424731
https://doi.org/10.1158/0008-5472.22424731
Autor:
Nathalie Y.R. Agar, Jann N. Sarkaria, Forest M. White, William F. Elmquist, Nhan L. Tran, Jeffrey N. Agar, Marcia C. Haigis, Haejin Yoon, Sandro Santagata, Sankha S. Basu, Walid M. Abdelmoula, Michael S. Regan, Sen Peng, Begoña G.C. Lopez, Elizabeth C. Randall
Supplementary results, Supplementary figures S1-S9 and Supplementary methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c8dfc9f31bd9dc8febc4a48c77e0b4
https://doi.org/10.1158/0008-5472.22424716
https://doi.org/10.1158/0008-5472.22424716