Zobrazeno 1 - 2
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pro vyhledávání: '"N. A. McCarty"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Sphingomyelinase C (SMase) inhibits CFTR chloride channel activity in multiple cell systems, an effect that could exacerbate disease in CF and COPD patients. The mechanism by which sphingomyelin catalysis inhibits CFTR is not known but evide
Externí odkaz:
https://doaj.org/article/ba396a046c6144c2814476c6c4bace4e
Autor:
Y, Uezono, J, Bradley, C, Min, N A, McCarty, M, Quick, J R, Riordan, C, Chavkin, K, Zinn, H A, Lester, N, Davidson
Publikováno v:
Receptorschannels. 1(3)
The cystic fibrosis transmembrane conductance regulator (CFTR), a Cl- channel activated by phosphorylation, was expressed in Xenopus oocytes along with various combinations of several other components of the cAMP signalling pathway. Activation of the