Zobrazeno 1 - 10
of 35
pro vyhledávání: '"N. A. Elshourbagy"'
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 10, Pp 1011-1034 (1990)
During the past several years, the use of computer programs in the analysis of protein and DNA sequences has become commonplace. In all but the simplest procedures, the ability to critically review the results obtained with computer methods requires
Externí odkaz:
https://doaj.org/article/ba26b1f3157649b3acb7d85de81004f2
Autor:
Steve Lauer, Young‐Ki Paik, David Chang, Ellen Taxman, John M. Taylor, David Walker, Catherine A. Reardon, N A Elshourbagy
Publikováno v:
Ciba Foundation Symposium 130-Molecular Approaches to Human Polygenic Disease
The structures of the major human apolipoprotein genes have been determined. The genes for apoE, apoC-I, apoC-II, apoC-III, apoA-I, apoA-II and apoA-IV have similar structures, consisting of four exons and three introns, which suggests that they evol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b57d0a2490b922e57e7677619296e7
https://doi.org/10.1002/9780470513507.ch6
https://doi.org/10.1002/9780470513507.ch6
Autor:
M D, Wood, K L, Murkitt, S Q, Rice, T, Testa, P K, Punia, M, Stammers, O, Jenkins, N A, Elshourbagy, U, Shabon, S J, Taylor, T L, Gager, J, Minton, W D, Hirst, G W, Price, M, Pangalos
Publikováno v:
British journal of pharmacology. 131(6)
1. The aim of this study was to characterize the pharmacological profile of the GABA(B1)/GABA(B2) heterodimeric receptor expressed in Chinese hamster ovary (CHO) cells. We have compared receptor binding affinity and functional activity for a series o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e29a83bf37e1a5cacec0b8352617f8ae
https://pubmed.ncbi.nlm.nih.gov/11082110
https://pubmed.ncbi.nlm.nih.gov/11082110
Autor:
N A, Elshourbagy, X, Li, J, Terrett, S, Vanhorn, M S, Gross, J E, Adamou, K M, Anderson, C L, Webb, P G, Lysko
Publikováno v:
European journal of biochemistry. 267(3)
Murine MARCO has been identified recently in subsets of macrophages located in the peritoneum, marginal zone of the spleen, and the medullary cord of lymph nodes, where it has been proposed that it serves as a bacteria-binding receptor. A scavenger r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6183d69784271fe17cdb52da0f7a6160
https://pubmed.ncbi.nlm.nih.gov/10651831
https://pubmed.ncbi.nlm.nih.gov/10651831
Autor:
D, Smart, J C, Jerman, S J, Brough, S L, Rushton, P R, Murdock, F, Jewitt, N A, Elshourbagy, C E, Ellis, D N, Middlemiss, F, Brown
Publikováno v:
British journal of pharmacology. 128(1)
The cellular mechanisms underlying the physiological effects of the orexins are poorly understood. Therefore, the pharmacology of the recombinant human orexin receptors was studied using FLIPR. Intracellular calcium ([Ca2+]i) was monitored in Chinese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fd31e4f05a2302f663c56ddd6fbd113
https://pubmed.ncbi.nlm.nih.gov/10498827
https://pubmed.ncbi.nlm.nih.gov/10498827
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(3)
Class A scavenger receptor (SR-A) antagonists may prevent the initiation of atherosclerosis, because a recent report found that SR-A/apolipoprotein E (apoE) double-knockout mice had 60% smaller lesions than apoE single-knockout littermates. We transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d1f6628be892708e6cdc9aa06c16749
https://pubmed.ncbi.nlm.nih.gov/10336517
https://pubmed.ncbi.nlm.nih.gov/10336517
Autor:
H M, Sarau, D E, Griswold, W, Potts, J J, Foley, D B, Schmidt, E F, Webb, L D, Martin, M E, Brawner, N A, Elshourbagy, A D, Medhurst, G A, Giardina, D W, Hay
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(3)
The in vitro and in vivo pharmacological profile of SB 223412 [(S)-(-)-N-(alpha-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carbo xamide], a novel human NK-3 (hNK-3) receptor antagonist, is described. SB 223412 demonstrated enantioselective affinity f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9951a6d4717be264b3c6bd0fae47f6ba
https://pubmed.ncbi.nlm.nih.gov/9190866
https://pubmed.ncbi.nlm.nih.gov/9190866
1,3-Diarylindan-2-carboxylic acids, potent and selective non-peptide endothelin receptor antagonists
Autor:
Chandrika Kumar, J. A. Lee, J D Leber, N A Elshourbagy, Russell D. Cousins, K F Erhard, A Gao, John D. Elliott, Ponnal Nambi, M A Lago
Publikováno v:
Journal of medicinal chemistry. 37(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544e779a1e72c2abe2bbf3c73aa82ea6
https://pubmed.ncbi.nlm.nih.gov/8201588
https://pubmed.ncbi.nlm.nih.gov/8201588
Autor:
N A, Elshourbagy, D R, Korman, H L, Wu, D R, Sylvester, J A, Lee, P, Nuthalaganti, D J, Bergsma, C S, Kumar, P, Nambi
Publikováno v:
The Journal of biological chemistry. 268(6)
Endothelin receptors (ETRs) are distributed throughout a variety of tissues. Two human cDNAs were identified which encode distinct ETR proteins. One cDNA encoded a 427-amino acid protein that shared 91% identity to rat ETAR. The second cDNA encoded a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::907f864f19d854bb2a5522c7866c0251
https://pubmed.ncbi.nlm.nih.gov/8440682
https://pubmed.ncbi.nlm.nih.gov/8440682
Autor:
N A, Elshourbagy, J A, Lee, D R, Korman, P, Nuthalaganti, D R, Sylvester, A G, Dilella, J A, Sutiphong, C S, Kumar
Publikováno v:
Molecular pharmacology. 41(3)
Endothelin receptors (ETRs) display subtype heterogeneity and are widely distributed throughout the tissues of the periphery and central nervous system. In order to gain further insight into the potential molecular differences of ETRs, we initiated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29ddc0ce453905f96542b3b9c1e68a87
https://pubmed.ncbi.nlm.nih.gov/1312214
https://pubmed.ncbi.nlm.nih.gov/1312214