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Akademický článek

A phase I study of docetaxel plus synthetic lycopene in metastatic prostate cancer patients

Autor: Michael B. Lilly, Chunli Wu, Yu Ke, Wen‐Pin Chen, Adam C. Soloff, Kent Armeson, Noriko N. Yokoyama, Xiaotian Li, Liankun Song, Ying Yuan, Christine E. McLaren, Xiaolin Zi

Publikováno v: Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)

Abstract Purpose Our preclinical studies showed that lycopene enhanced the anti‐prostate cancer efficacy of docetaxel in animal models. A phase I trial (NCT0149519) was conducted to identify an optimum dose of synthetic lycopene in combination with

Externí odkaz: https://doaj.org/article/5c65eef1c6c54d5eaf06f95c1a59df0d

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The Potent Anti-Tumor Effects of Rhodiola Drinking Are Associated with the Inhibition of the mTOR Pathway and Modification of Tumor Metabolism in the UPII-Mutant Ha-Ras Model

Autor: Zi, Zhongbo Liu, Noriko N Yokoyama, Liankun Song, Jun Xie, Zhina Sadeghi, Yi Xi Wu, Sarah Yee, Xue-Ru Wu, Beverly Wang, Edward Uchio, Xiaolin

Publikováno v: Cancers; Volume 15; Issue 12; Pages: 3086

Background: SHR-5 has been used as an “adaptogen” for enhancing physical and mental performance and for fighting stress in the healthy population. The purpose of this study is to determine the chemopreventive efficacy of SHR-5 for superficial bla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::43268ce180c0662497ed7cd26bb0cf2f

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Supplementary Figure 1: The effect of metformin on bladder tumorigenesis from High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ∼240-Fold Higher Drug Concentration in Urine than Serum

Autor: Xiaolin Zi, Michael Pollak, Michael McClelland, Ramy Youssef, Edward Uchio, Xue-Ru Wu, Daina Avizonis, Xuesen Li, Christopher A. Blair, Noriko N. Yokoyama, Zhongbo Liu

Comparison of average body weight and water consumption over time between control and metformin treated male UPII-Ha-ras transgenic mice.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593b8d0b43b82edb21178678118d93bd
https://doi.org/10.1158/1535-7163.22504041

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Data from High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ∼240-Fold Higher Drug Concentration in Urine than Serum

Autor: Xiaolin Zi, Michael Pollak, Michael McClelland, Ramy Youssef, Edward Uchio, Xue-Ru Wu, Daina Avizonis, Xuesen Li, Christopher A. Blair, Noriko N. Yokoyama, Zhongbo Liu

While pharmacoepidemiologic and laboratory studies have supported the hypothesis that the antidiabetic drug metformin may be useful in treating or preventing cancer, there is limited evidence to suggest which specific cancer sites may be particularly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539de505e8673bd87ab1375e7fa04aea
https://doi.org/10.1158/1535-7163.c.6537603.v1

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Specifications of the ACMG/AMP Variant Classification Guidelines for Germline DICER1 Variant Curation

Publikováno v: Human Mutation.

Germline pathogenic variants in DICER1 predispose individuals to develop a variety of benign and malignant tumors. Accurate variant curation and classification are essential for reliable diagnosis of DICER1-related tumor predisposition and the identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06fb74ca28123e143c4945b524fb329

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Akademický článek

Edge-spin-derived magnetism in few-layer MoS2 nanomeshes

Autor: G. Kondo, N. Yokoyama, S. Yamada, Y. Hashimoto, C. Ohata, S. Katsumoto, J. Haruyama

Publikováno v: AIP Advances, Vol 7, Iss 12, Pp 125019-125019-7 (2017)

Magnetism arising from edge spins is highly interesting, particularly in 2D atomically thin materials in which the influence of edges becomes more significant. Among such materials, molybdenum disulfide (MoS2; one of the transition metal dichalcogeni

Externí odkaz: https://doaj.org/article/9b50d056f9304a5c8f7b3f268513ffd0

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