Zobrazeno 1 - 10
of 898
pro vyhledávání: '"N., Melo"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Transcription factors (TFs) bind to DNA in a highly sequence-specific manner. This specificity manifests itself in vivo as differences in TF occupancy between the two alleles at heterozygous loci. Genome-scale assays such as ChIP-
Externí odkaz:
https://doaj.org/article/203b6acd35344567af1a6e1d3e57ec39
Autor:
Shashank Dadsena, Rodrigo Cuevas Arenas, Gonçalo Vieira, Susanne Brodesser, Manuel N. Melo, Ana J. García-Sáez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract BAX and BAK are proapoptotic members of the BCL2 family that directly mediate mitochondrial outer membrane permeabilition (MOMP), a central step in apoptosis execution. However, the molecular architecture of the mitochondrial apoptotic pore
Externí odkaz:
https://doaj.org/article/2bee97a155664393b38bf835ce663f24
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S234-S235 (2024)
Introdução/Objetivos: O Linfoma do Manto e a Leucemia Linfoide Crônica (LLC) são doenças hematológicas que afetam o sistema linfático, apresentando características desafiadoras tanto para médicos quanto para pacientes. Os sintomas do Linfoma
Externí odkaz:
https://doaj.org/article/efdcf9c904884d8797db62ade0fb72ad
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S492-S493 (2024)
Introdução: A Mielofibrose é um câncer que afeta a medula óssea, do grupo das doenças mieloproliferativas crônicas. Pode se manifestar de duas formas: primária, quando não existe uma causa conhecida, e secundária, quando decorre de outras c
Externí odkaz:
https://doaj.org/article/2584a38ab34a4363bf32d474af00115b
Autor:
Tobias Weihrauch, Rossana C. N. Melo, Natalie Gray, David Voehringer, Peter F. Weller, Ulrike Raap
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
Eosinophil granulocytes, a specialized subset of white blood cells, have traditionally been associated with allergic responses and parasitic infections. However, recent research has unveiled their versatile roles in immune regulation beyond these cla
Externí odkaz:
https://doaj.org/article/e5c1d49cbf854c44bf03eea28a725a93
Autor:
Cayo Vinnycius Pereira Lima, José Ywgne, Mabliny Thuany, Raphael H. O. Araujo, Ellen C. M. Silva, João C. N. Melo, Paulo Felipe R Bandeira, Leonardo G. O. Luz, Danilo R. Silva
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Objective The current study aimed to explore the association of individual characteristics, social and environmental factors - school and region - in the intention to be physically active in Brazilian adolescents. Methods This is a cross sec
Externí odkaz:
https://doaj.org/article/1731558428b74c9882f28e9d3870ea0b
Autor:
Catarina J. Gaspar, Tiago Gomes, Joana C. Martins, Manuel N. Melo, Colin Adrain, Tiago N. Cordeiro, Pedro M. Domingos
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108309- (2023)
Summary: Rhodopsin-1 (Rh1), the main photosensitive protein of Drosophila, is a seven-transmembrane domain protein, which is inserted co-translationally in the endoplasmic reticulum (ER) membrane. Biogenesis of Rh1 occurs in the ER, where various cha
Externí odkaz:
https://doaj.org/article/d33cb3e63f994da2941e4244b8c4b3b1
Autor:
C. Freitas, B. Lima, N. Melo, P. Mota, H. Novais-Bastos, H. Alves, O. Sokhatska, L. Delgado, A. Morais
Publikováno v:
Pulmonology, Vol 29, Iss , Pp S63-S69 (2023)
Introduction: Since Hypersensitivity Pneumonitis (HP) categorization in fibrotic and nonfibrotic/inflammatory types seems to be more consistent with the distinctive clinical course and outcomes, recent international guidelines recommended the use of
Externí odkaz:
https://doaj.org/article/82f1b74cc0654b1aa3223938fa51450e
Autor:
David Valdivieso González, Marcin Makowski, M. Pilar Lillo, Francisco J. Cao‐García, Manuel N. Melo, Víctor G. Almendro‐Vedia, Iván López‐Montero
Publikováno v:
Advanced Science, Vol 10, Iss 31, Pp n/a-n/a (2023)
Abstract ATP synthases are proteins that catalyse the formation of ATP through the rotatory movement of their membrane‐spanning subunit. In mitochondria, ATP synthases are found to arrange as dimers at the high‐curved edges of cristae. Here, a di
Externí odkaz:
https://doaj.org/article/8e868af655b8479a87a2e90f1dc9f20e
Autor:
Eleonora Marini, Carmen Olivença, Sara Ramalhete, Andrea Martinez Aguirre, Patrick Ingle, Manuel N Melo, Wilson Antunes, Nigel P Minton, Guillem Hernandez, Tiago N Cordeiro, Joseph A Sorg, Mónica Serrano, Adriano O Henriques
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011741 (2023)
A genomic signature for endosporulation includes a gene coding for a protease, YabG, which in the model organism Bacillus subtilis is involved in assembly of the spore coat. We show that in the human pathogen Clostridioidesm difficile, YabG is critic
Externí odkaz:
https://doaj.org/article/7c0c299799724715ab006823f9bfa0a6