Zobrazeno 1 - 10
of 82
pro vyhledávání: '"N. A. Oborotova"'
Autor:
T. A. Timofeeva, M. V. Dmitrieva, L. L. Nikolaeva, O. L. Orlova, N. A. Oborotova, A. P. Polozkova, I. I. Krasnyuk
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 8, Iss 2, Pp 66-73 (2019)
Introduction. Liposomal technologies are widely used in medicine and cosmetology as a delivery system for diagnostic and medicinal products and biologically active substances. The undoubted practical importance at the stage of development of a liposo
Externí odkaz:
https://doaj.org/article/6e03f90b753142b6bffe3b032b4ea752
Autor:
I. D. Gulyakin, L. L. Nikolaeva, M. V. Dmitrieva, N. A. Oborotova, E. V. Ignatieva, N. A. Dmitricheva, I. V. Yartseva, Z. S. Shprakh
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 4, Pp 118-122 (2019)
In order to ensure reliable and accurate results, the authors carried out the validation procedure developed technique for spectrophotometric quantification of the active substance for the lyophilized liposomal formulation of national hydrophobic ant
Externí odkaz:
https://doaj.org/article/5fb6cc02d6134201a32942286d819812
Autor:
I. D. Gulyakin, L. L. Nikolaeva, M. V. Dmitrieva, O. L. Orlova, A. P. Polozkova, N. A. Oborotova, E. V. Ignatieva, N. A. Dmitricheva, I. V. Yartseva, Z. S. Shprakh
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 4, Pp 62-67 (2019)
The work is dedicated to the development of technology for obtaining a freeze-dried dosage form LHS-1208 and the establishment of methods of quality control of the drug. The authors have shown spectrophotometric analysis techniques and flash chromato
Externí odkaz:
https://doaj.org/article/c758b46251224c65b6a7a11af9cbe183
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 3, Pp 36-44 (2019)
The main objective of pharmaceutical technology is to maximize the use of «pharmaceutical factors» for ensuring the high quality of prepared medicines, which coincides with the strategic task of biopharmacy, which is to maximize the effectiveness o
Externí odkaz:
https://doaj.org/article/e5dfd30265364eb08e71c10cac930a79
Autor:
I. D. Gulyakin, L. L. Nikolaeva, N. A. Oborotova, M. V. Dmitrieva, A. V. Lantsova, E. V. Sanarova, O. L. Orlova, A. P. Polozkova, H. I. Lavrukhin, N. D. Bunyatyan
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 2, Pp 52-59 (2019)
There are several methods for solving the problem of an adequate dosage form for the hydrophobic and poorly soluble pharmaceutical substances which comprise a structure modification, preparation of solid dispersion systems, a change in pH, the use of
Externí odkaz:
https://doaj.org/article/f62bee0a608c4073866dcc9221c24606
Autor:
O. L. Orlova, L. L. Nikolaeva, L. A. Korol, M. V. Dmitrieva, A. P. Polozkova, A. V. Lantsova, I. D. Gulyakin, N. A. Oborotova
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 6, Iss 5, Pp 440-461 (2018)
Despite the development of biotherapy, chemotherapy remains one of the main methods of treatment of cancer patients. Currently, there are more than 100 anticancer drug substances, however, every year new drugs enter clinical practice and various ther
Externí odkaz:
https://doaj.org/article/d265b4e270f3454ea2dde2130974f77b
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 4, Iss 2(15), Pp 88-94 (2016)
This article deals with the selection of the mobile and stationary phase for identifying polyvinylpyrrolidone formulations drug compounds by TLC.
Externí odkaz:
https://doaj.org/article/4ba447b249e24fd5b970a584e632f025
Publikováno v:
Pharmaceutical Chemistry Journal. 56:974-978
Autor:
O. L. Orlova O. L. Orlova, L. L. Nikolaeva, A. P. Polozkova, M. V. Dmitrieva, N. A. Oborotova, I. D. Gulyakin
Publikováno v:
Farmacevticheskoe delo i tehnologija lekarstv (Pharmacy and Pharmaceutical Technology). :66-78
Aim. The aim of this work was to create a lyophilized liposomal dosage form of native hydrophobic antitumor compound from the group of indolocarbazole derivatives — LHS-1208. Materials and methods. Quantitative determination of the drug content was
Autor:
Ekaterina Sanarova, L. L. Nikolaeva, O. L. Orlova, N. A. Oborotova, Maria Dmitrieva, Anna Lantsova, N. D. Bunyatyan, Galina Glembotskaya
Publikováno v:
International Journal of Applied Pharmaceutics. :241-244
Objective: This study was undertaken with the aim of the validate the simple isocratic metods high-performance liquid chromatographic (HPLC) for the estimation of PEG-2000-DSPE and sucrose in liposomal medicinal formulations of the phthalocyanine pho