Zobrazeno 1 - 10
of 771
pro vyhledávání: '"N-ACETYLTRANSFERASE 2"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionArylamine N-acetyltransferase 2 (NAT2) expresses a well-defined genetic polymorphism in humans that modifies drug and xenobiotic metabolism. Recent studies and genome wide association studies have reported that genetic variants of NAT2 ar
Externí odkaz:
https://doaj.org/article/4175c5e31b5e4fdc84cf8a99ae730b1c
Publikováno v:
International Journal of Mycobacteriology, Vol 13, Iss 2, Pp 206-212 (2024)
Background: Pharmacogenetic research has led to significant progress in understanding how genetic factors influence drug response in tuberculosis (TB) treatment. One ongoing challenge is the variable occurrence of adverse drug reactions in some TB pa
Externí odkaz:
https://doaj.org/article/f2b859134d1445a4b3e3e6a1b6b714b3
Autor:
Jarrar Y, Abudahab S, Abdul-Wahab G, Zaiter D, Madani A, Abaalkhail SJ, Abulebdah D, Alhawari H, Musleh R, Lee SJ
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol Volume 16, Pp 847-857 (2023)
Yazun Jarrar,1 Sara Abudahab,2 Ghasaq Abdul-Wahab,3 Dana Zaiter,4 Abdalla Madani,4 Sara J Abaalkhail,4 Dina Abulebdah,4 Hussam Alhawari,5 Rami Musleh,6 Su-Jun Lee7 1Department of Basic Medical Sciences, Faculty of Medicine, Al-Balqa Applied Universit
Externí odkaz:
https://doaj.org/article/321689e4a7b44a97b4e46e0269d9934c
Autor:
Márcia Quinhones P. Lopes, Raquel Lima F. Teixeira, Pedro Hernan Cabello, José Augusto C. Nery, Anna Maria Sales, Edilbert Pellegrini Nahn J. R., Marilda Vieira Moreira, Ewalda Von Rosen Stahlke, Lia Gonçalves Possuelo, Maria Lucia R. Rossetti, Marcelo F. Rabahi, Luciana F. M. Silva, Patrícia Almeida Leme, William John Woods, Mauricio Lisboa Nobre, Maria Leide Wan-Del-Rey de Oliveira, Kazuê Narahashi, Milde Cavalcanti, Philip Noel Suffys, Sotiria Boukouvala, Maria Eugênia N. Gallo, Adalberto Rezende Santos
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Several polymorphisms altering the NAT2 activity have already been identified. The geographical distribution of NAT2 variants has been extensively studied and has been demonstrated to vary significantly among different ethnic population
Externí odkaz:
https://doaj.org/article/eb92ce59510f48f8a05329b36d2ff020
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Arylamine N-acetyltransferase 2 (NAT2) is a phase II metabolic enzyme, best known for metabolism of aromatic amines and hydrazines. Genetic variants occurring in the NAT2 coding region have been well-defined and are known to affect the enzyme activit
Externí odkaz:
https://doaj.org/article/3eae20c69c6d4ce1aad7b6ce9110551a
Autor:
N. M. Krasnova, S. G. Efremenko, N. E. Evdokimova, O. I. Filippova, Y. V. Chertovskikh, E. A. Alekseeva, O. V. Tatarinova, A. I. Gotovtseva, E. S. Prokopev, A. F. Kravchenko, A. I. Vengerovskiy, D. A. Sychev
Publikováno v:
Антибиотики и Химиотерапия, Vol 66, Iss 9-10, Pp 30-38 (2022)
Background. Individual sensitivity to isoniazid in tuberculosis patients is determined by the presence of N-acetyltransferase 2 (NAT2) enzyme gene allelic variants in genome. Evaluation of quantitative and qualitative alterations in peripheral blood
Externí odkaz:
https://doaj.org/article/1807d5839d4b421db7bf77f21de4e463
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Oftalʹmologiâ, Vol 18, Iss 3, Pp 546-551 (2021)
Aim — to study of gene polymorphisms affecting the effectiveness of timolol treatment of primary open-angle glaucoma.Patients and Methods. The study included 39 Russian patients (29 women and 10 men) aged 53 to 89 years old with a diagnosis of prim
Externí odkaz:
https://doaj.org/article/bc6b3f1a053547fbae6399b33290cd7c
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1471 (2023)
Amifampridine is a drug used for the treatment of Lambert–Eaton myasthenic syndrome (LEMS) and was approved by the Food and Drug Administration (FDA) of the United States (US) in 2018. It is mainly metabolized by N-acetyltransferase 2 (NAT2); howev
Externí odkaz:
https://doaj.org/article/9a9cf9fcb0bf47d08ffb9b46f466a9cb
Autor:
A. A. Kachanova, Yu. A. Pimenova, G. N. Shuev, K. A. Akmalova, Zh. A. Sozaeva, N. M. Krasnova, E. A. Grishina, D. A. Sychev
Publikováno v:
Безопасность и риск фармакотерапии, Vol 9, Iss 1, Pp 25-33 (2021)
Tuberculosis remains one of the most dangerous and widespread infectious diseases. More than 20 medicinal products are currently available for the treatment of tuberculosis. One of the most serious adverse drug reactions (ADRs) associated with anti-t
Externí odkaz:
https://doaj.org/article/054b051ced3145b0846baa036ed77e6f