Zobrazeno 1 - 10
of 14
pro vyhledávání: '"N. A. Gomzina"'
Autor:
N. B. Viktorov, Andrey G Alexandrov, O. F. Kuznetsova, Daria D Vaulina, Mariia M Kiseleva, Nikolay N Kuzmich, Konstantin V. Sivak, N. A. Gomzina
Publikováno v:
ChemistrySelect. 5:2685-2689
Autor:
Nikolay N Kuzmich, Konstantin V. Sivak, N. A. Gomzina, O. F. Kuznetsova, Andrey G Aleksandrov, Kira I. Stosman, Nikolai B Viktorov, Mariia M Kiseleva, Daria D Vaulina
Publikováno v:
Molecules
Molecules, Vol 26, Iss 6630, p 6630 (2021)
Volume 26
Issue 21
Molecules, Vol 26, Iss 6630, p 6630 (2021)
Volume 26
Issue 21
Neolignans honokiol and 4′-O-methylhonokiol (MH) and their derivatives have pronounced anti-inflammatory activity, as evidenced by numerous pharmacological studies. Literature data suggested that cyclooxygenase type 2 (COX-2) may be a target for th
Autor:
N. B. Viktorov, A. A. Muzhikyan, Daria D Vaulina, N. A. Gomzina, K. V. Sivak, K. I. Stosman, A. G. Alexandrov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:425-429
The synthesis of two derivatives of lignan 4'-O-methylhonokiol (MH), i.e., 4'-methoxy-5-propyl-1,1'-biphenyl-2-ol (III) and 4'-(2-fluoroethoxy)-2-hydroxy-5-propyl-1,1'-biphenyl (VI) has been described. Derivative (VI) demonstrates the highest anti-in
Publikováno v:
Applied Radiation and Isotopes. 135:110-114
This paper describes the novel approach for preparation of [18F]flumazenil ([18F]FMZ), well known radioligand for assessment of GABAA receptors by PET. The optimized reaction conditions allowed us to implement commercially available SPE cartridges fo
Publikováno v:
Russian Chemical Bulletin. 65:794-800
An express method of solid-phase extraction was proposed for the first time for isolation and purification of [18F]flumazenil, a radioligand used to quantify the density of central benzodiazepine receptors by positron emission tomography (PET). This
Publikováno v:
Russian Chemical Bulletin. 64:1536-1546
The main methods for the production of of 11С-methylating agents and traditional and new perspective routes for their use in the synthesis of radiopharmaceuticals for positron emission tomography were considered.
Publikováno v:
Russian Chemical Bulletin. 63:1164-1168
A labeled tyrosine analog, viz., l-[O-11C-methyl]tyrosine ([11C]MT), was obtained by a reaction of [11C]-methyl iodide with a tyrosine salt in DMSO in the presence of tetrabutylammonium hydroxide on the Sep-Pak tC18 cartridge surface. The efficiency
Autor:
N. A. Gomzina, O. F. Kuznetsova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 37:191-197
L-[methyl-(11C)]-methionine ([11C]MET), labelled with carbon-11 (T1/2 = 20 min), is the most commonly used amino acid radiotracer for PET diagnostics of brain tumors. The production of [11C]MET via on-line 11C-methylation of L-homocysteine thiolacton
Publikováno v:
Radiochemistry. 49:299-304
The possibility of using 2-[18F]fluoroethyl bromide ([18F]FEB) as labeled reagent for selective O-[18F]fluoroethylation of phenolic group in the presence of an unprotected amino group in an amino acid molecule was demonstrated by the example of the s
Autor:
Nicholas Seneca, Raisa Krasikova, N. A. Gomzina, Nikolaj N. Ryzhikov, Ivanka Savic, Christer Halldin, Evgeny Shchukin, Balázs Gulyás, Håkan Hall, Dmitrij A. Vassiliev, Olga S. Fedorova
Publikováno v:
Nuclear Medicine and Biology. 32:109-116
A straightforward method for the preparation of no-carrier-added (n.c.a.) [18F]flumazenil via standard nucleophilic radiofluorination of the corresponding nitro-analog Ro 15-2344 has been developed. The labeling was performed by employing the K18F/kr