Zobrazeno 1 - 8
of 8
pro vyhledávání: '"N. A. Kikhtenko"'
Autor:
N. A. Kikhtenko, N. A. Bondarenko, N. P. Bgatova, L. A. Oleynik, O. V. Poveshchenko, A. Zh. Fursova, P. G. Madonov
Publikováno v:
Безопасность и риск фармакотерапии, Vol 9, Iss 4, Pp 200-208 (2021)
Currently, there are no efficacious, all-purpose antiviral medicines for the treatment of ocular surface infections caused by viruses. At the same time, type III interferons demonstrate high potency for histological barriers, such as the conjunctiva.
Externí odkaz:
https://doaj.org/article/95492679dd1240b2ad09b411ed82eced
Publikováno v:
Сибирский научный медицинский журнал, Vol 41, Iss 5, Pp 31-36 (2021)
The aim of the study was to determine the efficacy of recombinant human interferon lambda 1 (IFN-λ1) against human adenovirus serotype 5 in a culture of human conjunctival cells Chang conjunctiva clone 1-5c-4. Material and methods. The study design
Externí odkaz:
https://doaj.org/article/8abf90bff5b045259a083149d80b72f5
Publikováno v:
Сибирский научный медицинский журнал, Vol 40, Iss 2, Pp 15-23 (2020)
Interferons are a group of protein molecules with a broad spectrum of effects on the human body. Interferon lambda (type III interferon) was discovered comparatively recently about 20 years ago and its action is still poorly understood. However, the
Externí odkaz:
https://doaj.org/article/5bc929943b2d486eb7192c879812c0a1
Autor:
N. A. Kikhtenko, P. G. Madonov
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 3, Pp 117-125 (2019)
The review contains an analysis of the medical use of interferons – a group of signaling protein molecules that have antiviral, antitumor, and immunomodulatory activity – in ophthalmic practice. Interferons have a wide spectrum of action, includi
Externí odkaz:
https://doaj.org/article/7086727b78484912a262437157f5556c
Autor:
L. A. Oleinik, V. A. Svyatchenko, Pavel Madonov, A. A. Kotlyarova, German Baikalov, S. S. Legostaev, N. A. Kikhtenko
Publikováno v:
Bulletin of Experimental Biology and Medicine
The antiviral activity of recombinant human IFN-lambda type 1 (IFNλ-1) against culture strain of SARS-CoV-2 virus was determined by infecting a highly sensitive VeroE6 coronavirus cell culture after preincubation test (the cell monolayer was incubat
Autor:
V. A. Svyatchenko, Pavel Madonov, A. A. Kotlyarova, L. A. Oleinik, V. V. Udut, German Baikalov, S. S. Legostaev, N. A. Kikhtenko
Publikováno v:
Экспериментальная и клиническая фармакология. 84:15-20
Несмотря на значительные достижения в создании лекарственных средств, на сегодняшний день не существует эффективных универсальных пре
Publikováno v:
Bulletin of experimental biology and medicine. 173(2)
We studied the pharmacokinetics of a pegylated IFN-λ1 (PEG IFN-λ1) after its oral administration to rats in different therapeutic doses. The hypothesis on linear pharmacokinetics of PEG IFN-λ1 within the dose range of 2.6-7.8 μg/kg was confirmed,
Autor:
A. M. Shestopalov, N. V. Kikhtenko, A. N. Sergeev, V. N. Mikheev, T. N. Il’Icheva, A. B. Ryzhikov
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 1, Pp 44-50 (2013)
Avian flu is an infectious viral disease in birds that still retains its positions in some parts of Asia and Africa. This review contains summarization and analysis of facts regarding the current situation on highly pathogenic avian flu A-type subtyp