Zobrazeno 1 - 10
of 486
pro vyhledávání: '"N. AMICO"'
Autor:
Rebecca N. D’Amico, Yuliana K. Bosken, Kathleen F. O’Rourke, Alec M. Murray, Woudasie Admasu, Chia-en A. Chang, David D. Boehr
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Networks of noncovalent amino acid interactions propagate allosteric signals throughout proteins. Tryptophan synthase (TS) is an allosterically controlled bienzyme in which the indole product of the alpha subunit (αTS) is transferred through a 25 Å
Externí odkaz:
https://doaj.org/article/2ebbcdaede4741bf8dc39da2cd8100d3
Publikováno v:
Alcohol: Clinical and Experimental Research. 47:240-250
A major DSM-5 criterion for Alcohol Use Disorder is the continuation of alcohol consumption despite negative consequences. This has been modeled in mice using adulteration of alcohol solution with the bitter tastant quinine. Mice that continue to con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3199e7e549ce259e4472d4fd5840298
https://doi.org/10.1111/acer.15006
https://doi.org/10.1111/acer.15006
Publikováno v:
Psychopharmacology. 239:3277-3286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62fd5fb98238e5df5b14940b361a889e
https://doi.org/10.1007/s00213-022-06210-9
https://doi.org/10.1007/s00213-022-06210-9
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
Tryptophan synthase is a model system for understanding allosteric regulation within enzyme complexes. Amino acid interaction networks were previously delineated in the isolated alpha subunit (αTS) in the absence of the beta subunit (βTS). The amin
Externí odkaz:
https://doaj.org/article/deff1c5a046849e2b53ae9e25ec4a88e
Autor:
Dhiren Kataria, Andrea Santangelo, Monica Colpi, Enrico Costa, Carlo Rovelli, Alessandro Papitto, Salvatore Capozziello, N. D'Amico, Alessandro Riggio, Kevin Hurley, Marco Feroci, M. Branchesi, M. Della Valle, Giuseppe Lodato, F. Frontera, Angelo Gambino, Tsvi Piran, P. de Bernardis, T. Di Salvo, Lorenzo Amati, E. Coccia, Gabriele Ghisellini, Silvia Zane, Heino Falcke, Barbara Negri, Giovanni Amelino-Camelia, M. De Laurentis, Claudio Labanti, F. Vidotto, Fabrizio Fiore, Andrea Sanna, R. Iaria, Luciano Burderi
GrailQuest(Gamma Ray Astronomy International Laboratory for QUantum Exploration of Space-Time) is a mission concept based on a constellation (hundreds/thousands) of nano/micro/small-satellites in low (or near) Earth orbits. Each satellite hosts a non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015ed845cada21a22eee80481878f268
http://hdl.handle.net/20.500.12386/31874
http://hdl.handle.net/20.500.12386/31874
Publikováno v:
Protein Sci
Experimental observations of enzymes under active turnover conditions have brought new insight into the role of protein motions and allosteric networks in catalysis. Many of these studies characterize enzymes under dynamic chemical equilibrium condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1daaad00121e67b6dcb96fcde44286c
https://pubmed.ncbi.nlm.nih.gov/33314435
https://pubmed.ncbi.nlm.nih.gov/33314435
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 42(9)
A general framework by which dynamic interactions within a protein will promote the necessary series of structural changes, or "conformational cycle," required for function is proposed. It is suggested that the free-energy landscape of a protein is b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c39c18f2b758c0468aa3fe38ad015f
https://pubmed.ncbi.nlm.nih.gov/32720327
https://pubmed.ncbi.nlm.nih.gov/32720327
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
The endemic Pyrenean Desman (Galemys pyrenaicus) is an elusive, rare, and vulnerable species declining over its entire and narrow range (Spain, Portugal, France, and Andorra). The principal set of conservation measures in France is a 5-years National
Externí odkaz:
https://doaj.org/article/00045ac2dd754103900be1c214fca8c4
Publikováno v:
Protein Science. 27:825-838
Enzymes undergo a range of internal motions from local, active site fluctuations to large-scale, global conformational changes. These motions are often important for enzyme function, including in ligand binding and dissociation and even preparing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6218acb319c9b12e6c05e22eeabdeb5a
https://doi.org/10.1002/pro.3379
https://doi.org/10.1002/pro.3379
Autor:
Christine Jordan, Michael Kramer, Pablo Torne, Paulo C. C. Freire, Alessandro Ridolfi, Craig O. Heinke, Andrew Lyne, Duncan R. Lorimer, N. D'Amico, R. N. Manchester, Fernando Camilo, John Sarkissian
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 471:857-876
This paper is the second in a series where we report the results of the long-term timing of the millisecond pulsars (MSPs) in 47 Tucanae with the Parkes 64-m radio telescope. We obtain improved timing parameters that provide additional information fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6151e2403e3afe4335a4d517562f0016
https://doi.org/10.1093/mnras/stx1533
https://doi.org/10.1093/mnras/stx1533