Zobrazeno 1 - 10
of 8 965
pro vyhledávání: '"N-glycosylation"'
Autor:
Bi Ming, Tian Zhixin
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1172-1183 (2024)
N-linked glycosylation is a common posttranslational modification of proteins that results in macroheterogeneity of the modification site. However, unlike simpler modifications, N-glycosylation introduces an additional layer of complexity with tens o
Externí odkaz:
https://doaj.org/article/24d3684a9fb14758a8563891eddc4486
Autor:
Hirokazu Yagi, Seigo Tateo, Taiki Saito, Yusaku Ohta, Emiko Nishi, Saemi Obitsu, Tatsuya Suzuki, Supaphorn Seetaha, Charles Hellec, Akihiko Nakano, Takuro Tojima, Koichi Kato
Publikováno v:
Cell Structure and Function, Vol 49, Iss 2, Pp 47-55 (2024)
The Golgi apparatus, a crucial organelle involved in protein processing, including glycosylation, exhibits complex sub-structures, i.e., cis-, medial, and trans-cisternae. This study investigated the distribution of glycosyltransferases within the Go
Externí odkaz:
https://doaj.org/article/773bbe37ee2c4458984c2ab5ac35d2e1
Autor:
Tamas Pongracz, Maaike Biewenga, Anna Eva Charlotte Stoelinga, Marco René Bladergroen, Simone Nicolardi, Leendert Adrianus Trouw, Manfred Wuhrer, Noortje de Haan, Bart van Hoek
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Changes in plasma protein glycosylation are known to functionally affect proteins and to associate with liver diseases, including cirrhosis and hepatocellular carcinoma. Autoimmune hepatitis (AIH) is a liver disease characterized
Externí odkaz:
https://doaj.org/article/61e5e7969808451f972e37479229dac5
Autor:
Jordan S. Dialpuri, Haroldas Bagdonas, Lucy C. Schofield, Phuong Thao Pham, Lou Holland, Jon Agirre
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 931-939 (2024)
The remediation of the carbohydrate data of the Protein Data Bank (PDB) has brought numerous enhancements to the findability and interpretability of deposited glycan structures, yet crucial quality indicators are either missing or hard to find on the
Externí odkaz:
https://doaj.org/article/c76ce5f10712417281506b4c1f0948fc
Autor:
Maria C. Rodriguez Benavente, Zainab A. Hakeem, Alexander R. Davis, Nathan B. Murray, Parastoo Azadi, Emily M. Mace, Adam W. Barb
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Natural killer (NK) cells destroy tissue that have been opsonized with antibodies. Strategies to generate or identify cells with increased potency are expected to enhance NK cell-based immunotherapies. We previously generated NK cells with i
Externí odkaz:
https://doaj.org/article/af037a6d23824e0396d24c7b526b7a61
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Evolution shapes protein sequences for their functions. Here, we studied the moonlighting functions of the N-linked sequon NXS/T, where X is not P, in human nucleocytosolic proteins. By comparing membrane and secreted proteins in which sequo
Externí odkaz:
https://doaj.org/article/f5cb5f74e9bf44b1afdb4b553bbc825a
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Various species of campylobacters cause significant disease problems in both humans and animals. The continuing development of tools and methods for genetic and molecular manipulation of campylobacters enables the detailed study of bacterial
Externí odkaz:
https://doaj.org/article/c98e9f6c6adf4029a8c8c1cb43a9831b
Autor:
An-Dong Wang, Yu-Xi Shen, Shu-Yun Li, Hai-Li Zhang, Di Wang, Zhong-Wei Guo, Ya-Mei Huang, Min Cui, Jing Xia, Yong Huang
Publikováno v:
Poultry Science, Vol 103, Iss 9, Pp 103991- (2024)
ABSTRACT: The S2 subunit of infectious bronchitis virus (IBV) is a heavily glycosylated protein that can impact various characteristics of the virus. It is currently known that N-glycosylation modifications are predominantly located on the S2 subunit
Externí odkaz:
https://doaj.org/article/bdfe673e4ddf4131ad80e326af0ba092
Publikováno v:
Vaccine: X, Vol 19, Iss , Pp 100531- (2024)
Since 2022, three human cases of a novel H3N8 avian influenza virus infection have been reported in three provinces in China. Specific vaccines are important means of preparing for the potential influenza pandemic. Thus, H3N8 viruses [A/Henan/cnic410
Externí odkaz:
https://doaj.org/article/b16ff2d87fbb410493ebb5d2f300be2f
Autor:
Simona Saporiti, Davide Bianchi, Omar Ben Mariem, Mara Rossi, Uliano Guerrini, Ivano Eberini, Fabio Centola
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionN-glycosylation is a post-translational modification that is highly important for the development of monoclonal antibodies (mAbs), as it regulates their biological activity, particularly in terms of immune effector functions. While typica
Externí odkaz:
https://doaj.org/article/f8f10b3d86614d7f855588dde31c64e0