Zobrazeno 1 - 10
of 29
pro vyhledávání: '"N. A. Flavahan"'
Publikováno v:
British journal of pharmacology. 158(5)
In mouse tail arteries, selective alpha(2)-adrenoceptor antagonism with rauwolscine caused powerful dilation during constriction to the alpha(1)-adrenoceptor agonist phenylephrine. This study therefore assessed phenylephrine's selectivity at vascular
Autor:
N I, Moldovan, Z, Qian, Y, Chen, C, Dong, A, Ying, R H, Hruban, N A, Flavahan, W M, Baldwin III, F, Sanfilippo, P J, Goldschmidt-Clermont
Publikováno v:
Angiogenesis. 2(3)
Pathological conditions have been recognized where vessel destruction is a prominent feature of the pathogenic process. One such condition consists of the chronic rejection of blood vessels in transplanted solid organs. Accelerated graft arterioscler
Publikováno v:
Arthritis and rheumatism. 43(8)
Vasospasm and ischemic organ injury are important in the pathogenesis of systemic sclerosis (SSc; scleroderma). The present study was performed to determine whether SSc arterioles have an intrinsic disturbance in vasoconstrictor activity.Skin biopsy
Publikováno v:
British journal of pharmacology. 124(2)
1. The aim of this study was to determine the response of porcine small pulmonary arteries to intralumenal flow and to identify the cellular mechanisms and potential mediators involved in the response. 2. Porcine small pulmonary arteries were isolate
Publikováno v:
British journal of pharmacology. 121(2)
1. The aim of the present study was to assess interactions between nitric oxide (NO) and prostacyclin (PGI2) during endothelium-dependent relaxations evoked by bradykinin, calcium ionophore (A23187) and acetylcholine in canine isolated pulmonary arte
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 257(1)
A pertussis toxin-sensitive guanine nucleotide regulatory protein (G-protein) is involved in the signal transduction of certain endothelium-dependent responses in mammalian arteries. To determine whether a similar mechanism mediates endothelium-depen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(1)
Activation of protein kinase C by phorbol esters inhibits the endothelium-dependent relaxations evoked by certain stimuli. The release of endothelium-derived relaxing factor can be evoked by a number of distinct subcellular processes, including activ
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 254(3)
The xanthine derivative 1-methyl 3-isobutyl 8-(2-ethyl[1-(4-diphenylmethyl piperazinyl)])3, 7-dihydro (1H) purine 2, 6-dione (S 9795) is a potent inhibitor of bronchoconstriction in vivo. The aim of the present study was to analyze the effects of S 9
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 252(3)
The present experiments were undertaken to investigate the electrophysiological responses of the canine saphenous vein evoked by perivascular nerve stimulation, norepinephrine or selective alpha adrenergic agonists before and after chronic sympatheti