Zobrazeno 1 - 10
of 13 334
pro vyhledávání: '"N-oxide"'
Autor:
Vichai Senthong, Songsak Kiatchoosakun, Chaiyasith Wongvipaporn, Jutarop Phetcharaburanin, Piyamitr Sritara, Arintaya Phrommintikul, CORE Investigators
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract The gut microbiota metabolite trimethylamine-N-oxide (TMAO)—derived from dietary phosphatidylcholine—is mechanistically linked to cardiovascular disease (CVD) and increased cardiovascular risk. This study examined the relationship betwee
Externí odkaz:
https://doaj.org/article/0bb4f973e8d04962810ba84cf711af35
Autor:
Olesia Vasetska, Inna Rashkivska
Publikováno v:
Біологічні студії, Vol 18, Iss 3, Pp 47-56 (2024)
Background. Global anthropogenic environmental pollution, intensification of production, daily physical, emotional and psychogenic stress on humans, as well as the working environment provoke a variety of diseases, fatigue, and cognitive impairment,
Externí odkaz:
https://doaj.org/article/bed261943fe14eafb84bfb9614dfd1f3
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)
Abstract Background Tissue fibrosis is a common pathway to failure in many organ systems and is the cellular and molecular driver of myriad chronic diseases that are incompletely understood and lack effective treatment. Recent studies suggest that gu
Externí odkaz:
https://doaj.org/article/19f2647031c24b9c9673e8e317340e79
Autor:
Chunfang Zhou, Rina Basnet, Chenxiang Zhen, Shinan Ma, Xingrong Guo, Zhongxia Wang, Yahong Yuan
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Trimethylamine-n-oxide (TMAO) is a metabolite of intestinal flora following the consumption of phosphatidylcholine-rich foods. Clinical cohort studies have shown that plasma TMAO may be a risk factor for cancer development, including hepatoc
Externí odkaz:
https://doaj.org/article/fd73694473c14d89b5a826afac4e6c24
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 3617-3628 (2024)
Lin Cheng, Xi You, Xiaowen Wang, Mingjie Yu, Changsheng Jia Department of Pharmacy, the First Affiliated Hospital of Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Lin Cheng; Mingjie Yu, Email cheng7zhu@163.com; ymjxn
Externí odkaz:
https://doaj.org/article/0810dc12dfcf4ac7a2c1a60c908547d6
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 8, Pp 732-743 (2024)
Abstract An increasing number of elderly individuals are experiencing postoperative cognitive dysfunction (POCD) problems after undergoing hip replacement surgery, with gut microbiota metabolites playing a role in its pathogenesis. Among these, the s
Externí odkaz:
https://doaj.org/article/2ffb4d65311d4c12b77de0979ac75ce5
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract Ensuring the quality control of active pharmaceutical ingredients is crucial for drug products being introduced into the market. Even for established drugs, it is necessary to maintain a cutting-edge impurity control system. To analyze caffe
Externí odkaz:
https://doaj.org/article/a4eb9adc4a4a42f09d5605ffacf909b9
Autor:
Christian Näther, Inke Jess
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 80, Iss 7, Pp 704-708 (2024)
The reaction of CoBr2, KNCSe and 2-methylpyridine N-oxide (C6H7NO) in ethanol leads to the formation of crystals of [Co(NCSe)2(C6H7NO)3] (1) and [Co(NCSe)2(C6H7NO)4] (2) from the same reaction mixture. The asymmetric unit of 1 is built up of one CoII
Externí odkaz:
https://doaj.org/article/9779d9fff084411188204f5dbb956002
Autor:
Saba Naghipour, Amanda J. Cox, Joshua J. Fisher, Manuel Plan, Terra Stark, Nic West, Jason N. Peart, John P. Headrick, Eugene F. Du Toit
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Elevations in the gut metabolite trimethylamine-N-oxide (TMAO) have been linked to cardiovascular and metabolic diseases. Whether elevated TMAO levels reflect early mechanistic involvement or a sequela of evolving disease awaits e
Externí odkaz:
https://doaj.org/article/923a727145144a42a62bb33516abf139
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Dapagliflozin (DAPA) demonstrates promise in the management of diabetic mellitus (DM) and cardiomyopathy. Trimethylamine N-oxide (TMAO) is synthesized by the gut microbiota through the metabolic conversion of choline and phosphatidylcholine.
Externí odkaz:
https://doaj.org/article/ca12b45fb0b64c169b46846205c7f716