Výsledky vyhledávání - "N Yu, Safronova"

Somatic mutation profiling and functioning of intracellular signaling pathways at various stages of bladder cancer and their significance for targeted therapy

Autor: N. Yu. Safronova, G. D. Efremov, Andrey Kaprin, Dmitry S. Mikhaylenko, B. Ya. Alekseev, S. A. Sergienko

Publikováno v: Experimental and Сlinical Urology. 12:42-51

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aac76a9e58863a123a7916c2bc264687
https://doi.org/10.29188/2222-8543-2020-12-1-42-51

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The role of molecular genetic alterations in sensitivity of the adjuvant intravesical therapy for non-muscle invasive bladder cancer

Autor: D. S. Mikhaylenko, S. A. Sergienko, I. N. Zaborsky, K. N. Saflullin, S. A. Serebryany, N. Yu. Safronova, M. V. Nemtsova, A. D. Kaprin, B. Ya. Alekseev

Publikováno v: Onkourologiâ, Vol 14, Iss 4, Pp 124-138 (2019)

Bladder cancer (BC) is represented by non-muscle-invasive forms at the stage Ta, T1, CIS (NMBC) in 75 % of cases. The gold standard of treatment of NMBC patients is transurethral resection, but its implementation does not always allow the patient to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f575ebae38d777157db2a6cc0b99831
https://doi.org/10.17650/1726-9776-2018-14-4-124-138

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Comparative analysis of the PCA3 gene expression in sediments and exosomes isolated from urine

Autor: D. S. Mikhaylenko, A. A. Novikov, M. V. Grigor’eva, G. D. Efremov, A. V. Sivkov, N. Yu. Safronova, K. S. Sorokin, M. Yu. Zemskova, M. V. Nemtsova, B. Ya. Alekseev, A. D. Kaprin

Publikováno v: Onkourologiâ, Vol 13, Iss 3, Pp 54-60 (2017)

Introduction . Prostate cancer (PCa) is one of the common oncological diseases in men. Expression of the PCA3 gene in urine is currently used as a molecular genetic marker of PCa. Objective: to comparative analysis of the PCA3 expression in urine sed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330fcfbc19925bb05835835e76a79188
https://oncourology.abvpress.ru/oncur/article/view/685

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[PCA3 AND TMPRSS2:ERG GENES EXPRESSION IN BIOPSIES OF BENIGN PROSTATE HYPERPLASIA, INTRAEPITHELIAL NEOPLASIA, AND PROSTATE CANCER]

Autor: D S, Mikhaylenko, D V, Perepechin, M V, Grigoryeva, T A, Zhinzhilo, N Yu, Safronova, G D, Efremov, A V, Sivkov

Publikováno v: Urologiia (Moscow, Russia : 1999). (5)

Morphological analysis of the biopsies for prostate cancer (PCa) often is a difficult task due to heterogeneity and multifocality of tumors. At the same time, a lot of data exist about the potential molecular genetic markers of PCa. The aim of our st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8d0c2ac522fa10405afa0e388dbcf03
https://pubmed.ncbi.nlm.nih.gov/26859937

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Detection of Rare Mutations by Routine Analysis of KRAS, NRAS, and BRAF Oncogenes

Autor: G. D. Efremov, D. S. Mikhailenko, Vladimir V Strelnikov, B. Ya. Alekseev, N. Yu. Safronova

Publikováno v: Bulletin of experimental biology and medicine. 162(3)

Molecular genetic analysis of KRAS, NRAS, and BRAF genes was carried out in order to develop an optimal algorithm for detection of minor mutations. We analyzed 35 melanoma and 33 colorectal cancer specimens. Frequent G12D/V/A/C/S mutations were detec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68ed8316f55ff47a9dd72771db71013
https://pubmed.ncbi.nlm.nih.gov/28091917

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