Zobrazeno 1 - 10
of 42
pro vyhledávání: '"N. A. Simonian"'
Autor:
N. V. Zabolotskikh, E. Y. Vyrodova, A. O. Dorosheva, M. A. Semerdzhian, N. E. Simonian, M. V. Shamaeva, A. R. Artyushkova
Publikováno v:
Кубанский научный медицинский вестник, Vol 27, Iss 6, Pp 109-122 (2020)
Background. Mental and physical health of students is directly linked to the emotional safety of educational environment and its recent transformation. Adoption of distance learning and IT innovations in educational practice influences students’ p
Externí odkaz:
https://doaj.org/article/4876ae280f2a4584aae12efebaacc95f
Autor:
Monika Baier, Elizabeth Fisher, N. A. Simonian, Bianca Weinstock-Guttman, Deborah M. Miller, Richard A. Rudick, Michele Mass, Gary Cutter, David S Doughtery
Publikováno v:
Multiple Sclerosis Journal. 9:1-5
Health-Related Q uality of Life (HRQ oL) research is gaining acceptance in the field of multiple sclerosis (MS). Little is known about what precipitates quality of life change. It was hypothesized that physical aspects of quality of life decline with
Autor:
Elizabeth Fisher, Richard A. Rudick, D. S. Dougherty, Monika Baier, Michele Mass, N. A. Simonian, Jar-Chi Lee, Jack H. Simon, Bianca Weinstock-Guttman, Gary Cutter, David Miller
Publikováno v:
Neurology. 59:1412-1420
Objective: To characterize whole-brain atrophy in relapsing-remitting MS (RRMS) patients over an 8-year period. The specific goals of this study were to determine if brain atrophy is related to subsequent disability status and to identify MRI correla
Autor:
N. A. Simonian, Elizabeth M. C. Fisher, Richard A. Rudick, Michele Mass, Monika Baier, Bianca Weinstock-Guttman, Darin D. Dougherty, DH Miller, Gary Cutter
Publikováno v:
Neurology. 56:1324-1330
Objective: To determine whether the MS Functional Composite (MSFC) can predict future disease progression in patients with relapsing remitting MS (RR-MS). Background: The MSFC was recommended by the Clinical Outcomes Assessment Task Force of the Nati
Autor:
N. A. Simonian, J H Simon, Roy W. Beck, T J Murray, Lawrence Jacobs, Alfred Sandrock, P J Slasor, C. M. Brownscheidle, R. P. Kinkel
Publikováno v:
New England Journal of Medicine. 343:898-904
Background Treatment with interferon beta has been shown to help patients with established multiple sclerosis, but it is not known whether initiating treatment at the time of a first clinical demyelinating event is of value. Methods We conducted a ra
Autor:
N. A. Simonian, Bianca Weinstock-Guttman, John R. Richert, Wendy Jones, Michael E. Coats, Robert M. Herndon, Michele Mass, Richard A. Rudick, Donald E. Goodkin, BK Burnett, James Scaramucci, Emmanuelle Waubant, Lawrence Jacobs
Publikováno v:
International Journal of MS Care. 1:3-11
In a phase III, double-blind, placebo-controlled, 2-year clinical trial, interferon beta-1a (IFN-β-1a, Avonex) treatment significantly delayed disability progression, decreased exacerbations, and reduced brain lesions on magnetic resonance imaging (
Autor:
N. A. Simonian, Kathy O'Reilly, J. S. Fischer, Michele K. Mass, Jonathan Braiman, Lawrence Jacobs, K. E. Wende, Frederick E. Munchsauer, Barbara J. Scherokman, Carol M. Brownscheidle, Carl V. Granger, Robert M. Herndon, David S. Dougherty, David M. Bartoszak, Donald E. Goodkin, John R. Richert, Bianca Weinstock-Guttman, Richard A. Rudick, Roger L. Priore, Andres M. Salazar, Diane Cookfair, Stanley L. Cohan, Ruth H. Whitham, Dennis Bourdette, Michael E. Coats, R. P. Kinkel, Richard M. Ransohoff, Patrick M. Pullicino, Jack H. Simon
Publikováno v:
Journal of Neuroimmunology. 93:8-14
Background and objective : This report provides results of CSF analyses done in a subset of relapsing remitting MS patients participating in a placebo-controlled, double-blind, phase III clinical trial of IFNβ-Studies supported by the National Multi
Autor:
N. A. Simonian, Andres M. Salazar, Wendy Jones, M. Campion, Bianca Weinstock-Guttman, Michele Mass, J. A. Alam, James Scaramucci, Richard A. Rudick, Donald E. Goodkin, Lawrence Jacobs, John R. Richert, Frederick Munschauer, Diane Cookfair, Robert M. Herndon, Michael E. Coats, Jack H. Simon
Publikováno v:
Neurology. 50:1266-1272
Background: Interferon beta is an effective treatment for relapsing multiple sclerosis(MS). As with other protein drugs, neutralizing antibodies (NAB) can develop that reduce the effectiveness of treatment. Objectives: To determine the incidence and
Autor:
Ann Scherzinger, Bianca Weinstock-Guttman, Frederick Munschauer, Carol M. Brownscheidle, Carl V. Granger, Roger L. Priore, Richard A. Rudick, John J. Alam, Patrick M. Pullicino, Lawrence Jacobs, Jack H. Simon, Robert M. Herndon, Michele Mass, Andres M. Salazar, Jeanelle Sheeder, K. E. Wende, N. A. Simonian, Stanley Cohan, Michelle Lajaunie, David S. Dougherty, Jonathan Braiman, Diane Cookfair, J. S. Fischer, Ruth H. Whitham, Michael E. Coats, Mary Joel Meyer, Donald E. Goodkin, David M. Bartoszak, Kim Choi, Dennis Bourdette, Barbara J. Scherokman, John R. Richert, R. P. Kinkel, Anna L. Martens-Davidson, M. Campion
Publikováno v:
Annals of Neurology. 43:79-87
The Multiple Sclerosis Collaborative Research Group trial was a double-blind, randomized, multicenter, phase III, placebo-controlled study of interferon beta-1a (IFNbeta-1a; AVONEX) in relapsing forms of multiple sclerosis. Initial magnetic resonance
Autor:
R. H. Whitham, D. S. Dougherty, P. M. Pullicino, David M. Bartoszak, Michael E. Coats, J. S. Fischer, Jack H. Simon, C. M. Brownscheidle, L. D. Jacobs, Richard A. Rudick, B. Weistock-Guttman, N. A. Simonian, B. J. Scherokman, J. R. Richert, C. V. Granger, Robert M. Herndon, Michele Mass, D. L. Cookfair, Andres M. Salazar, R. L. Priore, J. J. Alam, R. P. Kinkel, Dennis Bourdette, F. E. Munschauer, Jonathan Braiman, S. L. Cohan, Donald E. Goodkin, M. K. Campion
Publikováno v:
Neurology. 49:358-363
Background and Objective: A phase III double-blind, placebo-controlled clinical trial demonstrated that interferon beta-la (IFNβ-1a) (Avonex, Biogen) significantly delayed progression of disability in relapsing MS patients. The primary clinical outc